Alphacoronaviruses Detected in French Bats Are Phylogeographically Linked to Coronaviruses of European Bats
Bats are a reservoir for a diverse range of viruses, including coronaviruses (CoVs). To determine the presence of CoVs in French bats, fecal samples were collected between July and August of 2014 from four bat species in seven different locations around the city of Bourges in France. We present for...
Published in: | Viruses |
---|---|
Main Authors: | , , , , , |
Format: | Text |
Language: | English |
Published: |
MDPI
2015
|
Subjects: | |
Online Access: | http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4690861/ http://www.ncbi.nlm.nih.gov/pubmed/26633467 https://doi.org/10.3390/v7122937 |
id |
ftpubmed:oai:pubmedcentral.nih.gov:4690861 |
---|---|
record_format |
openpolar |
spelling |
ftpubmed:oai:pubmedcentral.nih.gov:4690861 2023-05-15T17:59:53+02:00 Alphacoronaviruses Detected in French Bats Are Phylogeographically Linked to Coronaviruses of European Bats Goffard, Anne Demanche, Christine Arthur, Laurent Pinçon, Claire Michaux, Johan Dubuisson, Jean 2015-12-02 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4690861/ http://www.ncbi.nlm.nih.gov/pubmed/26633467 https://doi.org/10.3390/v7122937 en eng MDPI http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4690861/ http://www.ncbi.nlm.nih.gov/pubmed/26633467 http://dx.doi.org/10.3390/v7122937 © 2015 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons by Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/). CC-BY Article Text 2015 ftpubmed https://doi.org/10.3390/v7122937 2016-01-10T01:19:18Z Bats are a reservoir for a diverse range of viruses, including coronaviruses (CoVs). To determine the presence of CoVs in French bats, fecal samples were collected between July and August of 2014 from four bat species in seven different locations around the city of Bourges in France. We present for the first time the presence of alpha-CoVs in French Pipistrellus pipistrellus bat species with an estimated prevalence of 4.2%. Based on the analysis of a fragment of the RNA-dependent RNA polymerase (RdRp) gene, phylogenetic analyses show that alpha-CoVs sequences detected in French bats are closely related to other European bat alpha-CoVs. Phylogeographic analyses of RdRp sequences show that several CoVs strains circulate in European bats: (i) old strains detected that have probably diverged a long time ago and are detected in different bat subspecies; (ii) strains detected in Myotis and Pipistrellus bat species that have more recently diverged. Our findings support previous observations describing the complexity of the detected CoVs in bats worldwide. Text Pipistrellus pipistrellus PubMed Central (PMC) Viruses 7 12 6279 6290 |
institution |
Open Polar |
collection |
PubMed Central (PMC) |
op_collection_id |
ftpubmed |
language |
English |
topic |
Article |
spellingShingle |
Article Goffard, Anne Demanche, Christine Arthur, Laurent Pinçon, Claire Michaux, Johan Dubuisson, Jean Alphacoronaviruses Detected in French Bats Are Phylogeographically Linked to Coronaviruses of European Bats |
topic_facet |
Article |
description |
Bats are a reservoir for a diverse range of viruses, including coronaviruses (CoVs). To determine the presence of CoVs in French bats, fecal samples were collected between July and August of 2014 from four bat species in seven different locations around the city of Bourges in France. We present for the first time the presence of alpha-CoVs in French Pipistrellus pipistrellus bat species with an estimated prevalence of 4.2%. Based on the analysis of a fragment of the RNA-dependent RNA polymerase (RdRp) gene, phylogenetic analyses show that alpha-CoVs sequences detected in French bats are closely related to other European bat alpha-CoVs. Phylogeographic analyses of RdRp sequences show that several CoVs strains circulate in European bats: (i) old strains detected that have probably diverged a long time ago and are detected in different bat subspecies; (ii) strains detected in Myotis and Pipistrellus bat species that have more recently diverged. Our findings support previous observations describing the complexity of the detected CoVs in bats worldwide. |
format |
Text |
author |
Goffard, Anne Demanche, Christine Arthur, Laurent Pinçon, Claire Michaux, Johan Dubuisson, Jean |
author_facet |
Goffard, Anne Demanche, Christine Arthur, Laurent Pinçon, Claire Michaux, Johan Dubuisson, Jean |
author_sort |
Goffard, Anne |
title |
Alphacoronaviruses Detected in French Bats Are Phylogeographically Linked to Coronaviruses of European Bats |
title_short |
Alphacoronaviruses Detected in French Bats Are Phylogeographically Linked to Coronaviruses of European Bats |
title_full |
Alphacoronaviruses Detected in French Bats Are Phylogeographically Linked to Coronaviruses of European Bats |
title_fullStr |
Alphacoronaviruses Detected in French Bats Are Phylogeographically Linked to Coronaviruses of European Bats |
title_full_unstemmed |
Alphacoronaviruses Detected in French Bats Are Phylogeographically Linked to Coronaviruses of European Bats |
title_sort |
alphacoronaviruses detected in french bats are phylogeographically linked to coronaviruses of european bats |
publisher |
MDPI |
publishDate |
2015 |
url |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4690861/ http://www.ncbi.nlm.nih.gov/pubmed/26633467 https://doi.org/10.3390/v7122937 |
genre |
Pipistrellus pipistrellus |
genre_facet |
Pipistrellus pipistrellus |
op_relation |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4690861/ http://www.ncbi.nlm.nih.gov/pubmed/26633467 http://dx.doi.org/10.3390/v7122937 |
op_rights |
© 2015 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons by Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/). |
op_rightsnorm |
CC-BY |
op_doi |
https://doi.org/10.3390/v7122937 |
container_title |
Viruses |
container_volume |
7 |
container_issue |
12 |
container_start_page |
6279 |
op_container_end_page |
6290 |
_version_ |
1766168782350319616 |