Changes of median nerve conduction, cross-sectional area and mobility by radioulnar wrist compression intervention in patients with carpal tunnel syndrome
BACKGROUND: Owing to the compressive nature of the neuropathy, patients with carpal tunnel syndrome (CTS) have prolonged distal motor latency (DML), sensory nerve latency (SNL), median nerve swelling and restricted median nerve mobility. The purpose of this study was to noninvasively augment carpal...
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ftpubmed:oai:pubmedcentral.nih.gov:6718919 2023-05-15T16:01:25+02:00 Changes of median nerve conduction, cross-sectional area and mobility by radioulnar wrist compression intervention in patients with carpal tunnel syndrome Yao, Yifei Grandy, Emily Jenkins, Lenicia Hou, Juliet Evans, Peter J. Seitz, William H. Li, Zong-Ming 2019-02-14 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6718919/ http://www.ncbi.nlm.nih.gov/pubmed/31508303 https://doi.org/10.1016/j.jot.2019.01.002 en eng Chinese Speaking Orthopaedic Society http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6718919/ http://www.ncbi.nlm.nih.gov/pubmed/31508303 http://dx.doi.org/10.1016/j.jot.2019.01.002 © 2019 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). CC-BY-NC-ND Original Article Text 2019 ftpubmed https://doi.org/10.1016/j.jot.2019.01.002 2019-09-15T00:15:45Z BACKGROUND: Owing to the compressive nature of the neuropathy, patients with carpal tunnel syndrome (CTS) have prolonged distal motor latency (DML), sensory nerve latency (SNL), median nerve swelling and restricted median nerve mobility. The purpose of this study was to noninvasively augment carpal tunnel space using radioulnar wrist compression (RWC) and evaluate its effects on median nerve pathological properties in patients with CTS. It was hypothesized that the RWC intervention would reduce the median nerve DML, SNL and cross-sectional area (CSA) and enhance longitudinal median nerve mobility in patients. with CTS. METHODS: Eleven patients diagnosed with CTS participated in this study. A portable RWC intervention splint was developed to apply 10 N of compressive force across the wrist. Three daily sessions of RWC were performed over 4 weeks of intervention (15 min per session, 45 min per day, 7 days per week). Each 15-min session consisted of three 5-min blocks of RWC, with a 1-min rest in between consecutive blocks. Patients were evaluated at Week 0 (baseline), Week 2 (mid-intervention) and Week 4 (end of intervention). DML and SNL of the median nerve were evaluated using established nerve conduction study techniques. Median nerve CSA at the distal wrist crease was obtained by ultrasound imaging. Median nerve motion associated with finger flexion/extension was captured by dynamic ultrasound imaging and quantified using a speckle cross-correlation algorithm. Finger flexion/extension was recorded using an electrogoniometer. The slope of the regressed linear equation of median nerve displacement as a function of finger flexion angle was used to quantify nerve mobility. RESULTS: Patients with CTS showed significantly decreased DML (p = 0.048) and median nerve CSA (p < 0.001) and increased nerve mobility (p < 0.001) at mid-intervention compared to baseline. However, DML, CSA and mobility of the median nerve did not differ significantly between Weeks 2 and 4 (p = 0.574, 1.00 and 0.139, respectively). Median ... Text DML PubMed Central (PMC) Journal of Orthopaedic Translation 18 13 19 |
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Original Article Yao, Yifei Grandy, Emily Jenkins, Lenicia Hou, Juliet Evans, Peter J. Seitz, William H. Li, Zong-Ming Changes of median nerve conduction, cross-sectional area and mobility by radioulnar wrist compression intervention in patients with carpal tunnel syndrome |
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Original Article |
description |
BACKGROUND: Owing to the compressive nature of the neuropathy, patients with carpal tunnel syndrome (CTS) have prolonged distal motor latency (DML), sensory nerve latency (SNL), median nerve swelling and restricted median nerve mobility. The purpose of this study was to noninvasively augment carpal tunnel space using radioulnar wrist compression (RWC) and evaluate its effects on median nerve pathological properties in patients with CTS. It was hypothesized that the RWC intervention would reduce the median nerve DML, SNL and cross-sectional area (CSA) and enhance longitudinal median nerve mobility in patients. with CTS. METHODS: Eleven patients diagnosed with CTS participated in this study. A portable RWC intervention splint was developed to apply 10 N of compressive force across the wrist. Three daily sessions of RWC were performed over 4 weeks of intervention (15 min per session, 45 min per day, 7 days per week). Each 15-min session consisted of three 5-min blocks of RWC, with a 1-min rest in between consecutive blocks. Patients were evaluated at Week 0 (baseline), Week 2 (mid-intervention) and Week 4 (end of intervention). DML and SNL of the median nerve were evaluated using established nerve conduction study techniques. Median nerve CSA at the distal wrist crease was obtained by ultrasound imaging. Median nerve motion associated with finger flexion/extension was captured by dynamic ultrasound imaging and quantified using a speckle cross-correlation algorithm. Finger flexion/extension was recorded using an electrogoniometer. The slope of the regressed linear equation of median nerve displacement as a function of finger flexion angle was used to quantify nerve mobility. RESULTS: Patients with CTS showed significantly decreased DML (p = 0.048) and median nerve CSA (p < 0.001) and increased nerve mobility (p < 0.001) at mid-intervention compared to baseline. However, DML, CSA and mobility of the median nerve did not differ significantly between Weeks 2 and 4 (p = 0.574, 1.00 and 0.139, respectively). Median ... |
format |
Text |
author |
Yao, Yifei Grandy, Emily Jenkins, Lenicia Hou, Juliet Evans, Peter J. Seitz, William H. Li, Zong-Ming |
author_facet |
Yao, Yifei Grandy, Emily Jenkins, Lenicia Hou, Juliet Evans, Peter J. Seitz, William H. Li, Zong-Ming |
author_sort |
Yao, Yifei |
title |
Changes of median nerve conduction, cross-sectional area and mobility by radioulnar wrist compression intervention in patients with carpal tunnel syndrome |
title_short |
Changes of median nerve conduction, cross-sectional area and mobility by radioulnar wrist compression intervention in patients with carpal tunnel syndrome |
title_full |
Changes of median nerve conduction, cross-sectional area and mobility by radioulnar wrist compression intervention in patients with carpal tunnel syndrome |
title_fullStr |
Changes of median nerve conduction, cross-sectional area and mobility by radioulnar wrist compression intervention in patients with carpal tunnel syndrome |
title_full_unstemmed |
Changes of median nerve conduction, cross-sectional area and mobility by radioulnar wrist compression intervention in patients with carpal tunnel syndrome |
title_sort |
changes of median nerve conduction, cross-sectional area and mobility by radioulnar wrist compression intervention in patients with carpal tunnel syndrome |
publisher |
Chinese Speaking Orthopaedic Society |
publishDate |
2019 |
url |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6718919/ http://www.ncbi.nlm.nih.gov/pubmed/31508303 https://doi.org/10.1016/j.jot.2019.01.002 |
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op_relation |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6718919/ http://www.ncbi.nlm.nih.gov/pubmed/31508303 http://dx.doi.org/10.1016/j.jot.2019.01.002 |
op_rights |
© 2019 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
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CC-BY-NC-ND |
op_doi |
https://doi.org/10.1016/j.jot.2019.01.002 |
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Journal of Orthopaedic Translation |
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18 |
container_start_page |
13 |
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19 |
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1766397288466350080 |