Peopling of the North Circumpolar Region – Insights from Y Chromosome STR and SNP Typing of Greenlanders
The human population in Greenland is characterized by migration events of Paleo- and Neo-Eskimos, as well as admixture with Europeans. In this study, the Y-chromosomal variation in male Greenlanders was investigated in detail by typing 73 Y-chromosomal single nucleotide polymorphisms (Y-SNPs) and 17...
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ftpubmed:oai:pubmedcentral.nih.gov:4312058 2023-05-15T16:02:16+02:00 Peopling of the North Circumpolar Region – Insights from Y Chromosome STR and SNP Typing of Greenlanders Olofsson, Jill Katharina Pereira, Vania Børsting, Claus Morling, Niels 2015-01-30 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4312058 http://www.ncbi.nlm.nih.gov/pubmed/25635810 https://doi.org/10.1371/journal.pone.0116573 en eng Public Library of Science http://www.ncbi.nlm.nih.gov/pmc/articles/PMC http://www.ncbi.nlm.nih.gov/pubmed/25635810 http://dx.doi.org/10.1371/journal.pone.0116573 http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited CC-BY Research Article Text 2015 ftpubmed https://doi.org/10.1371/journal.pone.0116573 2015-02-15T00:56:41Z The human population in Greenland is characterized by migration events of Paleo- and Neo-Eskimos, as well as admixture with Europeans. In this study, the Y-chromosomal variation in male Greenlanders was investigated in detail by typing 73 Y-chromosomal single nucleotide polymorphisms (Y-SNPs) and 17 Y-chromosomal short tandem repeats (Y-STRs). Approximately 40% of the analyzed Greenlandic Y chromosomes were of European origin (I-M170, R1a-M513 and R1b-M343). Y chromosomes of European origin were mainly found in individuals from the west and south coasts of Greenland, which is in agreement with the historic records of the geographic placements of European settlements in Greenland. Two Inuit Y-chromosomal lineages, Q-M3 (xM19, M194, L663, SA01 and L766) and Q-NWT01 (xM265) were found in 23% and 31% of the male Greenlanders, respectively. The time to the most recent common ancestor (TMRCA) of the Q-M3 lineage of the Greenlanders was estimated to be between 4,400 and 10,900 years ago (y. a.) using two different methods. This is in agreement with the theory that the North Circumpolar Region was populated via a second expansion of humans in the North American continent. The TMRCA of the Q-NWT01 (xM265) lineage in Greenland was estimated to be between 7,000 and 14,300 y. a. using two different methods, which is older than the previously reported TMRCA of this lineage in other Inuit populations. Our results indicate that Inuit individuals carrying the Q-NWT01 (xM265) lineage may have their origin in the northeastern parts of North America and could be descendants of the Dorset culture. This in turn points to the possibility that the current Inuit population in Greenland is comprised of individuals of both Thule and Dorset descent. Text Dorset culture eskimo* Greenland greenlander* greenlandic inuit Thule PubMed Central (PMC) Greenland The ''Y'' ENVELOPE(-112.453,-112.453,57.591,57.591) PLOS ONE 10 1 e0116573 |
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Research Article |
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Research Article Olofsson, Jill Katharina Pereira, Vania Børsting, Claus Morling, Niels Peopling of the North Circumpolar Region – Insights from Y Chromosome STR and SNP Typing of Greenlanders |
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Research Article |
description |
The human population in Greenland is characterized by migration events of Paleo- and Neo-Eskimos, as well as admixture with Europeans. In this study, the Y-chromosomal variation in male Greenlanders was investigated in detail by typing 73 Y-chromosomal single nucleotide polymorphisms (Y-SNPs) and 17 Y-chromosomal short tandem repeats (Y-STRs). Approximately 40% of the analyzed Greenlandic Y chromosomes were of European origin (I-M170, R1a-M513 and R1b-M343). Y chromosomes of European origin were mainly found in individuals from the west and south coasts of Greenland, which is in agreement with the historic records of the geographic placements of European settlements in Greenland. Two Inuit Y-chromosomal lineages, Q-M3 (xM19, M194, L663, SA01 and L766) and Q-NWT01 (xM265) were found in 23% and 31% of the male Greenlanders, respectively. The time to the most recent common ancestor (TMRCA) of the Q-M3 lineage of the Greenlanders was estimated to be between 4,400 and 10,900 years ago (y. a.) using two different methods. This is in agreement with the theory that the North Circumpolar Region was populated via a second expansion of humans in the North American continent. The TMRCA of the Q-NWT01 (xM265) lineage in Greenland was estimated to be between 7,000 and 14,300 y. a. using two different methods, which is older than the previously reported TMRCA of this lineage in other Inuit populations. Our results indicate that Inuit individuals carrying the Q-NWT01 (xM265) lineage may have their origin in the northeastern parts of North America and could be descendants of the Dorset culture. This in turn points to the possibility that the current Inuit population in Greenland is comprised of individuals of both Thule and Dorset descent. |
format |
Text |
author |
Olofsson, Jill Katharina Pereira, Vania Børsting, Claus Morling, Niels |
author_facet |
Olofsson, Jill Katharina Pereira, Vania Børsting, Claus Morling, Niels |
author_sort |
Olofsson, Jill Katharina |
title |
Peopling of the North Circumpolar Region – Insights from Y Chromosome STR and SNP Typing of Greenlanders |
title_short |
Peopling of the North Circumpolar Region – Insights from Y Chromosome STR and SNP Typing of Greenlanders |
title_full |
Peopling of the North Circumpolar Region – Insights from Y Chromosome STR and SNP Typing of Greenlanders |
title_fullStr |
Peopling of the North Circumpolar Region – Insights from Y Chromosome STR and SNP Typing of Greenlanders |
title_full_unstemmed |
Peopling of the North Circumpolar Region – Insights from Y Chromosome STR and SNP Typing of Greenlanders |
title_sort |
peopling of the north circumpolar region – insights from y chromosome str and snp typing of greenlanders |
publisher |
Public Library of Science |
publishDate |
2015 |
url |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4312058 http://www.ncbi.nlm.nih.gov/pubmed/25635810 https://doi.org/10.1371/journal.pone.0116573 |
long_lat |
ENVELOPE(-112.453,-112.453,57.591,57.591) |
geographic |
Greenland The ''Y'' |
geographic_facet |
Greenland The ''Y'' |
genre |
Dorset culture eskimo* Greenland greenlander* greenlandic inuit Thule |
genre_facet |
Dorset culture eskimo* Greenland greenlander* greenlandic inuit Thule |
op_relation |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC http://www.ncbi.nlm.nih.gov/pubmed/25635810 http://dx.doi.org/10.1371/journal.pone.0116573 |
op_rights |
http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited |
op_rightsnorm |
CC-BY |
op_doi |
https://doi.org/10.1371/journal.pone.0116573 |
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PLOS ONE |
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10 |
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1 |
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e0116573 |
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