Alternatively spliced variants in Atlantic cod (Gadus morhua) support response to variable salinity environment
Analysis of gill transcriptome of the Atlantic cod from the Baltic Sea demonstrated that alternatively spliced (AS) variants may be actively involved in the process of adaptation to altered salinity. Some AS variants of different genes, like phospholipase A2 group IVC (PLA2G4C), appeared only in fis...
Published in: | Scientific Reports |
---|---|
Main Authors: | , , |
Format: | Text |
Language: | English |
Published: |
Nature Publishing Group UK
2018
|
Subjects: | |
Online Access: | http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6072735/ http://www.ncbi.nlm.nih.gov/pubmed/30072755 https://doi.org/10.1038/s41598-018-29723-w |
id |
ftpubmed:oai:pubmedcentral.nih.gov:6072735 |
---|---|
record_format |
openpolar |
spelling |
ftpubmed:oai:pubmedcentral.nih.gov:6072735 2023-05-15T15:27:02+02:00 Alternatively spliced variants in Atlantic cod (Gadus morhua) support response to variable salinity environment Kijewska, Agnieszka Malachowicz, Magdalena Wenne, Roman 2018-08-02 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6072735/ http://www.ncbi.nlm.nih.gov/pubmed/30072755 https://doi.org/10.1038/s41598-018-29723-w en eng Nature Publishing Group UK http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6072735/ http://www.ncbi.nlm.nih.gov/pubmed/30072755 http://dx.doi.org/10.1038/s41598-018-29723-w © The Author(s) 2018 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. CC-BY Article Text 2018 ftpubmed https://doi.org/10.1038/s41598-018-29723-w 2018-08-12T00:26:54Z Analysis of gill transcriptome of the Atlantic cod from the Baltic Sea demonstrated that alternatively spliced (AS) variants may be actively involved in the process of adaptation to altered salinity. Some AS variants of different genes, like phospholipase A2 group IVC (PLA2G4C), appeared only in fish exposed to altered salinity, while other isoforms of the same genes were present in all experimental groups. Novel sequence arrangements represent 89% of all AS in the Baltic cod compared to the Atlantic population. Profiles of modified pathways suggest that regulation by AS can afford specific changes of genes expressed in response to the environment. The AS variants appear to be involved in the response to stress by modifications of signalling in apoptosis pathways, an innate immunological response and pro-inflammatory process. Present results support the hypothesis that developing new AS variants could support genome complexity and reinforce the ability to fast adapt to local environments. Text atlantic cod Gadus morhua PubMed Central (PMC) Scientific Reports 8 1 |
institution |
Open Polar |
collection |
PubMed Central (PMC) |
op_collection_id |
ftpubmed |
language |
English |
topic |
Article |
spellingShingle |
Article Kijewska, Agnieszka Malachowicz, Magdalena Wenne, Roman Alternatively spliced variants in Atlantic cod (Gadus morhua) support response to variable salinity environment |
topic_facet |
Article |
description |
Analysis of gill transcriptome of the Atlantic cod from the Baltic Sea demonstrated that alternatively spliced (AS) variants may be actively involved in the process of adaptation to altered salinity. Some AS variants of different genes, like phospholipase A2 group IVC (PLA2G4C), appeared only in fish exposed to altered salinity, while other isoforms of the same genes were present in all experimental groups. Novel sequence arrangements represent 89% of all AS in the Baltic cod compared to the Atlantic population. Profiles of modified pathways suggest that regulation by AS can afford specific changes of genes expressed in response to the environment. The AS variants appear to be involved in the response to stress by modifications of signalling in apoptosis pathways, an innate immunological response and pro-inflammatory process. Present results support the hypothesis that developing new AS variants could support genome complexity and reinforce the ability to fast adapt to local environments. |
format |
Text |
author |
Kijewska, Agnieszka Malachowicz, Magdalena Wenne, Roman |
author_facet |
Kijewska, Agnieszka Malachowicz, Magdalena Wenne, Roman |
author_sort |
Kijewska, Agnieszka |
title |
Alternatively spliced variants in Atlantic cod (Gadus morhua) support response to variable salinity environment |
title_short |
Alternatively spliced variants in Atlantic cod (Gadus morhua) support response to variable salinity environment |
title_full |
Alternatively spliced variants in Atlantic cod (Gadus morhua) support response to variable salinity environment |
title_fullStr |
Alternatively spliced variants in Atlantic cod (Gadus morhua) support response to variable salinity environment |
title_full_unstemmed |
Alternatively spliced variants in Atlantic cod (Gadus morhua) support response to variable salinity environment |
title_sort |
alternatively spliced variants in atlantic cod (gadus morhua) support response to variable salinity environment |
publisher |
Nature Publishing Group UK |
publishDate |
2018 |
url |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6072735/ http://www.ncbi.nlm.nih.gov/pubmed/30072755 https://doi.org/10.1038/s41598-018-29723-w |
genre |
atlantic cod Gadus morhua |
genre_facet |
atlantic cod Gadus morhua |
op_relation |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6072735/ http://www.ncbi.nlm.nih.gov/pubmed/30072755 http://dx.doi.org/10.1038/s41598-018-29723-w |
op_rights |
© The Author(s) 2018 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. |
op_rightsnorm |
CC-BY |
op_doi |
https://doi.org/10.1038/s41598-018-29723-w |
container_title |
Scientific Reports |
container_volume |
8 |
container_issue |
1 |
_version_ |
1766357504894173184 |