Effects of Frozen Storage on Phospholipid Content in Atlantic Cod Fillets and the Influence on Diet-Induced Obesity in Mice
A large fraction of the n-3 polyunsaturated fatty acids (PUFAs) in cod fillet is present in the form of phospholipids (PLs). Freezing initiates hydrolysis of the PLs present in the fillet. Here, we compared the effects of Western diets based on frozen cod, fresh cod or pork with a diet based on case...
Published in: | Nutrients |
---|---|
Main Authors: | , , , , , , , |
Format: | Text |
Language: | English |
Published: |
MDPI
2018
|
Subjects: | |
Online Access: | http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6024676/ http://www.ncbi.nlm.nih.gov/pubmed/29848963 https://doi.org/10.3390/nu10060695 |
id |
ftpubmed:oai:pubmedcentral.nih.gov:6024676 |
---|---|
record_format |
openpolar |
spelling |
ftpubmed:oai:pubmedcentral.nih.gov:6024676 2023-05-15T15:27:38+02:00 Effects of Frozen Storage on Phospholipid Content in Atlantic Cod Fillets and the Influence on Diet-Induced Obesity in Mice Fauske, Kristin Røen Bernhard, Annette Fjære, Even Myrmel, Lene Secher Frøyland, Livar Kristiansen, Karsten Liaset, Bjørn Madsen, Lise 2018-05-30 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6024676/ http://www.ncbi.nlm.nih.gov/pubmed/29848963 https://doi.org/10.3390/nu10060695 en eng MDPI http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6024676/ http://www.ncbi.nlm.nih.gov/pubmed/29848963 http://dx.doi.org/10.3390/nu10060695 © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). CC-BY Article Text 2018 ftpubmed https://doi.org/10.3390/nu10060695 2018-07-15T00:14:15Z A large fraction of the n-3 polyunsaturated fatty acids (PUFAs) in cod fillet is present in the form of phospholipids (PLs). Freezing initiates hydrolysis of the PLs present in the fillet. Here, we compared the effects of Western diets based on frozen cod, fresh cod or pork with a diet based on casein in male C57BL/6J mice fed for 12 weeks at thermoneutrality. Diets based on fresh cod contained more PL-bound n-3 PUFAs (3.12 mg/g diet) than diets based on frozen cod (1.9 mg/g diet). Mice fed diets containing pork and fresh cod, but not frozen cod, gained more body and fat mass than casein-fed mice. Additionally, the bioavailability of n-3 PUFAs present in the cod fillets was not influenced by storage conditions. In a second experiment, diets with pork as the protein source were supplemented with n-3 PUFAs in the form of PL or triacylglycerol (TAG) to match the levels of the diet containing fresh cod. Adding PL-bound, but not TAG-bound, n-3 PUFAs, to the pork-based diet increased body and fat mass gain. Thus, supplementation with PL-bound n-3 PUFAs did not protect against, but rather promoted, obesity development in mice fed a pork-based diet. Text atlantic cod PubMed Central (PMC) Nutrients 10 6 695 |
institution |
Open Polar |
collection |
PubMed Central (PMC) |
op_collection_id |
ftpubmed |
language |
English |
topic |
Article |
spellingShingle |
Article Fauske, Kristin Røen Bernhard, Annette Fjære, Even Myrmel, Lene Secher Frøyland, Livar Kristiansen, Karsten Liaset, Bjørn Madsen, Lise Effects of Frozen Storage on Phospholipid Content in Atlantic Cod Fillets and the Influence on Diet-Induced Obesity in Mice |
topic_facet |
Article |
description |
A large fraction of the n-3 polyunsaturated fatty acids (PUFAs) in cod fillet is present in the form of phospholipids (PLs). Freezing initiates hydrolysis of the PLs present in the fillet. Here, we compared the effects of Western diets based on frozen cod, fresh cod or pork with a diet based on casein in male C57BL/6J mice fed for 12 weeks at thermoneutrality. Diets based on fresh cod contained more PL-bound n-3 PUFAs (3.12 mg/g diet) than diets based on frozen cod (1.9 mg/g diet). Mice fed diets containing pork and fresh cod, but not frozen cod, gained more body and fat mass than casein-fed mice. Additionally, the bioavailability of n-3 PUFAs present in the cod fillets was not influenced by storage conditions. In a second experiment, diets with pork as the protein source were supplemented with n-3 PUFAs in the form of PL or triacylglycerol (TAG) to match the levels of the diet containing fresh cod. Adding PL-bound, but not TAG-bound, n-3 PUFAs, to the pork-based diet increased body and fat mass gain. Thus, supplementation with PL-bound n-3 PUFAs did not protect against, but rather promoted, obesity development in mice fed a pork-based diet. |
format |
Text |
author |
Fauske, Kristin Røen Bernhard, Annette Fjære, Even Myrmel, Lene Secher Frøyland, Livar Kristiansen, Karsten Liaset, Bjørn Madsen, Lise |
author_facet |
Fauske, Kristin Røen Bernhard, Annette Fjære, Even Myrmel, Lene Secher Frøyland, Livar Kristiansen, Karsten Liaset, Bjørn Madsen, Lise |
author_sort |
Fauske, Kristin Røen |
title |
Effects of Frozen Storage on Phospholipid Content in Atlantic Cod Fillets and the Influence on Diet-Induced Obesity in Mice |
title_short |
Effects of Frozen Storage on Phospholipid Content in Atlantic Cod Fillets and the Influence on Diet-Induced Obesity in Mice |
title_full |
Effects of Frozen Storage on Phospholipid Content in Atlantic Cod Fillets and the Influence on Diet-Induced Obesity in Mice |
title_fullStr |
Effects of Frozen Storage on Phospholipid Content in Atlantic Cod Fillets and the Influence on Diet-Induced Obesity in Mice |
title_full_unstemmed |
Effects of Frozen Storage on Phospholipid Content in Atlantic Cod Fillets and the Influence on Diet-Induced Obesity in Mice |
title_sort |
effects of frozen storage on phospholipid content in atlantic cod fillets and the influence on diet-induced obesity in mice |
publisher |
MDPI |
publishDate |
2018 |
url |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6024676/ http://www.ncbi.nlm.nih.gov/pubmed/29848963 https://doi.org/10.3390/nu10060695 |
genre |
atlantic cod |
genre_facet |
atlantic cod |
op_relation |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6024676/ http://www.ncbi.nlm.nih.gov/pubmed/29848963 http://dx.doi.org/10.3390/nu10060695 |
op_rights |
© 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
op_rightsnorm |
CC-BY |
op_doi |
https://doi.org/10.3390/nu10060695 |
container_title |
Nutrients |
container_volume |
10 |
container_issue |
6 |
container_start_page |
695 |
_version_ |
1766358051849240576 |