Exposure to the Paralytic Shellfish Toxin Producer Alexandrium catenella Increases the Susceptibility of the Oyster Crassostrea gigas to Pathogenic Vibrios
The multifactorial etiology of massive Crassostrea gigas summer mortalities results from complex interactions between oysters, opportunistic pathogens and environmental factors. In a field survey conducted in 2014 in the Mediterranean Thau Lagoon (France), we evidenced that the development of the to...
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ftpubmed:oai:pubmedcentral.nih.gov:4728546 2023-05-15T15:57:40+02:00 Exposure to the Paralytic Shellfish Toxin Producer Alexandrium catenella Increases the Susceptibility of the Oyster Crassostrea gigas to Pathogenic Vibrios Abi-Khalil, Celina Lopez-Joven, Carmen Abadie, Eric Savar, Veronique Amzil, Zouher Laabir, Mohamed Rolland, Jean-Luc 2016-01-15 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4728546/ http://www.ncbi.nlm.nih.gov/pubmed/26784228 https://doi.org/10.3390/toxins8010024 en eng MDPI http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4728546/ http://www.ncbi.nlm.nih.gov/pubmed/26784228 http://dx.doi.org/10.3390/toxins8010024 © 2016 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons by Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/). CC-BY Article Text 2016 ftpubmed https://doi.org/10.3390/toxins8010024 2016-02-14T01:01:43Z The multifactorial etiology of massive Crassostrea gigas summer mortalities results from complex interactions between oysters, opportunistic pathogens and environmental factors. In a field survey conducted in 2014 in the Mediterranean Thau Lagoon (France), we evidenced that the development of the toxic dinoflagellate Alexandrium catenella, which produces paralytic shellfish toxins (PSTs), was concomitant with the accumulation of PSTs in oyster flesh and the occurrence of C. gigas mortalities. In order to investigate the possible role of toxic algae in this complex disease, we experimentally infected C. gigas oyster juveniles with Vibrio tasmaniensis strain LGP32, a strain associated with oyster summer mortalities, after oysters were exposed to Alexandrium catenella. Exposure of oysters to A. catenella significantly increased the susceptibility of oysters to V. tasmaniensis LGP32. On the contrary, exposure to the non-toxic dinoflagellate Alexandrium tamarense or to the haptophyte Tisochrysis lutea used as a foraging alga did not increase susceptibility to V. tasmaniensis LGP32. This study shows for the first time that A. catenella increases the susceptibility of Crassostrea gigas to pathogenic vibrios. Therefore, in addition to complex environmental factors explaining the mass mortalities of bivalve mollusks, feeding on neurotoxic dinoflagellates should now be considered as an environmental factor that potentially increases the severity of oyster mortality events. Text Crassostrea gigas PubMed Central (PMC) Toxins 8 1 24 |
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Article Abi-Khalil, Celina Lopez-Joven, Carmen Abadie, Eric Savar, Veronique Amzil, Zouher Laabir, Mohamed Rolland, Jean-Luc Exposure to the Paralytic Shellfish Toxin Producer Alexandrium catenella Increases the Susceptibility of the Oyster Crassostrea gigas to Pathogenic Vibrios |
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description |
The multifactorial etiology of massive Crassostrea gigas summer mortalities results from complex interactions between oysters, opportunistic pathogens and environmental factors. In a field survey conducted in 2014 in the Mediterranean Thau Lagoon (France), we evidenced that the development of the toxic dinoflagellate Alexandrium catenella, which produces paralytic shellfish toxins (PSTs), was concomitant with the accumulation of PSTs in oyster flesh and the occurrence of C. gigas mortalities. In order to investigate the possible role of toxic algae in this complex disease, we experimentally infected C. gigas oyster juveniles with Vibrio tasmaniensis strain LGP32, a strain associated with oyster summer mortalities, after oysters were exposed to Alexandrium catenella. Exposure of oysters to A. catenella significantly increased the susceptibility of oysters to V. tasmaniensis LGP32. On the contrary, exposure to the non-toxic dinoflagellate Alexandrium tamarense or to the haptophyte Tisochrysis lutea used as a foraging alga did not increase susceptibility to V. tasmaniensis LGP32. This study shows for the first time that A. catenella increases the susceptibility of Crassostrea gigas to pathogenic vibrios. Therefore, in addition to complex environmental factors explaining the mass mortalities of bivalve mollusks, feeding on neurotoxic dinoflagellates should now be considered as an environmental factor that potentially increases the severity of oyster mortality events. |
format |
Text |
author |
Abi-Khalil, Celina Lopez-Joven, Carmen Abadie, Eric Savar, Veronique Amzil, Zouher Laabir, Mohamed Rolland, Jean-Luc |
author_facet |
Abi-Khalil, Celina Lopez-Joven, Carmen Abadie, Eric Savar, Veronique Amzil, Zouher Laabir, Mohamed Rolland, Jean-Luc |
author_sort |
Abi-Khalil, Celina |
title |
Exposure to the Paralytic Shellfish Toxin Producer Alexandrium catenella Increases the Susceptibility of the Oyster Crassostrea gigas to Pathogenic Vibrios |
title_short |
Exposure to the Paralytic Shellfish Toxin Producer Alexandrium catenella Increases the Susceptibility of the Oyster Crassostrea gigas to Pathogenic Vibrios |
title_full |
Exposure to the Paralytic Shellfish Toxin Producer Alexandrium catenella Increases the Susceptibility of the Oyster Crassostrea gigas to Pathogenic Vibrios |
title_fullStr |
Exposure to the Paralytic Shellfish Toxin Producer Alexandrium catenella Increases the Susceptibility of the Oyster Crassostrea gigas to Pathogenic Vibrios |
title_full_unstemmed |
Exposure to the Paralytic Shellfish Toxin Producer Alexandrium catenella Increases the Susceptibility of the Oyster Crassostrea gigas to Pathogenic Vibrios |
title_sort |
exposure to the paralytic shellfish toxin producer alexandrium catenella increases the susceptibility of the oyster crassostrea gigas to pathogenic vibrios |
publisher |
MDPI |
publishDate |
2016 |
url |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4728546/ http://www.ncbi.nlm.nih.gov/pubmed/26784228 https://doi.org/10.3390/toxins8010024 |
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Crassostrea gigas |
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Crassostrea gigas |
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4728546/ http://www.ncbi.nlm.nih.gov/pubmed/26784228 http://dx.doi.org/10.3390/toxins8010024 |
op_rights |
© 2016 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons by Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/). |
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CC-BY |
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https://doi.org/10.3390/toxins8010024 |
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Toxins |
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24 |
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