A cross-sectional and 6-year follow-up study of associations between leisure time physical activity and vertebral fracture in adults
INTRODUCTION: Vertebral fractures are common osteoporotic fractures, affecting 2–46% of the population, causing morbidity and increased risk of mortality. Physical activity has beneficial effects for bone health, including increased bone mineral density and reduced hip fractures. However, evidence c...
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ftpubmed:oai:pubmedcentral.nih.gov:6747745 2023-05-15T18:34:55+02:00 A cross-sectional and 6-year follow-up study of associations between leisure time physical activity and vertebral fracture in adults Mikkilä, Saija Calogiuri, Giovanna Emaus, Nina Morseth, Bente 2019-09-17 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6747745/ http://www.ncbi.nlm.nih.gov/pubmed/31526375 https://doi.org/10.1186/s12891-019-2821-8 en eng BioMed Central http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6747745/ http://www.ncbi.nlm.nih.gov/pubmed/31526375 http://dx.doi.org/10.1186/s12891-019-2821-8 © The Author(s). 2019 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. CC0 PDM CC-BY Research Article Text 2019 ftpubmed https://doi.org/10.1186/s12891-019-2821-8 2019-09-22T00:31:08Z INTRODUCTION: Vertebral fractures are common osteoporotic fractures, affecting 2–46% of the population, causing morbidity and increased risk of mortality. Physical activity has beneficial effects for bone health, including increased bone mineral density and reduced hip fractures. However, evidence concerning prevention of vertebral fractures is scarce. Therefore, the aim of this study was to investigate the association between leisure time physical activity and vertebral fracture risk. METHODS: The data were retrieved from the 2001 and 2007–2008 surveys of the Tromsø Study, a longitudinal population study in Norway. A total of 1904 participants (1030 women and 874 men, age 38–87 yr and 40–87 yr respectively) were included in the cross-sectional analysis (2007–2008). Prospective follow-up data (2001 to 2007) on physical activity were available for 1131 participants (636 women and 495 men, age 32–69 yr and 33–69 yr respectively). Physical activity was assessed by a questionnaire and vertebral fracture by lateral vertebral fracture assessment from dual-energy x-ray absorptiometry scans. Logistic regression was used to examine associations between physical activity and vertebral fracture. RESULTS: After controlling for confounders (age, height, weight, smoking, osteoporosis, osteoporosis medication, left hip total bone mineral density, and use of hormones in women only), no cross-sectional associations between physical activity levels and vertebral fracture were observed, OR 1.13 (95% CI: 0.59–2.13), for moderately active women and 1.44 (0.61–3.42) for highly active women, compared with sedentary women. In men, the respective ORs were 1.74 (95% CI: 0.91–3.35) and 1.64 (0.78–3.41). In the prospective analyses, OR for vertebral fracture in women with reduced physical activity was 0.81 (95% CI: 0.18–3.62), 1.24 (95% CI: 0.29–5.26) for increased physical activity and 1.54 (95% CI: 0.43–5.50) for active unchanged physical activity pattern, compared with sedentary unchanged physical activity. In men, the respective ORs ... Text Tromsø PubMed Central (PMC) Norway Tromsø BMC Musculoskeletal Disorders 20 1 |
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Research Article Mikkilä, Saija Calogiuri, Giovanna Emaus, Nina Morseth, Bente A cross-sectional and 6-year follow-up study of associations between leisure time physical activity and vertebral fracture in adults |
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Research Article |
description |
INTRODUCTION: Vertebral fractures are common osteoporotic fractures, affecting 2–46% of the population, causing morbidity and increased risk of mortality. Physical activity has beneficial effects for bone health, including increased bone mineral density and reduced hip fractures. However, evidence concerning prevention of vertebral fractures is scarce. Therefore, the aim of this study was to investigate the association between leisure time physical activity and vertebral fracture risk. METHODS: The data were retrieved from the 2001 and 2007–2008 surveys of the Tromsø Study, a longitudinal population study in Norway. A total of 1904 participants (1030 women and 874 men, age 38–87 yr and 40–87 yr respectively) were included in the cross-sectional analysis (2007–2008). Prospective follow-up data (2001 to 2007) on physical activity were available for 1131 participants (636 women and 495 men, age 32–69 yr and 33–69 yr respectively). Physical activity was assessed by a questionnaire and vertebral fracture by lateral vertebral fracture assessment from dual-energy x-ray absorptiometry scans. Logistic regression was used to examine associations between physical activity and vertebral fracture. RESULTS: After controlling for confounders (age, height, weight, smoking, osteoporosis, osteoporosis medication, left hip total bone mineral density, and use of hormones in women only), no cross-sectional associations between physical activity levels and vertebral fracture were observed, OR 1.13 (95% CI: 0.59–2.13), for moderately active women and 1.44 (0.61–3.42) for highly active women, compared with sedentary women. In men, the respective ORs were 1.74 (95% CI: 0.91–3.35) and 1.64 (0.78–3.41). In the prospective analyses, OR for vertebral fracture in women with reduced physical activity was 0.81 (95% CI: 0.18–3.62), 1.24 (95% CI: 0.29–5.26) for increased physical activity and 1.54 (95% CI: 0.43–5.50) for active unchanged physical activity pattern, compared with sedentary unchanged physical activity. In men, the respective ORs ... |
format |
Text |
author |
Mikkilä, Saija Calogiuri, Giovanna Emaus, Nina Morseth, Bente |
author_facet |
Mikkilä, Saija Calogiuri, Giovanna Emaus, Nina Morseth, Bente |
author_sort |
Mikkilä, Saija |
title |
A cross-sectional and 6-year follow-up study of associations between leisure time physical activity and vertebral fracture in adults |
title_short |
A cross-sectional and 6-year follow-up study of associations between leisure time physical activity and vertebral fracture in adults |
title_full |
A cross-sectional and 6-year follow-up study of associations between leisure time physical activity and vertebral fracture in adults |
title_fullStr |
A cross-sectional and 6-year follow-up study of associations between leisure time physical activity and vertebral fracture in adults |
title_full_unstemmed |
A cross-sectional and 6-year follow-up study of associations between leisure time physical activity and vertebral fracture in adults |
title_sort |
cross-sectional and 6-year follow-up study of associations between leisure time physical activity and vertebral fracture in adults |
publisher |
BioMed Central |
publishDate |
2019 |
url |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6747745/ http://www.ncbi.nlm.nih.gov/pubmed/31526375 https://doi.org/10.1186/s12891-019-2821-8 |
geographic |
Norway Tromsø |
geographic_facet |
Norway Tromsø |
genre |
Tromsø |
genre_facet |
Tromsø |
op_relation |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6747745/ http://www.ncbi.nlm.nih.gov/pubmed/31526375 http://dx.doi.org/10.1186/s12891-019-2821-8 |
op_rights |
© The Author(s). 2019 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
op_rightsnorm |
CC0 PDM CC-BY |
op_doi |
https://doi.org/10.1186/s12891-019-2821-8 |
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BMC Musculoskeletal Disorders |
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20 |
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1 |
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