Adipose transcriptome analysis provides novel insights into molecular regulation of prolonged fasting in northern elephant seal pups

• Published in: Physiological Genomics
• Main Authors: Martinez, Bridget, Khudyakov, Jane, Rutherford, Kim, Crocker, Daniel E., Gemmell, Neil, Ortiz, Rudy M.
• Format: Text
• Language: English
• Published: American Physiological Society 2018
• Subjects: Research Article; Nes; Nes’; Elephant Seal; Elephant Seals
• Online Access: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6087879/; http://www.ncbi.nlm.nih.gov/pubmed/29625017; https://doi.org/10.1152/physiolgenomics.00002.2018

The physiological and cellular adaptations to extreme fasting in northern elephant seals (Mirounga angustirostris, NES) are remarkable and may help to elucidate endocrine mechanisms that regulate lipid metabolism and energy homeostasis in mammals. Recent studies have highlighted the importance of th...