Metabolic programming mediated by an essential fatty acid alters body composition and survival skills of a marine fish
Metabolic programming occurs when variations in nutrition during a specific developmental window result in long-term metabolic effects. It has been studied almost exclusively in humans and other mammals but never in an ecological context. Here, we report metabolic programming and its functional cons...
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ftpubmed:oai:pubmedcentral.nih.gov:4685801 2023-05-15T18:06:04+02:00 Metabolic programming mediated by an essential fatty acid alters body composition and survival skills of a marine fish Fuiman, Lee A. Perez, Kestrel O. 2015-11-22 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4685801/ http://www.ncbi.nlm.nih.gov/pubmed/26582018 https://doi.org/10.1098/rspb.2015.1414 en eng The Royal Society http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4685801/ http://www.ncbi.nlm.nih.gov/pubmed/26582018 http://dx.doi.org/10.1098/rspb.2015.1414 © 2015 The Author(s) http://royalsocietypublishing.org/licence Published by the Royal Society. All rights reserved. Research Articles Text 2015 ftpubmed https://doi.org/10.1098/rspb.2015.1414 2016-11-27T01:02:06Z Metabolic programming occurs when variations in nutrition during a specific developmental window result in long-term metabolic effects. It has been studied almost exclusively in humans and other mammals but never in an ecological context. Here, we report metabolic programming and its functional consequences in a marine fish, red drum. We demonstrate that maternal provisioning of eggs with an essential fatty acid, docosahexaenoic acid (DHA), varies with DHA content of the maternal diet. When offspring are reared on a DHA-replete diet, whole-body DHA content of offspring depends upon the amount of DHA that was in the egg. We further demonstrate that whole-body DHA content is correlated with traits related to offspring fitness (escape responses, routine swimming, growth, and survival). DHA content of red drum eggs produced in nature is in the range where the effects of metabolic programming are most pronounced. Our findings indicate that during a brief developmental window, DHA plays a role in establishing the metabolic capacity for its own uptake or storage, with protracted and possibly permanent effects on ecologically important survival skills of individuals and important implications for dynamics of populations and food webs. Text Red drum PubMed Central (PMC) Proceedings of the Royal Society B: Biological Sciences 282 1819 20151414 |
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Research Articles Fuiman, Lee A. Perez, Kestrel O. Metabolic programming mediated by an essential fatty acid alters body composition and survival skills of a marine fish |
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Research Articles |
description |
Metabolic programming occurs when variations in nutrition during a specific developmental window result in long-term metabolic effects. It has been studied almost exclusively in humans and other mammals but never in an ecological context. Here, we report metabolic programming and its functional consequences in a marine fish, red drum. We demonstrate that maternal provisioning of eggs with an essential fatty acid, docosahexaenoic acid (DHA), varies with DHA content of the maternal diet. When offspring are reared on a DHA-replete diet, whole-body DHA content of offspring depends upon the amount of DHA that was in the egg. We further demonstrate that whole-body DHA content is correlated with traits related to offspring fitness (escape responses, routine swimming, growth, and survival). DHA content of red drum eggs produced in nature is in the range where the effects of metabolic programming are most pronounced. Our findings indicate that during a brief developmental window, DHA plays a role in establishing the metabolic capacity for its own uptake or storage, with protracted and possibly permanent effects on ecologically important survival skills of individuals and important implications for dynamics of populations and food webs. |
format |
Text |
author |
Fuiman, Lee A. Perez, Kestrel O. |
author_facet |
Fuiman, Lee A. Perez, Kestrel O. |
author_sort |
Fuiman, Lee A. |
title |
Metabolic programming mediated by an essential fatty acid alters body composition and survival skills of a marine fish |
title_short |
Metabolic programming mediated by an essential fatty acid alters body composition and survival skills of a marine fish |
title_full |
Metabolic programming mediated by an essential fatty acid alters body composition and survival skills of a marine fish |
title_fullStr |
Metabolic programming mediated by an essential fatty acid alters body composition and survival skills of a marine fish |
title_full_unstemmed |
Metabolic programming mediated by an essential fatty acid alters body composition and survival skills of a marine fish |
title_sort |
metabolic programming mediated by an essential fatty acid alters body composition and survival skills of a marine fish |
publisher |
The Royal Society |
publishDate |
2015 |
url |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4685801/ http://www.ncbi.nlm.nih.gov/pubmed/26582018 https://doi.org/10.1098/rspb.2015.1414 |
genre |
Red drum |
genre_facet |
Red drum |
op_relation |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4685801/ http://www.ncbi.nlm.nih.gov/pubmed/26582018 http://dx.doi.org/10.1098/rspb.2015.1414 |
op_rights |
© 2015 The Author(s) http://royalsocietypublishing.org/licence Published by the Royal Society. All rights reserved. |
op_doi |
https://doi.org/10.1098/rspb.2015.1414 |
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Proceedings of the Royal Society B: Biological Sciences |
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282 |
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1819 |
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20151414 |
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1766177638192250880 |