Prevalence of influenza A virus in live-captured North Atlantic gray seals: a possible wild reservoir
Influenza A virus (IAV) has been associated with multiple unusual mortality events (UMEs) in North Atlantic pinnipeds, frequently attributed to spillover of virus from wild-bird reservoirs. To determine if endemic infection persists outside of UMEs, we undertook a multiyear investigation of IAV in h...
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ftpubmed:oai:pubmedcentral.nih.gov:5034098 2023-05-15T17:29:54+02:00 Prevalence of influenza A virus in live-captured North Atlantic gray seals: a possible wild reservoir Puryear, Wendy Blay Keogh, Mandy Hill, Nichola Moxley, Jerry Josephson, Elizabeth Davis, Kimberly Ryan Bandoro, Chistopher Lidgard, Damian Bogomolni, Andrea Levin, Milton Lang, Shelley Hammill, Michael Bowen, Don Johnston, David W Romano, Tracy Waring, Gordon Runstadler, Jonathan 2016-08 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5034098/ http://www.ncbi.nlm.nih.gov/pubmed/27485496 https://doi.org/10.1038/emi.2016.77 en eng Nature Publishing Group http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5034098/ http://www.ncbi.nlm.nih.gov/pubmed/27485496 http://dx.doi.org/10.1038/emi.2016.77 Copyright © 2016 The Author(s) http://creativecommons.org/licenses/by/4.0/ This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article's Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ CC-BY Original Article Text 2016 ftpubmed https://doi.org/10.1038/emi.2016.77 2016-10-09T00:06:41Z Influenza A virus (IAV) has been associated with multiple unusual mortality events (UMEs) in North Atlantic pinnipeds, frequently attributed to spillover of virus from wild-bird reservoirs. To determine if endemic infection persists outside of UMEs, we undertook a multiyear investigation of IAV in healthy, live-captured Northwest Atlantic gray seals (Halichoerus grypus). From 2013 to 2015, we sampled 345 pups and 57 adults from Cape Cod, MA, USA and Nova Scotia, Canada consistently detecting IAV infection across all groups. There was an overall viral prevalence of 9.0% (95% confidence interval (CI): 6.4%–12.5%) in weaned pups and 5.3% (CI: 1.2%–14.6%) in adults, with seroprevalences of 19.3% (CI: 15.0%–24.5%) and 50% (CI: 33.7%–66.4%), respectively. Positive sera showed a broad reactivity to diverse influenza subtypes. IAV status did not correlate with measures of animal health nor impact animal movement or foraging. This study demonstrated that Northwest Atlantic gray seals are both permissive to and tolerant of diverse IAV, possibly representing an endemically infected wild reservoir population. Text North Atlantic Northwest Atlantic PubMed Central (PMC) Canada Emerging Microbes & Infections 5 1 1 9 |
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Original Article Puryear, Wendy Blay Keogh, Mandy Hill, Nichola Moxley, Jerry Josephson, Elizabeth Davis, Kimberly Ryan Bandoro, Chistopher Lidgard, Damian Bogomolni, Andrea Levin, Milton Lang, Shelley Hammill, Michael Bowen, Don Johnston, David W Romano, Tracy Waring, Gordon Runstadler, Jonathan Prevalence of influenza A virus in live-captured North Atlantic gray seals: a possible wild reservoir |
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Original Article |
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Influenza A virus (IAV) has been associated with multiple unusual mortality events (UMEs) in North Atlantic pinnipeds, frequently attributed to spillover of virus from wild-bird reservoirs. To determine if endemic infection persists outside of UMEs, we undertook a multiyear investigation of IAV in healthy, live-captured Northwest Atlantic gray seals (Halichoerus grypus). From 2013 to 2015, we sampled 345 pups and 57 adults from Cape Cod, MA, USA and Nova Scotia, Canada consistently detecting IAV infection across all groups. There was an overall viral prevalence of 9.0% (95% confidence interval (CI): 6.4%–12.5%) in weaned pups and 5.3% (CI: 1.2%–14.6%) in adults, with seroprevalences of 19.3% (CI: 15.0%–24.5%) and 50% (CI: 33.7%–66.4%), respectively. Positive sera showed a broad reactivity to diverse influenza subtypes. IAV status did not correlate with measures of animal health nor impact animal movement or foraging. This study demonstrated that Northwest Atlantic gray seals are both permissive to and tolerant of diverse IAV, possibly representing an endemically infected wild reservoir population. |
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Text |
author |
Puryear, Wendy Blay Keogh, Mandy Hill, Nichola Moxley, Jerry Josephson, Elizabeth Davis, Kimberly Ryan Bandoro, Chistopher Lidgard, Damian Bogomolni, Andrea Levin, Milton Lang, Shelley Hammill, Michael Bowen, Don Johnston, David W Romano, Tracy Waring, Gordon Runstadler, Jonathan |
author_facet |
Puryear, Wendy Blay Keogh, Mandy Hill, Nichola Moxley, Jerry Josephson, Elizabeth Davis, Kimberly Ryan Bandoro, Chistopher Lidgard, Damian Bogomolni, Andrea Levin, Milton Lang, Shelley Hammill, Michael Bowen, Don Johnston, David W Romano, Tracy Waring, Gordon Runstadler, Jonathan |
author_sort |
Puryear, Wendy Blay |
title |
Prevalence of influenza A virus in live-captured North Atlantic gray seals: a possible wild reservoir |
title_short |
Prevalence of influenza A virus in live-captured North Atlantic gray seals: a possible wild reservoir |
title_full |
Prevalence of influenza A virus in live-captured North Atlantic gray seals: a possible wild reservoir |
title_fullStr |
Prevalence of influenza A virus in live-captured North Atlantic gray seals: a possible wild reservoir |
title_full_unstemmed |
Prevalence of influenza A virus in live-captured North Atlantic gray seals: a possible wild reservoir |
title_sort |
prevalence of influenza a virus in live-captured north atlantic gray seals: a possible wild reservoir |
publisher |
Nature Publishing Group |
publishDate |
2016 |
url |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5034098/ http://www.ncbi.nlm.nih.gov/pubmed/27485496 https://doi.org/10.1038/emi.2016.77 |
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Canada |
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Canada |
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North Atlantic Northwest Atlantic |
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North Atlantic Northwest Atlantic |
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5034098/ http://www.ncbi.nlm.nih.gov/pubmed/27485496 http://dx.doi.org/10.1038/emi.2016.77 |
op_rights |
Copyright © 2016 The Author(s) http://creativecommons.org/licenses/by/4.0/ This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article's Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ |
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CC-BY |
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https://doi.org/10.1038/emi.2016.77 |
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Emerging Microbes & Infections |
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5 |
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9 |
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