Variability of cancer risk within an area: time to complement the incidence rate
The aim of this study was to show that age-adjusted cancer incidence rates for an area may not be representative of the incidence in subareas. We propose a simple measure to show the amount of geographical variability. European age-standardized incidence rates (ASRs) for ‘all sites excluding nonmela...
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ftpubmed:oai:pubmedcentral.nih.gov:5647116 2023-05-15T16:10:58+02:00 Variability of cancer risk within an area: time to complement the incidence rate Crocetti, Emanuele Giusti, Francesco Martos, Carmen Randi, Giorgia Dyba, Tadeusz Bettio, Manola 2017-09 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5647116/ http://www.ncbi.nlm.nih.gov/pubmed/28654436 https://doi.org/10.1097/CEJ.0000000000000389 en eng Lippincott Williams & Wilkins http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5647116/ http://www.ncbi.nlm.nih.gov/pubmed/28654436 http://dx.doi.org/10.1097/CEJ.0000000000000389 Copyright © 2017 Wolters Kluwer Health, Inc. All rights reserved. This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (http://creativecommons.org/licenses/by-nc-nd/4.0/) (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc-nd/4.0/ CC-BY-NC-ND Research Papers: Epidemiology Text 2017 ftpubmed https://doi.org/10.1097/CEJ.0000000000000389 2017-11-05T01:25:39Z The aim of this study was to show that age-adjusted cancer incidence rates for an area may not be representative of the incidence in subareas. We propose a simple measure to show the amount of geographical variability. European age-standardized incidence rates (ASRs) for ‘all sites excluding nonmelanoma skin cancer’, for men, in 2014, for Nordic countries as a whole, for each country (Denmark, Faroe Islands, Finland, Greenland, Iceland, Sweden and Norway) and for their regions, were retrieved from the Nordcan with corresponding standard errors SEs. We compared the ASR for Nordic countries versus single country and single country versus specific regions. The overlapping of 95% confidence intervals was used for ASRs comparisons. As a measure of variability, we computed the range between the highest and the lowest ASR within an area and the ratio between this range and the ASR of the overall area, r/R=(range/ASR)×100. The 95% confidence interval of the ASR for Nordic countries as a whole did not overlap those of the majority of the single countries; in fact, the r/R – which provides a clue for the amount of underlying geographical variability – was rather large (57.1%). Within countries, the variability was negligible in Iceland (r/R=9.6%), whereas the highest value was found in Sweden (37.1%). The ASR does not provide any information on underlying geographical variability. Therefore, its interpretation could be misleading. When data for subareas are available, the r/R, which is simple to compute and to understand, should be added to the ASR for providing more truthful information. Text Faroe Islands Greenland Iceland PubMed Central (PMC) Faroe Islands Greenland Norway European Journal of Cancer Prevention 26 5 442 446 |
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topic |
Research Papers: Epidemiology |
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Research Papers: Epidemiology Crocetti, Emanuele Giusti, Francesco Martos, Carmen Randi, Giorgia Dyba, Tadeusz Bettio, Manola Variability of cancer risk within an area: time to complement the incidence rate |
topic_facet |
Research Papers: Epidemiology |
description |
The aim of this study was to show that age-adjusted cancer incidence rates for an area may not be representative of the incidence in subareas. We propose a simple measure to show the amount of geographical variability. European age-standardized incidence rates (ASRs) for ‘all sites excluding nonmelanoma skin cancer’, for men, in 2014, for Nordic countries as a whole, for each country (Denmark, Faroe Islands, Finland, Greenland, Iceland, Sweden and Norway) and for their regions, were retrieved from the Nordcan with corresponding standard errors SEs. We compared the ASR for Nordic countries versus single country and single country versus specific regions. The overlapping of 95% confidence intervals was used for ASRs comparisons. As a measure of variability, we computed the range between the highest and the lowest ASR within an area and the ratio between this range and the ASR of the overall area, r/R=(range/ASR)×100. The 95% confidence interval of the ASR for Nordic countries as a whole did not overlap those of the majority of the single countries; in fact, the r/R – which provides a clue for the amount of underlying geographical variability – was rather large (57.1%). Within countries, the variability was negligible in Iceland (r/R=9.6%), whereas the highest value was found in Sweden (37.1%). The ASR does not provide any information on underlying geographical variability. Therefore, its interpretation could be misleading. When data for subareas are available, the r/R, which is simple to compute and to understand, should be added to the ASR for providing more truthful information. |
format |
Text |
author |
Crocetti, Emanuele Giusti, Francesco Martos, Carmen Randi, Giorgia Dyba, Tadeusz Bettio, Manola |
author_facet |
Crocetti, Emanuele Giusti, Francesco Martos, Carmen Randi, Giorgia Dyba, Tadeusz Bettio, Manola |
author_sort |
Crocetti, Emanuele |
title |
Variability of cancer risk within an area: time to complement the incidence rate |
title_short |
Variability of cancer risk within an area: time to complement the incidence rate |
title_full |
Variability of cancer risk within an area: time to complement the incidence rate |
title_fullStr |
Variability of cancer risk within an area: time to complement the incidence rate |
title_full_unstemmed |
Variability of cancer risk within an area: time to complement the incidence rate |
title_sort |
variability of cancer risk within an area: time to complement the incidence rate |
publisher |
Lippincott Williams & Wilkins |
publishDate |
2017 |
url |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5647116/ http://www.ncbi.nlm.nih.gov/pubmed/28654436 https://doi.org/10.1097/CEJ.0000000000000389 |
geographic |
Faroe Islands Greenland Norway |
geographic_facet |
Faroe Islands Greenland Norway |
genre |
Faroe Islands Greenland Iceland |
genre_facet |
Faroe Islands Greenland Iceland |
op_relation |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5647116/ http://www.ncbi.nlm.nih.gov/pubmed/28654436 http://dx.doi.org/10.1097/CEJ.0000000000000389 |
op_rights |
Copyright © 2017 Wolters Kluwer Health, Inc. All rights reserved. This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (http://creativecommons.org/licenses/by-nc-nd/4.0/) (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc-nd/4.0/ |
op_rightsnorm |
CC-BY-NC-ND |
op_doi |
https://doi.org/10.1097/CEJ.0000000000000389 |
container_title |
European Journal of Cancer Prevention |
container_volume |
26 |
container_issue |
5 |
container_start_page |
442 |
op_container_end_page |
446 |
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1765996092187475968 |