Prevalence of Essential Tremor in the Faroe Islands: A Population-Based Study
BACKGROUND: No studies of the prevalence of one of the most common movement disorders, essential tremor (ET), have been undertaken in the Faroe Islands. Given the potential for founder effects in the Islands, and the highly genetic nature of ET, the Faroe Islands provide a particularly interesting s...
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ftpubmed:oai:pubmedcentral.nih.gov:6626989 2023-05-15T16:10:26+02:00 Prevalence of Essential Tremor in the Faroe Islands: A Population-Based Study Eliasen, Eina H. Ferrer, Monica Gaini, Shahin Louis, Elan D. Petersen, Maria Skaalum 2019-03-19 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6626989/ http://www.ncbi.nlm.nih.gov/pubmed/30889566 https://doi.org/10.1159/000499070 en eng http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6626989/ http://www.ncbi.nlm.nih.gov/pubmed/30889566 http://dx.doi.org/10.1159/000499070 Article Text 2019 ftpubmed https://doi.org/10.1159/000499070 2020-03-22T01:17:05Z BACKGROUND: No studies of the prevalence of one of the most common movement disorders, essential tremor (ET), have been undertaken in the Faroe Islands. Given the potential for founder effects in the Islands, and the highly genetic nature of ET, the Faroe Islands provide a particularly interesting setting in which to study the prevalence of ET. OBJECTIVE: To estimate the prevalence of ET and study its characteristics. METHODS: We used a two-phase, population-based design, screening 1,328 randomly-selected Faroese individuals aged ≥40 years. A subsample of 282 individuals who had returned the spirals and questionnaire was selected to participate in an in-person clinical evaluation. Tremor was systematically quantified by a senior movement disorder neurologist with particular specialization in tremor using a reliable and valid clinical rating scale followed by the application of rigorous diagnostic criteria used by tremor investigators internationally. RESULTS: The overall crude prevalence was 2.9%. The age-adjusted prevalence was 3.1%. There was an age-associated rise in prevalence; by age ≥70, prevalence reached 4.80%. Twenty-six of 27 (96.2%) were previously undiagnosed. CONCLUSIONS: This is the first population based-study of the prevalence of ET in the Faroe Islands. The estimated prevalence was similar to studies using the same or comparable methodologies. Text Faroe Islands PubMed Central (PMC) Faroe Islands Neuroepidemiology 52 3-4 227 236 |
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Article Eliasen, Eina H. Ferrer, Monica Gaini, Shahin Louis, Elan D. Petersen, Maria Skaalum Prevalence of Essential Tremor in the Faroe Islands: A Population-Based Study |
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BACKGROUND: No studies of the prevalence of one of the most common movement disorders, essential tremor (ET), have been undertaken in the Faroe Islands. Given the potential for founder effects in the Islands, and the highly genetic nature of ET, the Faroe Islands provide a particularly interesting setting in which to study the prevalence of ET. OBJECTIVE: To estimate the prevalence of ET and study its characteristics. METHODS: We used a two-phase, population-based design, screening 1,328 randomly-selected Faroese individuals aged ≥40 years. A subsample of 282 individuals who had returned the spirals and questionnaire was selected to participate in an in-person clinical evaluation. Tremor was systematically quantified by a senior movement disorder neurologist with particular specialization in tremor using a reliable and valid clinical rating scale followed by the application of rigorous diagnostic criteria used by tremor investigators internationally. RESULTS: The overall crude prevalence was 2.9%. The age-adjusted prevalence was 3.1%. There was an age-associated rise in prevalence; by age ≥70, prevalence reached 4.80%. Twenty-six of 27 (96.2%) were previously undiagnosed. CONCLUSIONS: This is the first population based-study of the prevalence of ET in the Faroe Islands. The estimated prevalence was similar to studies using the same or comparable methodologies. |
format |
Text |
author |
Eliasen, Eina H. Ferrer, Monica Gaini, Shahin Louis, Elan D. Petersen, Maria Skaalum |
author_facet |
Eliasen, Eina H. Ferrer, Monica Gaini, Shahin Louis, Elan D. Petersen, Maria Skaalum |
author_sort |
Eliasen, Eina H. |
title |
Prevalence of Essential Tremor in the Faroe Islands: A Population-Based Study |
title_short |
Prevalence of Essential Tremor in the Faroe Islands: A Population-Based Study |
title_full |
Prevalence of Essential Tremor in the Faroe Islands: A Population-Based Study |
title_fullStr |
Prevalence of Essential Tremor in the Faroe Islands: A Population-Based Study |
title_full_unstemmed |
Prevalence of Essential Tremor in the Faroe Islands: A Population-Based Study |
title_sort |
prevalence of essential tremor in the faroe islands: a population-based study |
publishDate |
2019 |
url |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6626989/ http://www.ncbi.nlm.nih.gov/pubmed/30889566 https://doi.org/10.1159/000499070 |
geographic |
Faroe Islands |
geographic_facet |
Faroe Islands |
genre |
Faroe Islands |
genre_facet |
Faroe Islands |
op_relation |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6626989/ http://www.ncbi.nlm.nih.gov/pubmed/30889566 http://dx.doi.org/10.1159/000499070 |
op_doi |
https://doi.org/10.1159/000499070 |
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Neuroepidemiology |
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52 |
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3-4 |
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227 |
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236 |
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1765995628172673024 |