Enzymatic synthesis of lipophilic lutein–PUFA esters and assessment of their stabilization potential in EPA–DHA rich fish oil matrix
The objective of the present study was to synthesize ω-3 polyunsaturated fatty acid esters of lutein and to evaluate if esterification can stabilize the both bioactive molecules. Both ω-3 polyunsaturated fatty acid and lutein are prone towards auto-oxidation in their free form. Free lutein extracted...
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ftpubmed:oai:pubmedcentral.nih.gov:6525738 2023-05-15T14:02:34+02:00 Enzymatic synthesis of lipophilic lutein–PUFA esters and assessment of their stabilization potential in EPA–DHA rich fish oil matrix Dey, Tanmoy Kumar Maiti, Ipshita Chakraborty, Sriparna Ghosh, Mahua Dhar, Pubali 2019-03-25 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6525738/ http://www.ncbi.nlm.nih.gov/pubmed/31168117 https://doi.org/10.1007/s13197-019-03588-x en eng Springer India http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6525738/ http://www.ncbi.nlm.nih.gov/pubmed/31168117 http://dx.doi.org/10.1007/s13197-019-03588-x © Association of Food Scientists & Technologists (India) 2019 Original Article Text 2019 ftpubmed https://doi.org/10.1007/s13197-019-03588-x 2020-05-03T00:22:18Z The objective of the present study was to synthesize ω-3 polyunsaturated fatty acid esters of lutein and to evaluate if esterification can stabilize the both bioactive molecules. Both ω-3 polyunsaturated fatty acid and lutein are prone towards auto-oxidation in their free form. Free lutein extracted from the marigold petals was enzymatically esterified using Candida antarctica NS435 Lipase B, with the ω-3 long-chain polyunsaturated fatty acids. The lutein esters were purified, characterized and finally assessed for their protective role against oxidative degradation in bulk fish oil matrix. The antioxidative effect of these esters was compared with commercial antioxidants of natural origin, i.e., α-tocopherol and a synthetic antioxidant, i.e., tert-butylhydroquinone, at a dosage of 200 mg/L. Both free lutein and lutein–polyunsaturated fatty acid ester had significantly promoted the oxidative stability of bulk fish oil. But based on dose–response relationship, lutein–polyunsaturated fatty acid ester was found to be more efficient than free lutein, in protecting fish oil from secondary oxidation, thereby augmenting their shelf life. Given the high nutraceutical value, potent antioxidative potential and organic origin, it is only relevant to incorporate lutein esters as natural preservative and stabilizers in edible oils. Text Antarc* Antarctica PubMed Central (PMC) Journal of Food Science and Technology 56 5 2345 2354 |
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Original Article Dey, Tanmoy Kumar Maiti, Ipshita Chakraborty, Sriparna Ghosh, Mahua Dhar, Pubali Enzymatic synthesis of lipophilic lutein–PUFA esters and assessment of their stabilization potential in EPA–DHA rich fish oil matrix |
topic_facet |
Original Article |
description |
The objective of the present study was to synthesize ω-3 polyunsaturated fatty acid esters of lutein and to evaluate if esterification can stabilize the both bioactive molecules. Both ω-3 polyunsaturated fatty acid and lutein are prone towards auto-oxidation in their free form. Free lutein extracted from the marigold petals was enzymatically esterified using Candida antarctica NS435 Lipase B, with the ω-3 long-chain polyunsaturated fatty acids. The lutein esters were purified, characterized and finally assessed for their protective role against oxidative degradation in bulk fish oil matrix. The antioxidative effect of these esters was compared with commercial antioxidants of natural origin, i.e., α-tocopherol and a synthetic antioxidant, i.e., tert-butylhydroquinone, at a dosage of 200 mg/L. Both free lutein and lutein–polyunsaturated fatty acid ester had significantly promoted the oxidative stability of bulk fish oil. But based on dose–response relationship, lutein–polyunsaturated fatty acid ester was found to be more efficient than free lutein, in protecting fish oil from secondary oxidation, thereby augmenting their shelf life. Given the high nutraceutical value, potent antioxidative potential and organic origin, it is only relevant to incorporate lutein esters as natural preservative and stabilizers in edible oils. |
format |
Text |
author |
Dey, Tanmoy Kumar Maiti, Ipshita Chakraborty, Sriparna Ghosh, Mahua Dhar, Pubali |
author_facet |
Dey, Tanmoy Kumar Maiti, Ipshita Chakraborty, Sriparna Ghosh, Mahua Dhar, Pubali |
author_sort |
Dey, Tanmoy Kumar |
title |
Enzymatic synthesis of lipophilic lutein–PUFA esters and assessment of their stabilization potential in EPA–DHA rich fish oil matrix |
title_short |
Enzymatic synthesis of lipophilic lutein–PUFA esters and assessment of their stabilization potential in EPA–DHA rich fish oil matrix |
title_full |
Enzymatic synthesis of lipophilic lutein–PUFA esters and assessment of their stabilization potential in EPA–DHA rich fish oil matrix |
title_fullStr |
Enzymatic synthesis of lipophilic lutein–PUFA esters and assessment of their stabilization potential in EPA–DHA rich fish oil matrix |
title_full_unstemmed |
Enzymatic synthesis of lipophilic lutein–PUFA esters and assessment of their stabilization potential in EPA–DHA rich fish oil matrix |
title_sort |
enzymatic synthesis of lipophilic lutein–pufa esters and assessment of their stabilization potential in epa–dha rich fish oil matrix |
publisher |
Springer India |
publishDate |
2019 |
url |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6525738/ http://www.ncbi.nlm.nih.gov/pubmed/31168117 https://doi.org/10.1007/s13197-019-03588-x |
genre |
Antarc* Antarctica |
genre_facet |
Antarc* Antarctica |
op_relation |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6525738/ http://www.ncbi.nlm.nih.gov/pubmed/31168117 http://dx.doi.org/10.1007/s13197-019-03588-x |
op_rights |
© Association of Food Scientists & Technologists (India) 2019 |
op_doi |
https://doi.org/10.1007/s13197-019-03588-x |
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Journal of Food Science and Technology |
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56 |
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5 |
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2345 |
op_container_end_page |
2354 |
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1766272889379618816 |