Evolution of Sex Determination Loci in Atlantic Salmon
Teleost fish exhibit a remarkable diversity in the control of sex determination, offering the opportunity to identify novel differentiation mechanisms and their ecological consequences. Here, we perform GWAS using 4715 fish and 46,501 SNP to map sex determination to three separate genomic locations...
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ftpubmed:oai:pubmedcentral.nih.gov:5884791 2023-05-15T15:30:59+02:00 Evolution of Sex Determination Loci in Atlantic Salmon Kijas, James McWilliam, Sean Naval Sanchez, Marina Kube, Peter King, Harry Evans, Bradley Nome, Torfinn Lien, Sigbjørn Verbyla, Klara 2018-04-04 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884791/ http://www.ncbi.nlm.nih.gov/pubmed/29618750 https://doi.org/10.1038/s41598-018-23984-1 en eng Nature Publishing Group UK http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884791/ http://www.ncbi.nlm.nih.gov/pubmed/29618750 http://dx.doi.org/10.1038/s41598-018-23984-1 © The Author(s) 2018 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. CC-BY Article Text 2018 ftpubmed https://doi.org/10.1038/s41598-018-23984-1 2018-04-22T01:10:34Z Teleost fish exhibit a remarkable diversity in the control of sex determination, offering the opportunity to identify novel differentiation mechanisms and their ecological consequences. Here, we perform GWAS using 4715 fish and 46,501 SNP to map sex determination to three separate genomic locations in Atlantic salmon (Salmo salar). To characterize each, whole genome sequencing was performed to 30-fold depth of coverage using 20 fish representing each of three identified sex lineages. SNP polymorphism reveals male fish carry a single copy of the male specific region, consistent with an XX/XY or male heterogametric sex system. Haplotype analysis revealed deep divergence between the putatively ancestral locus on chromosome 2, compared with loci on chromosomes 3 and 6. Haplotypes in fish carrying either the chromosome 3 or 6 loci were nearly indistinguishable, indicating a founding event that occurred following the speciation event that defined Salmo salar from other salmonids. These findings highlight the evolutionarily fluid state of sex determination systems in salmonids, and resolve to the sequence level differences in animals with divergent sex lineages. Text Atlantic salmon Salmo salar PubMed Central (PMC) Scientific Reports 8 1 |
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Article Kijas, James McWilliam, Sean Naval Sanchez, Marina Kube, Peter King, Harry Evans, Bradley Nome, Torfinn Lien, Sigbjørn Verbyla, Klara Evolution of Sex Determination Loci in Atlantic Salmon |
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Article |
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Teleost fish exhibit a remarkable diversity in the control of sex determination, offering the opportunity to identify novel differentiation mechanisms and their ecological consequences. Here, we perform GWAS using 4715 fish and 46,501 SNP to map sex determination to three separate genomic locations in Atlantic salmon (Salmo salar). To characterize each, whole genome sequencing was performed to 30-fold depth of coverage using 20 fish representing each of three identified sex lineages. SNP polymorphism reveals male fish carry a single copy of the male specific region, consistent with an XX/XY or male heterogametric sex system. Haplotype analysis revealed deep divergence between the putatively ancestral locus on chromosome 2, compared with loci on chromosomes 3 and 6. Haplotypes in fish carrying either the chromosome 3 or 6 loci were nearly indistinguishable, indicating a founding event that occurred following the speciation event that defined Salmo salar from other salmonids. These findings highlight the evolutionarily fluid state of sex determination systems in salmonids, and resolve to the sequence level differences in animals with divergent sex lineages. |
format |
Text |
author |
Kijas, James McWilliam, Sean Naval Sanchez, Marina Kube, Peter King, Harry Evans, Bradley Nome, Torfinn Lien, Sigbjørn Verbyla, Klara |
author_facet |
Kijas, James McWilliam, Sean Naval Sanchez, Marina Kube, Peter King, Harry Evans, Bradley Nome, Torfinn Lien, Sigbjørn Verbyla, Klara |
author_sort |
Kijas, James |
title |
Evolution of Sex Determination Loci in Atlantic Salmon |
title_short |
Evolution of Sex Determination Loci in Atlantic Salmon |
title_full |
Evolution of Sex Determination Loci in Atlantic Salmon |
title_fullStr |
Evolution of Sex Determination Loci in Atlantic Salmon |
title_full_unstemmed |
Evolution of Sex Determination Loci in Atlantic Salmon |
title_sort |
evolution of sex determination loci in atlantic salmon |
publisher |
Nature Publishing Group UK |
publishDate |
2018 |
url |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884791/ http://www.ncbi.nlm.nih.gov/pubmed/29618750 https://doi.org/10.1038/s41598-018-23984-1 |
genre |
Atlantic salmon Salmo salar |
genre_facet |
Atlantic salmon Salmo salar |
op_relation |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884791/ http://www.ncbi.nlm.nih.gov/pubmed/29618750 http://dx.doi.org/10.1038/s41598-018-23984-1 |
op_rights |
© The Author(s) 2018 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. |
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CC-BY |
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https://doi.org/10.1038/s41598-018-23984-1 |
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Scientific Reports |
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