Intestinal Polycyclic Aromatic Hydrocarbon-DNA Adducts in a Population of Beluga Whales with High Levels of Gastrointestinal Cancers

• Published in: Environmental and Molecular Mutagenesis
• Main Authors: Poirier, Miriam C., Lair, Stéphane, Michaud, Robert, Hernández-Ramon, Elena E., Divi, Kathyayini V., Dwyer, Jennifer E., Ester, Corbin D., Si, Nancy N., Ali, Mehnaz, Loseto, Lisa L., Raverty, Stephen A., St. Leger, Judith A., van Bonn, William G., Colegrove, Kathleen, Burek-Huntington, Kathleen A., Suydam, Robert, Stimmelmayr, Raphaela, Wise, John Pierce, Wise, Sandra S., Beauchamp, Guy, Martineau, Daniel
• Format: Text
• Language: English
• Published: 2018
• Subjects: Article; Arctic; Canada; Chukchi Sea; Sea Point; Beaufort Sea; Beluga; Beluga*; Chukchi; Alaska
• Online Access: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320268/; http://www.ncbi.nlm.nih.gov/pubmed/30307653; https://doi.org/10.1002/em.22251

Carcinogenic polycyclic aromatic hydrocarbons (PAHs) were disposed directly into the Saguenay River of the St. Lawrence Estuary (SLE) by local aluminum smelters (Quebec, Canada) for 50 years (1926 to 1976). PAHs in the river sediments are likely etiologically related to gastrointestinal epithelial c...