Genome Organization of Canada Goose Coronavirus, A Novel Species Identified in a Mass Die-off of Canada Geese

The complete genome of a novel coronavirus was sequenced directly from the cloacal swab of a Canada goose that perished in a die-off of Canada and Snow geese in Cambridge Bay, Nunavut, Canada. Comparative genomics and phylogenetic analysis indicate it is a new species of Gammacoronavirus, as it fall...

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Bibliographic Details
Published in:Scientific Reports
Main Authors: Papineau, Amber, Berhane, Yohannes, Wylie, Todd N., Wylie, Kristine M., Sharpe, Samuel, Lung, Oliver
Format: Text
Language:English
Published: Nature Publishing Group UK 2019
Subjects:
Article
Cambridge Bay
Canada
Nunavut
Canada Goose
Online Access:http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6459860/
http://www.ncbi.nlm.nih.gov/pubmed/30976080
https://doi.org/10.1038/s41598-019-42355-y
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Summary:The complete genome of a novel coronavirus was sequenced directly from the cloacal swab of a Canada goose that perished in a die-off of Canada and Snow geese in Cambridge Bay, Nunavut, Canada. Comparative genomics and phylogenetic analysis indicate it is a new species of Gammacoronavirus, as it falls below the threshold of 90% amino acid similarity in the protein domains used to demarcate Coronaviridae. Additional features that distinguish the genome of Canada goose coronavirus include 6 novel ORFs, a partial duplication of the 4 gene and a presumptive change in the proteolytic processing of polyproteins 1a and 1ab.

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