Light and temperature effects on bioactivity in diatoms
Isolates of five pelagic North Atlantic marine diatoms (Bacillariophyceae): Attheya longicornis, Chaetoceros socialis, Chaetoceros furcellatus, Skeletonema marinoi and Porosira glacialis were cultivated in large photobioreactors at two light and two temperature regimes to test if this affected bioac...
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ftpubmed:oai:pubmedcentral.nih.gov:4789199 2023-05-15T17:31:46+02:00 Light and temperature effects on bioactivity in diatoms Ingebrigtsen, Richard A. Hansen, Espen Andersen, Jeanette Hammer Eilertsen, Hans Christian 2015-06-05 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4789199/ https://doi.org/10.1007/s10811-015-0631-4 en eng Springer Netherlands http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4789199/ http://dx.doi.org/10.1007/s10811-015-0631-4 © The Author(s) 2015 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. CC-BY Article Text 2015 ftpubmed https://doi.org/10.1007/s10811-015-0631-4 2016-04-10T00:04:26Z Isolates of five pelagic North Atlantic marine diatoms (Bacillariophyceae): Attheya longicornis, Chaetoceros socialis, Chaetoceros furcellatus, Skeletonema marinoi and Porosira glacialis were cultivated in large photobioreactors at two light and two temperature regimes to test if this affected bioactivity. We screened for bioactivity in assays representing five different therapeutic areas: diabetes II (PTP1b), cancer (melanoma cells, A2058), anti-oxidants (FRAP), immunomodulation (TNFa) and anti-infection (MRSA, Enterococcus faecalis, Staphylococcus aureus, Escherichia coli and Pseudomonas aeruginosa). All the diatom strains showed activity in two or more assays. We detected differences in bioactivity both between species and within species cultivated with different light and temperature regimes. Our results demonstrate the potential for a more exhaustive exploitation of diatom metabolites that can be obtained by manipulation of the cultivation conditions. Text North Atlantic PubMed Central (PMC) Journal of Applied Phycology 28 2 939 950 |
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Article Ingebrigtsen, Richard A. Hansen, Espen Andersen, Jeanette Hammer Eilertsen, Hans Christian Light and temperature effects on bioactivity in diatoms |
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Article |
description |
Isolates of five pelagic North Atlantic marine diatoms (Bacillariophyceae): Attheya longicornis, Chaetoceros socialis, Chaetoceros furcellatus, Skeletonema marinoi and Porosira glacialis were cultivated in large photobioreactors at two light and two temperature regimes to test if this affected bioactivity. We screened for bioactivity in assays representing five different therapeutic areas: diabetes II (PTP1b), cancer (melanoma cells, A2058), anti-oxidants (FRAP), immunomodulation (TNFa) and anti-infection (MRSA, Enterococcus faecalis, Staphylococcus aureus, Escherichia coli and Pseudomonas aeruginosa). All the diatom strains showed activity in two or more assays. We detected differences in bioactivity both between species and within species cultivated with different light and temperature regimes. Our results demonstrate the potential for a more exhaustive exploitation of diatom metabolites that can be obtained by manipulation of the cultivation conditions. |
format |
Text |
author |
Ingebrigtsen, Richard A. Hansen, Espen Andersen, Jeanette Hammer Eilertsen, Hans Christian |
author_facet |
Ingebrigtsen, Richard A. Hansen, Espen Andersen, Jeanette Hammer Eilertsen, Hans Christian |
author_sort |
Ingebrigtsen, Richard A. |
title |
Light and temperature effects on bioactivity in diatoms |
title_short |
Light and temperature effects on bioactivity in diatoms |
title_full |
Light and temperature effects on bioactivity in diatoms |
title_fullStr |
Light and temperature effects on bioactivity in diatoms |
title_full_unstemmed |
Light and temperature effects on bioactivity in diatoms |
title_sort |
light and temperature effects on bioactivity in diatoms |
publisher |
Springer Netherlands |
publishDate |
2015 |
url |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4789199/ https://doi.org/10.1007/s10811-015-0631-4 |
genre |
North Atlantic |
genre_facet |
North Atlantic |
op_relation |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4789199/ http://dx.doi.org/10.1007/s10811-015-0631-4 |
op_rights |
© The Author(s) 2015 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. |
op_rightsnorm |
CC-BY |
op_doi |
https://doi.org/10.1007/s10811-015-0631-4 |
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Journal of Applied Phycology |
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28 |
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2 |
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939 |
op_container_end_page |
950 |
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1766129517702676480 |