No Genome-Wide Protein Sequence Convergence for Echolocation
Toothed whales and two groups of bats independently acquired echolocation, the ability to locate and identify objects by reflected sound. Echolocation requires physiologically complex and coordinated vocal, auditory, and neural functions, but the molecular basis of the capacity for echolocation is n...
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ftpubmed:oai:pubmedcentral.nih.gov:4408410 2023-05-15T18:33:30+02:00 No Genome-Wide Protein Sequence Convergence for Echolocation Zou, Zhengting Zhang, Jianzhi 2015-05 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4408410/ http://www.ncbi.nlm.nih.gov/pubmed/25631925 https://doi.org/10.1093/molbev/msv014 en eng Oxford University Press http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4408410/ http://www.ncbi.nlm.nih.gov/pubmed/25631925 http://dx.doi.org/10.1093/molbev/msv014 © The Author 2015. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com Discoveries Text 2015 ftpubmed https://doi.org/10.1093/molbev/msv014 2016-05-08T00:04:46Z Toothed whales and two groups of bats independently acquired echolocation, the ability to locate and identify objects by reflected sound. Echolocation requires physiologically complex and coordinated vocal, auditory, and neural functions, but the molecular basis of the capacity for echolocation is not well understood. A recent study suggested that convergent amino acid substitutions widespread in the proteins of echolocators underlay the convergent origins of mammalian echolocation. Here, we show that genomic signatures of molecular convergence between echolocating lineages are generally no stronger than those between echolocating and comparable nonecholocating lineages. The same is true for the group of 29 hearing-related proteins claimed to be enriched with molecular convergence. Reexamining the previous selection test reveals several flaws and invalidates the asserted evidence for adaptive convergence. Together, these findings indicate that the reported genomic signatures of convergence largely reflect the background level of sequence convergence unrelated to the origins of echolocation. Text toothed whales PubMed Central (PMC) Molecular Biology and Evolution 32 5 1237 1241 |
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Discoveries Zou, Zhengting Zhang, Jianzhi No Genome-Wide Protein Sequence Convergence for Echolocation |
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Discoveries |
description |
Toothed whales and two groups of bats independently acquired echolocation, the ability to locate and identify objects by reflected sound. Echolocation requires physiologically complex and coordinated vocal, auditory, and neural functions, but the molecular basis of the capacity for echolocation is not well understood. A recent study suggested that convergent amino acid substitutions widespread in the proteins of echolocators underlay the convergent origins of mammalian echolocation. Here, we show that genomic signatures of molecular convergence between echolocating lineages are generally no stronger than those between echolocating and comparable nonecholocating lineages. The same is true for the group of 29 hearing-related proteins claimed to be enriched with molecular convergence. Reexamining the previous selection test reveals several flaws and invalidates the asserted evidence for adaptive convergence. Together, these findings indicate that the reported genomic signatures of convergence largely reflect the background level of sequence convergence unrelated to the origins of echolocation. |
format |
Text |
author |
Zou, Zhengting Zhang, Jianzhi |
author_facet |
Zou, Zhengting Zhang, Jianzhi |
author_sort |
Zou, Zhengting |
title |
No Genome-Wide Protein Sequence Convergence for Echolocation |
title_short |
No Genome-Wide Protein Sequence Convergence for Echolocation |
title_full |
No Genome-Wide Protein Sequence Convergence for Echolocation |
title_fullStr |
No Genome-Wide Protein Sequence Convergence for Echolocation |
title_full_unstemmed |
No Genome-Wide Protein Sequence Convergence for Echolocation |
title_sort |
no genome-wide protein sequence convergence for echolocation |
publisher |
Oxford University Press |
publishDate |
2015 |
url |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4408410/ http://www.ncbi.nlm.nih.gov/pubmed/25631925 https://doi.org/10.1093/molbev/msv014 |
genre |
toothed whales |
genre_facet |
toothed whales |
op_relation |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4408410/ http://www.ncbi.nlm.nih.gov/pubmed/25631925 http://dx.doi.org/10.1093/molbev/msv014 |
op_rights |
© The Author 2015. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com |
op_doi |
https://doi.org/10.1093/molbev/msv014 |
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Molecular Biology and Evolution |
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32 |
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5 |
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1237 |
op_container_end_page |
1241 |
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1766218116196466688 |