Ontogenetic changes in skeletal muscle fiber type, fiber diameter and myoglobin concentration in the Northern elephant seal (Mirounga angustirostris)
Northern elephant seals (Mirounga angustirostris) (NES) are known to be deep, long-duration divers and to sustain long-repeated patterns of breath-hold, or apnea. Some phocid dives remain within the bounds of aerobic metabolism, accompanied by physiological responses inducing lung compression, brady...
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ftpubmed:oai:pubmedcentral.nih.gov:4050301 2023-05-15T16:05:20+02:00 Ontogenetic changes in skeletal muscle fiber type, fiber diameter and myoglobin concentration in the Northern elephant seal (Mirounga angustirostris) Moore, Colby D. Crocker, Daniel E. Fahlman, Andreas Moore, Michael J. Willoughby, Darryn S. Robbins, Kathleen A. Kanatous, Shane B. Trumble, Stephen J. 2014-06-10 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4050301 http://www.ncbi.nlm.nih.gov/pubmed/24959151 https://doi.org/10.3389/fphys.2014.00217 en eng Frontiers Media S.A. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC http://www.ncbi.nlm.nih.gov/pubmed/24959151 http://dx.doi.org/10.3389/fphys.2014.00217 Copyright © 2014 Moore, Crocker, Fahlman, Moore, Willoughby, Robbins, Kanatous and Trumble. http://creativecommons.org/licenses/by/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. CC-BY Physiology Text 2014 ftpubmed https://doi.org/10.3389/fphys.2014.00217 2014-06-29T00:37:07Z Northern elephant seals (Mirounga angustirostris) (NES) are known to be deep, long-duration divers and to sustain long-repeated patterns of breath-hold, or apnea. Some phocid dives remain within the bounds of aerobic metabolism, accompanied by physiological responses inducing lung compression, bradycardia, and peripheral vasoconstriction. Current data suggest an absence of type IIb fibers in pinniped locomotory musculature. To date, no fiber type data exist for NES, a consummate deep diver. In this study, NES were biopsied in the wild. Ontogenetic changes in skeletal muscle were revealed through succinate dehydrogenase (SDH) based fiber typing. Results indicated a predominance of uniformly shaped, large type I fibers and elevated myoglobin (Mb) concentrations in the longissimus dorsi (LD) muscle of adults. No type II muscle fibers were detected in any adult sampled. This was in contrast to the juvenile animals that demonstrated type II myosin in Western Blot analysis, indicative of an ontogenetic change in skeletal muscle with maturation. These data support previous hypotheses that the absence of type II fibers indicates reliance on aerobic metabolism during dives, as well as a depressed metabolic rate and low energy locomotion. We also suggest that the lack of type IIb fibers (adults) may provide a protection against ischemia reperfusion (IR) injury in vasoconstricted peripheral skeletal muscle. Text Elephant Seal Elephant Seals PubMed Central (PMC) Nes ENVELOPE(7.634,7.634,62.795,62.795) Nes’ ENVELOPE(44.681,44.681,66.600,66.600) Frontiers in Physiology 5 |
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English |
topic |
Physiology |
spellingShingle |
Physiology Moore, Colby D. Crocker, Daniel E. Fahlman, Andreas Moore, Michael J. Willoughby, Darryn S. Robbins, Kathleen A. Kanatous, Shane B. Trumble, Stephen J. Ontogenetic changes in skeletal muscle fiber type, fiber diameter and myoglobin concentration in the Northern elephant seal (Mirounga angustirostris) |
topic_facet |
Physiology |
description |
Northern elephant seals (Mirounga angustirostris) (NES) are known to be deep, long-duration divers and to sustain long-repeated patterns of breath-hold, or apnea. Some phocid dives remain within the bounds of aerobic metabolism, accompanied by physiological responses inducing lung compression, bradycardia, and peripheral vasoconstriction. Current data suggest an absence of type IIb fibers in pinniped locomotory musculature. To date, no fiber type data exist for NES, a consummate deep diver. In this study, NES were biopsied in the wild. Ontogenetic changes in skeletal muscle were revealed through succinate dehydrogenase (SDH) based fiber typing. Results indicated a predominance of uniformly shaped, large type I fibers and elevated myoglobin (Mb) concentrations in the longissimus dorsi (LD) muscle of adults. No type II muscle fibers were detected in any adult sampled. This was in contrast to the juvenile animals that demonstrated type II myosin in Western Blot analysis, indicative of an ontogenetic change in skeletal muscle with maturation. These data support previous hypotheses that the absence of type II fibers indicates reliance on aerobic metabolism during dives, as well as a depressed metabolic rate and low energy locomotion. We also suggest that the lack of type IIb fibers (adults) may provide a protection against ischemia reperfusion (IR) injury in vasoconstricted peripheral skeletal muscle. |
format |
Text |
author |
Moore, Colby D. Crocker, Daniel E. Fahlman, Andreas Moore, Michael J. Willoughby, Darryn S. Robbins, Kathleen A. Kanatous, Shane B. Trumble, Stephen J. |
author_facet |
Moore, Colby D. Crocker, Daniel E. Fahlman, Andreas Moore, Michael J. Willoughby, Darryn S. Robbins, Kathleen A. Kanatous, Shane B. Trumble, Stephen J. |
author_sort |
Moore, Colby D. |
title |
Ontogenetic changes in skeletal muscle fiber type, fiber diameter and myoglobin concentration in the Northern elephant seal (Mirounga angustirostris) |
title_short |
Ontogenetic changes in skeletal muscle fiber type, fiber diameter and myoglobin concentration in the Northern elephant seal (Mirounga angustirostris) |
title_full |
Ontogenetic changes in skeletal muscle fiber type, fiber diameter and myoglobin concentration in the Northern elephant seal (Mirounga angustirostris) |
title_fullStr |
Ontogenetic changes in skeletal muscle fiber type, fiber diameter and myoglobin concentration in the Northern elephant seal (Mirounga angustirostris) |
title_full_unstemmed |
Ontogenetic changes in skeletal muscle fiber type, fiber diameter and myoglobin concentration in the Northern elephant seal (Mirounga angustirostris) |
title_sort |
ontogenetic changes in skeletal muscle fiber type, fiber diameter and myoglobin concentration in the northern elephant seal (mirounga angustirostris) |
publisher |
Frontiers Media S.A. |
publishDate |
2014 |
url |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4050301 http://www.ncbi.nlm.nih.gov/pubmed/24959151 https://doi.org/10.3389/fphys.2014.00217 |
long_lat |
ENVELOPE(7.634,7.634,62.795,62.795) ENVELOPE(44.681,44.681,66.600,66.600) |
geographic |
Nes Nes’ |
geographic_facet |
Nes Nes’ |
genre |
Elephant Seal Elephant Seals |
genre_facet |
Elephant Seal Elephant Seals |
op_relation |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC http://www.ncbi.nlm.nih.gov/pubmed/24959151 http://dx.doi.org/10.3389/fphys.2014.00217 |
op_rights |
Copyright © 2014 Moore, Crocker, Fahlman, Moore, Willoughby, Robbins, Kanatous and Trumble. http://creativecommons.org/licenses/by/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
op_rightsnorm |
CC-BY |
op_doi |
https://doi.org/10.3389/fphys.2014.00217 |
container_title |
Frontiers in Physiology |
container_volume |
5 |
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1766401235439583232 |