Global transcriptional analysis of short-term hepatic stress responses in Atlantic salmon (Salmo salar) exposed to depleted uranium
Potential environmental hazards of radionuclides are often studied at the individual level. Sufficient toxicogenomics data at the molecular/cellular level for understanding the effects and modes of toxic action (MoAs) of radionuclide is still lacking. The current article introduces transcriptomic da...
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ftpubmed:oai:pubmedcentral.nih.gov:4535871 2023-05-15T15:31:08+02:00 Global transcriptional analysis of short-term hepatic stress responses in Atlantic salmon (Salmo salar) exposed to depleted uranium Song, You Salbu, Brit Teien, Hans-Christian Heier, Lene Sørlie Rosseland, Bjørn Olav Høgåsen, Tore Tollefsen, Knut Erik 2014-10-07 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4535871/ http://www.ncbi.nlm.nih.gov/pubmed/26484125 https://doi.org/10.1016/j.gdata.2014.10.003 en eng Elsevier http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4535871/ http://www.ncbi.nlm.nih.gov/pubmed/26484125 http://dx.doi.org/10.1016/j.gdata.2014.10.003 © 2014 The Authors http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/3.0/). CC-BY-NC-ND Data in Brief Text 2014 ftpubmed https://doi.org/10.1016/j.gdata.2014.10.003 2015-10-25T00:11:07Z Potential environmental hazards of radionuclides are often studied at the individual level. Sufficient toxicogenomics data at the molecular/cellular level for understanding the effects and modes of toxic action (MoAs) of radionuclide is still lacking. The current article introduces transcriptomic data generated from a recent ecotoxicological study, with the aims to characterize the MoAs of a metallic radionuclide, deplete uranium (DU) in an ecologically and commercially important fish species, Atlantic salmon (Salmo salar). Salmon were exposed to three concentrations (0.25, 0.5 and 1.0 mg/L) of DU for 48 h. Short-term global transcriptional responses were studied using Agilent custom-designed high density 60,000-feature (60 k) salmonid oligonucleotide microarrays (oligoarray). The microarray datasets deposited at Gene Expression Omnibus (GEO ID: GSE58824) were associated with a recently published study by Song et al. (2014) in BMC Genomics. The authors describe the experimental data herein to build a platform for better understanding the toxic mechanisms and ecological hazard of radionuclides such as DU in fish. Text Atlantic salmon Salmo salar PubMed Central (PMC) Genomics Data 2 340 341 |
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English |
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Data in Brief |
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Data in Brief Song, You Salbu, Brit Teien, Hans-Christian Heier, Lene Sørlie Rosseland, Bjørn Olav Høgåsen, Tore Tollefsen, Knut Erik Global transcriptional analysis of short-term hepatic stress responses in Atlantic salmon (Salmo salar) exposed to depleted uranium |
topic_facet |
Data in Brief |
description |
Potential environmental hazards of radionuclides are often studied at the individual level. Sufficient toxicogenomics data at the molecular/cellular level for understanding the effects and modes of toxic action (MoAs) of radionuclide is still lacking. The current article introduces transcriptomic data generated from a recent ecotoxicological study, with the aims to characterize the MoAs of a metallic radionuclide, deplete uranium (DU) in an ecologically and commercially important fish species, Atlantic salmon (Salmo salar). Salmon were exposed to three concentrations (0.25, 0.5 and 1.0 mg/L) of DU for 48 h. Short-term global transcriptional responses were studied using Agilent custom-designed high density 60,000-feature (60 k) salmonid oligonucleotide microarrays (oligoarray). The microarray datasets deposited at Gene Expression Omnibus (GEO ID: GSE58824) were associated with a recently published study by Song et al. (2014) in BMC Genomics. The authors describe the experimental data herein to build a platform for better understanding the toxic mechanisms and ecological hazard of radionuclides such as DU in fish. |
format |
Text |
author |
Song, You Salbu, Brit Teien, Hans-Christian Heier, Lene Sørlie Rosseland, Bjørn Olav Høgåsen, Tore Tollefsen, Knut Erik |
author_facet |
Song, You Salbu, Brit Teien, Hans-Christian Heier, Lene Sørlie Rosseland, Bjørn Olav Høgåsen, Tore Tollefsen, Knut Erik |
author_sort |
Song, You |
title |
Global transcriptional analysis of short-term hepatic stress responses in Atlantic salmon (Salmo salar) exposed to depleted uranium |
title_short |
Global transcriptional analysis of short-term hepatic stress responses in Atlantic salmon (Salmo salar) exposed to depleted uranium |
title_full |
Global transcriptional analysis of short-term hepatic stress responses in Atlantic salmon (Salmo salar) exposed to depleted uranium |
title_fullStr |
Global transcriptional analysis of short-term hepatic stress responses in Atlantic salmon (Salmo salar) exposed to depleted uranium |
title_full_unstemmed |
Global transcriptional analysis of short-term hepatic stress responses in Atlantic salmon (Salmo salar) exposed to depleted uranium |
title_sort |
global transcriptional analysis of short-term hepatic stress responses in atlantic salmon (salmo salar) exposed to depleted uranium |
publisher |
Elsevier |
publishDate |
2014 |
url |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4535871/ http://www.ncbi.nlm.nih.gov/pubmed/26484125 https://doi.org/10.1016/j.gdata.2014.10.003 |
genre |
Atlantic salmon Salmo salar |
genre_facet |
Atlantic salmon Salmo salar |
op_relation |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4535871/ http://www.ncbi.nlm.nih.gov/pubmed/26484125 http://dx.doi.org/10.1016/j.gdata.2014.10.003 |
op_rights |
© 2014 The Authors http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/3.0/). |
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CC-BY-NC-ND |
op_doi |
https://doi.org/10.1016/j.gdata.2014.10.003 |
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Genomics Data |
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2 |
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340 |
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341 |
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1766361632657637376 |