Demonstration of the Coexistence of Duplicated LH Receptors in Teleosts, and Their Origin in Ancestral Actinopterygians

• Published in: PLOS ONE
• Main Authors: Maugars, Gersende, Dufour, Sylvie
• Format: Text
• Language: English
• Published: Public Library of Science 2015
• Subjects: Research Article; Gar’; European eel
• Online Access: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4536197/; http://www.ncbi.nlm.nih.gov/pubmed/26271038; https://doi.org/10.1371/journal.pone.0135184

Pituitary gonadotropins, FSH and LH, control gonad activity in vertebrates, via binding to their respective receptors, FSHR and LHR, members of GPCR superfamily. Until recently, it was accepted that gnathostomes possess a single FSHR and a single LHR, encoded by fshr and lhcgr genes. We reinvestigat...