Drug use during early pregnancy: Cross-sectional analysis from the Childbirth and Health Study in Primary Care in Iceland
Objective. To analyse drug use in early pregnancy with special focus on socio-demographic factors associated with psychotropic and analgesic drug use. Design. Cross-sectional study. Setting and subjects. A total of 1765 women were invited via their local health care centres, and 1111 participated at...
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ftpubmed:oai:pubmedcentral.nih.gov:4206559 2023-05-15T16:51:39+02:00 Drug use during early pregnancy: Cross-sectional analysis from the Childbirth and Health Study in Primary Care in Iceland Axelsdottir, Thury O. Sigurdsson, Emil L. Gudmundsdottir, Anna M. Kristjansdottir, Hildur Sigurdsson, Johann A. 2014-09 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4206559 http://www.ncbi.nlm.nih.gov/pubmed/25299613 https://doi.org/10.3109/02813432.2014.965884 en eng Informa Healthcare http://www.ncbi.nlm.nih.gov/pmc/articles/PMC http://www.ncbi.nlm.nih.gov/pubmed/25299613 http://dx.doi.org/10.3109/02813432.2014.965884 © 2014 The Author(s) http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) CC-BY-NC Original Article Text 2014 ftpubmed https://doi.org/10.3109/02813432.2014.965884 2014-11-09T01:10:37Z Objective. To analyse drug use in early pregnancy with special focus on socio-demographic factors associated with psychotropic and analgesic drug use. Design. Cross-sectional study. Setting and subjects. A total of 1765 women were invited via their local health care centres, and 1111 participated at 11–16 weeks of pregnancy by filling out a postal questionnaire concerning socio-demographic and obstetric background, stressful life events, and drug use. Main outcome measures. Drug use prior to and early on in pregnancy, socio-demographic factors, smoking, and adverse life events were investigated. Drug categories screened for were psychotropics (collective term for antidepressants, relaxants, and sleep medication), analgesics, hormones, nicotine, vitamins/minerals, and homeopathic medicine. Results. Drug use from the aforementioned drug categories, excluding vitamins/minerals and homeopathic medicine, was reduced by 18% during early pregnancy, compared with six months prior to conception (49% vs. 60%). Psychotropic drug use during early pregnancy was associated with elementary maternal education (p < 0.5), being unemployed (p < 0.001), being single/divorced/separated (p < 0.01), smoking prior to or during pregnancy (p < 0.01), forced to change job/move house (p < 0.001), and psychotropic drug use six months prior to pregnancy (p < 0.001). No items on the stressful life events scale were associated with increased analgesic use, which increased only with multiparity. Conclusions. Use of analgesics and psychotropic drugs seems common in pregnancy. Our results indicate that lack of a support network, stressful life events, and lower status in society may predispose women to more drug use. GPs and midwives responsible for maternity care could take this into account when evaluating risk and gain for women and foetuses in the primary care setting. Text Iceland PubMed Central (PMC) Scandinavian Journal of Primary Health Care 32 3 139 145 |
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Original Article Axelsdottir, Thury O. Sigurdsson, Emil L. Gudmundsdottir, Anna M. Kristjansdottir, Hildur Sigurdsson, Johann A. Drug use during early pregnancy: Cross-sectional analysis from the Childbirth and Health Study in Primary Care in Iceland |
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Original Article |
description |
Objective. To analyse drug use in early pregnancy with special focus on socio-demographic factors associated with psychotropic and analgesic drug use. Design. Cross-sectional study. Setting and subjects. A total of 1765 women were invited via their local health care centres, and 1111 participated at 11–16 weeks of pregnancy by filling out a postal questionnaire concerning socio-demographic and obstetric background, stressful life events, and drug use. Main outcome measures. Drug use prior to and early on in pregnancy, socio-demographic factors, smoking, and adverse life events were investigated. Drug categories screened for were psychotropics (collective term for antidepressants, relaxants, and sleep medication), analgesics, hormones, nicotine, vitamins/minerals, and homeopathic medicine. Results. Drug use from the aforementioned drug categories, excluding vitamins/minerals and homeopathic medicine, was reduced by 18% during early pregnancy, compared with six months prior to conception (49% vs. 60%). Psychotropic drug use during early pregnancy was associated with elementary maternal education (p < 0.5), being unemployed (p < 0.001), being single/divorced/separated (p < 0.01), smoking prior to or during pregnancy (p < 0.01), forced to change job/move house (p < 0.001), and psychotropic drug use six months prior to pregnancy (p < 0.001). No items on the stressful life events scale were associated with increased analgesic use, which increased only with multiparity. Conclusions. Use of analgesics and psychotropic drugs seems common in pregnancy. Our results indicate that lack of a support network, stressful life events, and lower status in society may predispose women to more drug use. GPs and midwives responsible for maternity care could take this into account when evaluating risk and gain for women and foetuses in the primary care setting. |
format |
Text |
author |
Axelsdottir, Thury O. Sigurdsson, Emil L. Gudmundsdottir, Anna M. Kristjansdottir, Hildur Sigurdsson, Johann A. |
author_facet |
Axelsdottir, Thury O. Sigurdsson, Emil L. Gudmundsdottir, Anna M. Kristjansdottir, Hildur Sigurdsson, Johann A. |
author_sort |
Axelsdottir, Thury O. |
title |
Drug use during early pregnancy: Cross-sectional analysis from the Childbirth and Health Study in Primary Care in Iceland |
title_short |
Drug use during early pregnancy: Cross-sectional analysis from the Childbirth and Health Study in Primary Care in Iceland |
title_full |
Drug use during early pregnancy: Cross-sectional analysis from the Childbirth and Health Study in Primary Care in Iceland |
title_fullStr |
Drug use during early pregnancy: Cross-sectional analysis from the Childbirth and Health Study in Primary Care in Iceland |
title_full_unstemmed |
Drug use during early pregnancy: Cross-sectional analysis from the Childbirth and Health Study in Primary Care in Iceland |
title_sort |
drug use during early pregnancy: cross-sectional analysis from the childbirth and health study in primary care in iceland |
publisher |
Informa Healthcare |
publishDate |
2014 |
url |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4206559 http://www.ncbi.nlm.nih.gov/pubmed/25299613 https://doi.org/10.3109/02813432.2014.965884 |
genre |
Iceland |
genre_facet |
Iceland |
op_relation |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC http://www.ncbi.nlm.nih.gov/pubmed/25299613 http://dx.doi.org/10.3109/02813432.2014.965884 |
op_rights |
© 2014 The Author(s) http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) |
op_rightsnorm |
CC-BY-NC |
op_doi |
https://doi.org/10.3109/02813432.2014.965884 |
container_title |
Scandinavian Journal of Primary Health Care |
container_volume |
32 |
container_issue |
3 |
container_start_page |
139 |
op_container_end_page |
145 |
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1766041771412815872 |