Anti-aging effects of long-term space missions, estimated by heart rate variability
Reports that aging slows down in space prompted this investigation of anti-aging effects in humans by analyzing astronauts’ heart rate variability (HRV). Ambulatory 48-hour electrocardiograms from 7 astronauts (42.1 ± 6.8 years; 6 men) 20.6 ± 2.7 days (ISS01) and 138.6 ± 21.8 days (ISS02) after laun...
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ftpubmed:oai:pubmedcentral.nih.gov:6586662 2023-05-15T18:33:52+02:00 Anti-aging effects of long-term space missions, estimated by heart rate variability Otsuka, Kuniaki Cornelissen, Germaine Kubo, Yutaka Shibata, Koichi Mizuno, Koh Ohshima, Hiroshi Furukawa, Satoshi Mukai, Chiaki 2019-06-20 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6586662/ http://www.ncbi.nlm.nih.gov/pubmed/31222071 https://doi.org/10.1038/s41598-019-45387-6 en eng Nature Publishing Group UK http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6586662/ http://www.ncbi.nlm.nih.gov/pubmed/31222071 http://dx.doi.org/10.1038/s41598-019-45387-6 © The Author(s) 2019 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. CC-BY Article Text 2019 ftpubmed https://doi.org/10.1038/s41598-019-45387-6 2019-06-30T01:06:35Z Reports that aging slows down in space prompted this investigation of anti-aging effects in humans by analyzing astronauts’ heart rate variability (HRV). Ambulatory 48-hour electrocardiograms from 7 astronauts (42.1 ± 6.8 years; 6 men) 20.6 ± 2.7 days (ISS01) and 138.6 ± 21.8 days (ISS02) after launch were divided into 24-hour spans of relative lower or higher magnetic disturbance, based on geomagnetic measures in Tromso, Norway. Magnetic disturbances were significantly higher on disturbed than on quiet days (ISS01: 72.01 ± 33.82 versus 33.96 ± 17.90 nT, P = 0.0307; ISS02: 71.06 ± 51.52 versus 32.53 ± 27.27 nT, P = 0.0308). SDNNIDX was increased on disturbed days (by 5.5% during ISS01, P = 0.0110), as were other HRV indices during ISS02 (SDANN, 12.5%, P = 0.0243; Triangular Index, 8.4%, P = 0.0469; and TF-component, 17.2%, P = 0.0054), suggesting the action of an anti-aging or longevity effect. The effect on TF was stronger during light (12:00–17:00) than during darkness (0:00–05:00) (P = 0.0268). The brain default mode network (DMN) was activated, gauged by increases in the LF-band (9.7%, P = 0.0730) and MF1-band (9.9%, P = 0.0281). Magnetic changes in the magnetosphere can affect and enhance HRV indices in space, involving an anti-aging or longevity effect, probably in association with the brain DMN, in a light-dependent manner and/or with help from the circadian clock. Text Tromso Tromso PubMed Central (PMC) Norway Tromso ENVELOPE(16.546,16.546,68.801,68.801) Scientific Reports 9 1 |
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Article Otsuka, Kuniaki Cornelissen, Germaine Kubo, Yutaka Shibata, Koichi Mizuno, Koh Ohshima, Hiroshi Furukawa, Satoshi Mukai, Chiaki Anti-aging effects of long-term space missions, estimated by heart rate variability |
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Reports that aging slows down in space prompted this investigation of anti-aging effects in humans by analyzing astronauts’ heart rate variability (HRV). Ambulatory 48-hour electrocardiograms from 7 astronauts (42.1 ± 6.8 years; 6 men) 20.6 ± 2.7 days (ISS01) and 138.6 ± 21.8 days (ISS02) after launch were divided into 24-hour spans of relative lower or higher magnetic disturbance, based on geomagnetic measures in Tromso, Norway. Magnetic disturbances were significantly higher on disturbed than on quiet days (ISS01: 72.01 ± 33.82 versus 33.96 ± 17.90 nT, P = 0.0307; ISS02: 71.06 ± 51.52 versus 32.53 ± 27.27 nT, P = 0.0308). SDNNIDX was increased on disturbed days (by 5.5% during ISS01, P = 0.0110), as were other HRV indices during ISS02 (SDANN, 12.5%, P = 0.0243; Triangular Index, 8.4%, P = 0.0469; and TF-component, 17.2%, P = 0.0054), suggesting the action of an anti-aging or longevity effect. The effect on TF was stronger during light (12:00–17:00) than during darkness (0:00–05:00) (P = 0.0268). The brain default mode network (DMN) was activated, gauged by increases in the LF-band (9.7%, P = 0.0730) and MF1-band (9.9%, P = 0.0281). Magnetic changes in the magnetosphere can affect and enhance HRV indices in space, involving an anti-aging or longevity effect, probably in association with the brain DMN, in a light-dependent manner and/or with help from the circadian clock. |
format |
Text |
author |
Otsuka, Kuniaki Cornelissen, Germaine Kubo, Yutaka Shibata, Koichi Mizuno, Koh Ohshima, Hiroshi Furukawa, Satoshi Mukai, Chiaki |
author_facet |
Otsuka, Kuniaki Cornelissen, Germaine Kubo, Yutaka Shibata, Koichi Mizuno, Koh Ohshima, Hiroshi Furukawa, Satoshi Mukai, Chiaki |
author_sort |
Otsuka, Kuniaki |
title |
Anti-aging effects of long-term space missions, estimated by heart rate variability |
title_short |
Anti-aging effects of long-term space missions, estimated by heart rate variability |
title_full |
Anti-aging effects of long-term space missions, estimated by heart rate variability |
title_fullStr |
Anti-aging effects of long-term space missions, estimated by heart rate variability |
title_full_unstemmed |
Anti-aging effects of long-term space missions, estimated by heart rate variability |
title_sort |
anti-aging effects of long-term space missions, estimated by heart rate variability |
publisher |
Nature Publishing Group UK |
publishDate |
2019 |
url |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6586662/ http://www.ncbi.nlm.nih.gov/pubmed/31222071 https://doi.org/10.1038/s41598-019-45387-6 |
long_lat |
ENVELOPE(16.546,16.546,68.801,68.801) |
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Norway Tromso |
geographic_facet |
Norway Tromso |
genre |
Tromso Tromso |
genre_facet |
Tromso Tromso |
op_relation |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6586662/ http://www.ncbi.nlm.nih.gov/pubmed/31222071 http://dx.doi.org/10.1038/s41598-019-45387-6 |
op_rights |
© The Author(s) 2019 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. |
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CC-BY |
op_doi |
https://doi.org/10.1038/s41598-019-45387-6 |
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