Microbes Producing L-Asparaginase free of Glutaminase and Urease isolated from Extreme Locations of Antarctic Soil and Moss

• Published in: Scientific Reports
• Main Authors: Ashok, Anup, Doriya, Kruthi, Rao, Jyothi Vithal, Qureshi, Asif, Tiwari, Anoop Kumar, Kumar, Devarai Santhosh
• Format: Text
• Language: English
• Published: Nature Publishing Group UK 2019
• Subjects: Article; Antarctic; Dronning Maud Land; Schirmacher Hills; Antarc*; Antarctica
• Online Access: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6363723/; http://www.ncbi.nlm.nih.gov/pubmed/30723240; https://doi.org/10.1038/s41598-018-38094-1

L-Asparaginase (L-asparagine aminohydrolase, E.C. 3.5.1.1) has been proven to be competent in treating Acute Lymphoblastic Leukaemia (ALL), which is widely observed in paediatric and adult groups. Currently, clinical L-Asparaginase formulations are derived from bacterial sources such as Escherichia...