Autophagy plays an important role in protecting Pacific oysters from OsHV-1 and Vibrio aestuarianus infections
Recent mass mortality outbreaks around the world in Pacific oysters, Crassostrea gigas, have seriously affected the aquaculture economy. Although the causes for these mortality outbreaks appear complex, infectious agents are involved. Two pathogens are associated with mass mortality outbreaks, the v...
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ftpubmed:oai:pubmedcentral.nih.gov:4502751 2023-05-15T15:58:23+02:00 Autophagy plays an important role in protecting Pacific oysters from OsHV-1 and Vibrio aestuarianus infections Moreau, Pierrick Moreau, Kevin Segarra, Amélie Tourbiez, Delphine Travers, Marie-Agnès Rubinsztein, David C Renault, Tristan 2015-02-25 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4502751/ http://www.ncbi.nlm.nih.gov/pubmed/25714877 https://doi.org/10.1080/15548627.2015.1017188 en eng Taylor & Francis http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4502751/ http://www.ncbi.nlm.nih.gov/pubmed/25714877 http://dx.doi.org/10.1080/15548627.2015.1017188 © 2015 The Author(s). Published with license by Taylor & Francis Group, LLC http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. The moral rights of the named author(s) have been asserted. CC-BY-NC Basic Research Paper Text 2015 ftpubmed https://doi.org/10.1080/15548627.2015.1017188 2016-02-07T01:15:45Z Recent mass mortality outbreaks around the world in Pacific oysters, Crassostrea gigas, have seriously affected the aquaculture economy. Although the causes for these mortality outbreaks appear complex, infectious agents are involved. Two pathogens are associated with mass mortality outbreaks, the virus ostreid herpesvirus 1 (OsHV-1) and the bacterium Vibrio aestuarianus. Here we describe the interactions between these 2 pathogens and autophagy, a conserved intracellular pathway playing a key role in innate immunity. We show for the first time that autophagy pathway is present and functional in Pacific oysters and plays an important role to protect animals from infections. This study contributes to better understand the innate immune system of Pacific oysters. Text Crassostrea gigas PubMed Central (PMC) Pacific Autophagy 11 3 516 526 |
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Basic Research Paper |
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Basic Research Paper Moreau, Pierrick Moreau, Kevin Segarra, Amélie Tourbiez, Delphine Travers, Marie-Agnès Rubinsztein, David C Renault, Tristan Autophagy plays an important role in protecting Pacific oysters from OsHV-1 and Vibrio aestuarianus infections |
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Basic Research Paper |
description |
Recent mass mortality outbreaks around the world in Pacific oysters, Crassostrea gigas, have seriously affected the aquaculture economy. Although the causes for these mortality outbreaks appear complex, infectious agents are involved. Two pathogens are associated with mass mortality outbreaks, the virus ostreid herpesvirus 1 (OsHV-1) and the bacterium Vibrio aestuarianus. Here we describe the interactions between these 2 pathogens and autophagy, a conserved intracellular pathway playing a key role in innate immunity. We show for the first time that autophagy pathway is present and functional in Pacific oysters and plays an important role to protect animals from infections. This study contributes to better understand the innate immune system of Pacific oysters. |
format |
Text |
author |
Moreau, Pierrick Moreau, Kevin Segarra, Amélie Tourbiez, Delphine Travers, Marie-Agnès Rubinsztein, David C Renault, Tristan |
author_facet |
Moreau, Pierrick Moreau, Kevin Segarra, Amélie Tourbiez, Delphine Travers, Marie-Agnès Rubinsztein, David C Renault, Tristan |
author_sort |
Moreau, Pierrick |
title |
Autophagy plays an important role in protecting Pacific oysters from OsHV-1 and Vibrio aestuarianus infections |
title_short |
Autophagy plays an important role in protecting Pacific oysters from OsHV-1 and Vibrio aestuarianus infections |
title_full |
Autophagy plays an important role in protecting Pacific oysters from OsHV-1 and Vibrio aestuarianus infections |
title_fullStr |
Autophagy plays an important role in protecting Pacific oysters from OsHV-1 and Vibrio aestuarianus infections |
title_full_unstemmed |
Autophagy plays an important role in protecting Pacific oysters from OsHV-1 and Vibrio aestuarianus infections |
title_sort |
autophagy plays an important role in protecting pacific oysters from oshv-1 and vibrio aestuarianus infections |
publisher |
Taylor & Francis |
publishDate |
2015 |
url |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4502751/ http://www.ncbi.nlm.nih.gov/pubmed/25714877 https://doi.org/10.1080/15548627.2015.1017188 |
geographic |
Pacific |
geographic_facet |
Pacific |
genre |
Crassostrea gigas |
genre_facet |
Crassostrea gigas |
op_relation |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4502751/ http://www.ncbi.nlm.nih.gov/pubmed/25714877 http://dx.doi.org/10.1080/15548627.2015.1017188 |
op_rights |
© 2015 The Author(s). Published with license by Taylor & Francis Group, LLC http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. The moral rights of the named author(s) have been asserted. |
op_rightsnorm |
CC-BY-NC |
op_doi |
https://doi.org/10.1080/15548627.2015.1017188 |
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Autophagy |
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11 |
container_issue |
3 |
container_start_page |
516 |
op_container_end_page |
526 |
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1766394124546605056 |