Population genomics of grey wolves and wolf-like canids in North America
North America is currently home to a number of grey wolf (Canis lupus) and wolf-like canid populations, including the coyote (Canis latrans) and the taxonomically controversial red, Eastern timber and Great Lakes wolves. We explored their population structure and regional gene flow using a dataset o...
Published in: | PLOS Genetics |
---|---|
Main Authors: | , , , , , , , , , , , , , , , , , |
Format: | Text |
Language: | English |
Published: |
Public Library of Science
2018
|
Subjects: | |
Online Access: | http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6231604/ http://www.ncbi.nlm.nih.gov/pubmed/30419012 https://doi.org/10.1371/journal.pgen.1007745 |
id |
ftpubmed:oai:pubmedcentral.nih.gov:6231604 |
---|---|
record_format |
openpolar |
spelling |
ftpubmed:oai:pubmedcentral.nih.gov:6231604 2023-05-15T15:06:31+02:00 Population genomics of grey wolves and wolf-like canids in North America Sinding, Mikkel-Holger S. Gopalakrishan, Shyam Vieira, Filipe G. Samaniego Castruita, Jose A. Raundrup, Katrine Heide Jørgensen, Mads Peter Meldgaard, Morten Petersen, Bent Sicheritz-Ponten, Thomas Mikkelsen, Johan Brus Marquard-Petersen, Ulf Dietz, Rune Sonne, Christian Dalén, Love Bachmann, Lutz Wiig, Øystein Hansen, Anders J. Gilbert, M. Thomas P. 2018-11-12 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6231604/ http://www.ncbi.nlm.nih.gov/pubmed/30419012 https://doi.org/10.1371/journal.pgen.1007745 en eng Public Library of Science http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6231604/ http://www.ncbi.nlm.nih.gov/pubmed/30419012 http://dx.doi.org/10.1371/journal.pgen.1007745 © 2018 Sinding et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. CC-BY Research Article Text 2018 ftpubmed https://doi.org/10.1371/journal.pgen.1007745 2018-11-25T01:22:54Z North America is currently home to a number of grey wolf (Canis lupus) and wolf-like canid populations, including the coyote (Canis latrans) and the taxonomically controversial red, Eastern timber and Great Lakes wolves. We explored their population structure and regional gene flow using a dataset of 40 full genome sequences that represent the extant diversity of North American wolves and wolf-like canid populations. This included 15 new genomes (13 North American grey wolves, 1 red wolf and 1 Eastern timber/Great Lakes wolf), ranging from 0.4 to 15x coverage. In addition to providing full genome support for the previously proposed coyote-wolf admixture origin for the taxonomically controversial red, Eastern timber and Great Lakes wolves, the discriminatory power offered by our dataset suggests all North American grey wolves, including the Mexican form, are monophyletic, and thus share a common ancestor to the exclusion of all other wolves. Furthermore, we identify three distinct populations in the high arctic, one being a previously unidentified “Polar wolf” population endemic to Ellesmere Island and Greenland. Genetic diversity analyses reveal particularly high inbreeding and low heterozygosity in these Polar wolves, consistent with long-term isolation from the other North American wolves. Text Arctic Canis lupus Ellesmere Island Greenland PubMed Central (PMC) Arctic Ellesmere Island Greenland PLOS Genetics 14 11 e1007745 |
institution |
Open Polar |
collection |
PubMed Central (PMC) |
op_collection_id |
ftpubmed |
language |
English |
topic |
Research Article |
spellingShingle |
Research Article Sinding, Mikkel-Holger S. Gopalakrishan, Shyam Vieira, Filipe G. Samaniego Castruita, Jose A. Raundrup, Katrine Heide Jørgensen, Mads Peter Meldgaard, Morten Petersen, Bent Sicheritz-Ponten, Thomas Mikkelsen, Johan Brus Marquard-Petersen, Ulf Dietz, Rune Sonne, Christian Dalén, Love Bachmann, Lutz Wiig, Øystein Hansen, Anders J. Gilbert, M. Thomas P. Population genomics of grey wolves and wolf-like canids in North America |
topic_facet |
Research Article |
description |
North America is currently home to a number of grey wolf (Canis lupus) and wolf-like canid populations, including the coyote (Canis latrans) and the taxonomically controversial red, Eastern timber and Great Lakes wolves. We explored their population structure and regional gene flow using a dataset of 40 full genome sequences that represent the extant diversity of North American wolves and wolf-like canid populations. This included 15 new genomes (13 North American grey wolves, 1 red wolf and 1 Eastern timber/Great Lakes wolf), ranging from 0.4 to 15x coverage. In addition to providing full genome support for the previously proposed coyote-wolf admixture origin for the taxonomically controversial red, Eastern timber and Great Lakes wolves, the discriminatory power offered by our dataset suggests all North American grey wolves, including the Mexican form, are monophyletic, and thus share a common ancestor to the exclusion of all other wolves. Furthermore, we identify three distinct populations in the high arctic, one being a previously unidentified “Polar wolf” population endemic to Ellesmere Island and Greenland. Genetic diversity analyses reveal particularly high inbreeding and low heterozygosity in these Polar wolves, consistent with long-term isolation from the other North American wolves. |
format |
Text |
author |
Sinding, Mikkel-Holger S. Gopalakrishan, Shyam Vieira, Filipe G. Samaniego Castruita, Jose A. Raundrup, Katrine Heide Jørgensen, Mads Peter Meldgaard, Morten Petersen, Bent Sicheritz-Ponten, Thomas Mikkelsen, Johan Brus Marquard-Petersen, Ulf Dietz, Rune Sonne, Christian Dalén, Love Bachmann, Lutz Wiig, Øystein Hansen, Anders J. Gilbert, M. Thomas P. |
author_facet |
Sinding, Mikkel-Holger S. Gopalakrishan, Shyam Vieira, Filipe G. Samaniego Castruita, Jose A. Raundrup, Katrine Heide Jørgensen, Mads Peter Meldgaard, Morten Petersen, Bent Sicheritz-Ponten, Thomas Mikkelsen, Johan Brus Marquard-Petersen, Ulf Dietz, Rune Sonne, Christian Dalén, Love Bachmann, Lutz Wiig, Øystein Hansen, Anders J. Gilbert, M. Thomas P. |
author_sort |
Sinding, Mikkel-Holger S. |
title |
Population genomics of grey wolves and wolf-like canids in North America |
title_short |
Population genomics of grey wolves and wolf-like canids in North America |
title_full |
Population genomics of grey wolves and wolf-like canids in North America |
title_fullStr |
Population genomics of grey wolves and wolf-like canids in North America |
title_full_unstemmed |
Population genomics of grey wolves and wolf-like canids in North America |
title_sort |
population genomics of grey wolves and wolf-like canids in north america |
publisher |
Public Library of Science |
publishDate |
2018 |
url |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6231604/ http://www.ncbi.nlm.nih.gov/pubmed/30419012 https://doi.org/10.1371/journal.pgen.1007745 |
geographic |
Arctic Ellesmere Island Greenland |
geographic_facet |
Arctic Ellesmere Island Greenland |
genre |
Arctic Canis lupus Ellesmere Island Greenland |
genre_facet |
Arctic Canis lupus Ellesmere Island Greenland |
op_relation |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6231604/ http://www.ncbi.nlm.nih.gov/pubmed/30419012 http://dx.doi.org/10.1371/journal.pgen.1007745 |
op_rights |
© 2018 Sinding et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
op_rightsnorm |
CC-BY |
op_doi |
https://doi.org/10.1371/journal.pgen.1007745 |
container_title |
PLOS Genetics |
container_volume |
14 |
container_issue |
11 |
container_start_page |
e1007745 |
_version_ |
1766338111009193984 |