A 6K-Deletion Variant of Salmonid Alphavirus Is Non-Viable but Can Be Rescued through RNA Recombination

• Published in: PLoS ONE
• Main Authors: Guo, Tz-Chun, Johansson, Daniel X., Haugland, Øyvind, Liljeström, Peter, Evensen, Øystein
• Format: Text
• Language: English
• Published: Public Library of Science 2014
• Subjects: Research Article; Sav’; Atlantic salmon
• Online Access: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4091863; http://www.ncbi.nlm.nih.gov/pubmed/25009976; https://doi.org/10.1371/journal.pone.0100184

Pancreas disease (PD) of Atlantic salmon is an emerging disease caused by Salmonid alphavirus (SAV) which mainly affects salmonid aquaculture in Western Europe. Although genome structure of SAV has been characterized and each individual viral protein has been identified, the role of 6K protein in vi...