A closer look at rickets and vitamin D deficiency in Manitoba: The tip of the iceberg
OBJECTIVES: Vitamin D deficiency rickets remains a problem in Canada. Our primary objective was to determine the annual incidence of rickets and/or early vitamin D deficiency in Manitoba. Secondarily, we investigated if there was an increase in the annual incidence. METHODS: A retrospective chart re...
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ftpubmed:oai:pubmedcentral.nih.gov:6519611 2023-05-15T16:55:15+02:00 A closer look at rickets and vitamin D deficiency in Manitoba: The tip of the iceberg Lautatzis, Maria-Elena Sharma, Atul Rodd, Celia 2019-06 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6519611/ http://www.ncbi.nlm.nih.gov/pubmed/31110459 https://doi.org/10.1093/pch/pxy105 en eng Oxford University Press http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6519611/ http://www.ncbi.nlm.nih.gov/pubmed/31110459 http://dx.doi.org/10.1093/pch/pxy105 © The Author(s) 2018. Published by Oxford University Press on behalf of the Canadian Paediatric Society. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com https://academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model This article is published and distributed under the terms of the Oxford University Press, Standard Journals Publication Model (https://academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model) Paediatr Child Health Original Articles Text 2019 ftpubmed https://doi.org/10.1093/pch/pxy105 2020-06-07T00:17:53Z OBJECTIVES: Vitamin D deficiency rickets remains a problem in Canada. Our primary objective was to determine the annual incidence of rickets and/or early vitamin D deficiency in Manitoba. Secondarily, we investigated if there was an increase in the annual incidence. METHODS: A retrospective chart review was undertaken to identify cases in our catchment area from 2003 to 2015. Data sources included endocrine and hospital charts and radiology reports. Early vitamin D deficiency was determined by review of all 25(OH)D tests from 2011 to 2015. Values less than 30 nmol/L with an elevated bone marker prompted a chart review in children under 7 years. RESULTS: We identified 46 cases of rickets and 68 with early vitamin D deficiency. For Manitoba, the annual incidence of rickets was 8.2 cases per 100,000 in infants, and 1.6 per 100,000 in children aged 1 to 7 years. Those with early vitamin D deficiency had annual incidences of 2.7 per 100,000 infants and 9.9 per 100,000 Manitoban children. No temporal trends were noted for either. For both disorders, most cases were from northern or rural locales; about 50% were of self-declared Indigenous or Inuit heritage, and the majority (>75%) of children were from families with high material deprivation using area-based socioeconomic measures. CONCLUSION: Despite several decades of preventative efforts, the incidence of rickets was comparable to previous Canadian reports, particularly in infants. Greater education across the lifespan and engagement with communities and public health agencies will be needed to reduce the high incidence of this preventable disease. Text inuit PubMed Central (PMC) Canada Paediatrics & Child Health 24 3 179 184 |
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Original Articles Lautatzis, Maria-Elena Sharma, Atul Rodd, Celia A closer look at rickets and vitamin D deficiency in Manitoba: The tip of the iceberg |
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Original Articles |
description |
OBJECTIVES: Vitamin D deficiency rickets remains a problem in Canada. Our primary objective was to determine the annual incidence of rickets and/or early vitamin D deficiency in Manitoba. Secondarily, we investigated if there was an increase in the annual incidence. METHODS: A retrospective chart review was undertaken to identify cases in our catchment area from 2003 to 2015. Data sources included endocrine and hospital charts and radiology reports. Early vitamin D deficiency was determined by review of all 25(OH)D tests from 2011 to 2015. Values less than 30 nmol/L with an elevated bone marker prompted a chart review in children under 7 years. RESULTS: We identified 46 cases of rickets and 68 with early vitamin D deficiency. For Manitoba, the annual incidence of rickets was 8.2 cases per 100,000 in infants, and 1.6 per 100,000 in children aged 1 to 7 years. Those with early vitamin D deficiency had annual incidences of 2.7 per 100,000 infants and 9.9 per 100,000 Manitoban children. No temporal trends were noted for either. For both disorders, most cases were from northern or rural locales; about 50% were of self-declared Indigenous or Inuit heritage, and the majority (>75%) of children were from families with high material deprivation using area-based socioeconomic measures. CONCLUSION: Despite several decades of preventative efforts, the incidence of rickets was comparable to previous Canadian reports, particularly in infants. Greater education across the lifespan and engagement with communities and public health agencies will be needed to reduce the high incidence of this preventable disease. |
format |
Text |
author |
Lautatzis, Maria-Elena Sharma, Atul Rodd, Celia |
author_facet |
Lautatzis, Maria-Elena Sharma, Atul Rodd, Celia |
author_sort |
Lautatzis, Maria-Elena |
title |
A closer look at rickets and vitamin D deficiency in Manitoba: The tip of the iceberg |
title_short |
A closer look at rickets and vitamin D deficiency in Manitoba: The tip of the iceberg |
title_full |
A closer look at rickets and vitamin D deficiency in Manitoba: The tip of the iceberg |
title_fullStr |
A closer look at rickets and vitamin D deficiency in Manitoba: The tip of the iceberg |
title_full_unstemmed |
A closer look at rickets and vitamin D deficiency in Manitoba: The tip of the iceberg |
title_sort |
closer look at rickets and vitamin d deficiency in manitoba: the tip of the iceberg |
publisher |
Oxford University Press |
publishDate |
2019 |
url |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6519611/ http://www.ncbi.nlm.nih.gov/pubmed/31110459 https://doi.org/10.1093/pch/pxy105 |
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Canada |
geographic_facet |
Canada |
genre |
inuit |
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inuit |
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Paediatr Child Health |
op_relation |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6519611/ http://www.ncbi.nlm.nih.gov/pubmed/31110459 http://dx.doi.org/10.1093/pch/pxy105 |
op_rights |
© The Author(s) 2018. Published by Oxford University Press on behalf of the Canadian Paediatric Society. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com https://academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model This article is published and distributed under the terms of the Oxford University Press, Standard Journals Publication Model (https://academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model) |
op_doi |
https://doi.org/10.1093/pch/pxy105 |
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Paediatrics & Child Health |
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24 |
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3 |
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179 |
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184 |
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