Hormonal and Dietary Characteristics in Obese Human Subjects with and without Food Addiction
The concept of food addiction (FA) is a potentially important contributing factor to the development of obesity in the general population; however, little is known about the hormonal and dietary differences between obesity with and without FA. Therefore, the aim of our study was to explore potential...
Published in: | Nutrients |
---|---|
Main Authors: | , |
Format: | Text |
Language: | English |
Published: |
MDPI
2014
|
Subjects: | |
Online Access: | http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4303835 http://www.ncbi.nlm.nih.gov/pubmed/25558907 https://doi.org/10.3390/nu7010223 |
id |
ftpubmed:oai:pubmedcentral.nih.gov:4303835 |
---|---|
record_format |
openpolar |
spelling |
ftpubmed:oai:pubmedcentral.nih.gov:4303835 2023-05-15T17:22:44+02:00 Hormonal and Dietary Characteristics in Obese Human Subjects with and without Food Addiction Pedram, Pardis Sun, Guang 2014-12-31 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4303835 http://www.ncbi.nlm.nih.gov/pubmed/25558907 https://doi.org/10.3390/nu7010223 en eng MDPI http://www.ncbi.nlm.nih.gov/pmc/articles/PMC http://www.ncbi.nlm.nih.gov/pubmed/25558907 http://dx.doi.org/10.3390/nu7010223 © 2014 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/4.0/). CC-BY Article Text 2014 ftpubmed https://doi.org/10.3390/nu7010223 2015-02-08T01:11:00Z The concept of food addiction (FA) is a potentially important contributing factor to the development of obesity in the general population; however, little is known about the hormonal and dietary differences between obesity with and without FA. Therefore, the aim of our study was to explore potential biomarkers, including various hormones and neuropeptides, which regulate appetite and metabolism, and dietary components that could potentially differentiate obesity with and without FA. Of the 737 adults recruited from the general Newfoundland population, 58 food-addicted and non-food-addicted overweight/obese individuals (FAO, NFO) matched for age, sex, BMI and physical activity were selected. A total of 34 neuropeptides, gut hormones, pituitary polypeptide hormones and adipokines were measured in fasting serum. We found that the FAO group had lower levels of TSH, TNF-α and amylin, but higher levels of prolactin, as compared to NFO group. The total calorie intake (per kg body weight), the dietary intake of fat (per g/kg body weight, per BMI and per percentage of trunk fat) and the percent calorie intake from fat and carbohydrates (g/kg) was higher in the FAO group compared to the NFO group. The FAO subjects consumed more sugar, minerals (including sodium, potassium, calcium and selenium), fat and its components (such as saturated, monounsaturated and trans fat), omega 3 and 6, vitamin D and gamma-tocopherol compared to the NFO group. To our knowledge, this is the first study indicating possible differences in hormonal levels and micro-nutrient intakes between obese individuals classified with and without food addiction. The findings provide insights into the mechanisms by which FA could contribute to obesity. Text Newfoundland PubMed Central (PMC) Nutrients 7 1 223 238 |
institution |
Open Polar |
collection |
PubMed Central (PMC) |
op_collection_id |
ftpubmed |
language |
English |
topic |
Article |
spellingShingle |
Article Pedram, Pardis Sun, Guang Hormonal and Dietary Characteristics in Obese Human Subjects with and without Food Addiction |
topic_facet |
Article |
description |
The concept of food addiction (FA) is a potentially important contributing factor to the development of obesity in the general population; however, little is known about the hormonal and dietary differences between obesity with and without FA. Therefore, the aim of our study was to explore potential biomarkers, including various hormones and neuropeptides, which regulate appetite and metabolism, and dietary components that could potentially differentiate obesity with and without FA. Of the 737 adults recruited from the general Newfoundland population, 58 food-addicted and non-food-addicted overweight/obese individuals (FAO, NFO) matched for age, sex, BMI and physical activity were selected. A total of 34 neuropeptides, gut hormones, pituitary polypeptide hormones and adipokines were measured in fasting serum. We found that the FAO group had lower levels of TSH, TNF-α and amylin, but higher levels of prolactin, as compared to NFO group. The total calorie intake (per kg body weight), the dietary intake of fat (per g/kg body weight, per BMI and per percentage of trunk fat) and the percent calorie intake from fat and carbohydrates (g/kg) was higher in the FAO group compared to the NFO group. The FAO subjects consumed more sugar, minerals (including sodium, potassium, calcium and selenium), fat and its components (such as saturated, monounsaturated and trans fat), omega 3 and 6, vitamin D and gamma-tocopherol compared to the NFO group. To our knowledge, this is the first study indicating possible differences in hormonal levels and micro-nutrient intakes between obese individuals classified with and without food addiction. The findings provide insights into the mechanisms by which FA could contribute to obesity. |
format |
Text |
author |
Pedram, Pardis Sun, Guang |
author_facet |
Pedram, Pardis Sun, Guang |
author_sort |
Pedram, Pardis |
title |
Hormonal and Dietary Characteristics in Obese Human Subjects with and without Food Addiction |
title_short |
Hormonal and Dietary Characteristics in Obese Human Subjects with and without Food Addiction |
title_full |
Hormonal and Dietary Characteristics in Obese Human Subjects with and without Food Addiction |
title_fullStr |
Hormonal and Dietary Characteristics in Obese Human Subjects with and without Food Addiction |
title_full_unstemmed |
Hormonal and Dietary Characteristics in Obese Human Subjects with and without Food Addiction |
title_sort |
hormonal and dietary characteristics in obese human subjects with and without food addiction |
publisher |
MDPI |
publishDate |
2014 |
url |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4303835 http://www.ncbi.nlm.nih.gov/pubmed/25558907 https://doi.org/10.3390/nu7010223 |
genre |
Newfoundland |
genre_facet |
Newfoundland |
op_relation |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC http://www.ncbi.nlm.nih.gov/pubmed/25558907 http://dx.doi.org/10.3390/nu7010223 |
op_rights |
© 2014 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/4.0/). |
op_rightsnorm |
CC-BY |
op_doi |
https://doi.org/10.3390/nu7010223 |
container_title |
Nutrients |
container_volume |
7 |
container_issue |
1 |
container_start_page |
223 |
op_container_end_page |
238 |
_version_ |
1766109575971340288 |