Identification of Risk Factors for Plague in the West Nile Region of Uganda
Plague is an often fatal, primarily flea-borne rodent-associated zoonosis caused by Yersinia pestis. We sought to identify risk factors for plague by comparing villages with and without a history of human plague cases within a model-defined plague focus in the West Nile Region of Uganda. Although ra...
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ftpubmed:oai:pubmedcentral.nih.gov:4047728 2023-05-15T18:05:22+02:00 Identification of Risk Factors for Plague in the West Nile Region of Uganda Eisen, Rebecca J. MacMillan, Katherine Atiku, Linda A. Mpanga, Joseph T. Zielinski-Gutierrez, Emily Graham, Christine B. Boegler, Karen A. Enscore, Russell E. Gage, Kenneth L. 2014-06-04 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4047728/ http://www.ncbi.nlm.nih.gov/pubmed/24686743 https://doi.org/10.4269/ajtmh.14-0035 en eng The American Society of Tropical Medicine and Hygiene http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4047728/ http://www.ncbi.nlm.nih.gov/pubmed/24686743 http://dx.doi.org/10.4269/ajtmh.14-0035 ©The American Society of Tropical Medicine and Hygiene Articles Text 2014 ftpubmed https://doi.org/10.4269/ajtmh.14-0035 2015-06-07T00:04:19Z Plague is an often fatal, primarily flea-borne rodent-associated zoonosis caused by Yersinia pestis. We sought to identify risk factors for plague by comparing villages with and without a history of human plague cases within a model-defined plague focus in the West Nile Region of Uganda. Although rat (Rattus rattus) abundance was similar inside huts within case and control villages, contact rates between rats and humans (as measured by reported rat bites) and host-seeking flea loads were higher in case villages. In addition, compared with persons in control villages, persons in case villages more often reported sleeping on reed or straw mats, storing food in huts where persons sleep, owning dogs and allowing them into huts where persons sleep, storing garbage inside or near huts, and cooking in huts where persons sleep. Compared with persons in case villages, persons in control villages more commonly reported replacing thatch roofing, and growing coffee, tomatoes, onions, and melons in agricultural plots adjacent to their homesteads. Rodent and flea control practices, knowledge of plague, distance to clinics, and most care-seeking practices were similar between persons in case villages and persons in control villages. Our findings reinforce existing plague prevention recommendations and point to potentially advantageous local interventions. Text Rattus rattus PubMed Central (PMC) The American Journal of Tropical Medicine and Hygiene 90 6 1047 1058 |
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Articles Eisen, Rebecca J. MacMillan, Katherine Atiku, Linda A. Mpanga, Joseph T. Zielinski-Gutierrez, Emily Graham, Christine B. Boegler, Karen A. Enscore, Russell E. Gage, Kenneth L. Identification of Risk Factors for Plague in the West Nile Region of Uganda |
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Plague is an often fatal, primarily flea-borne rodent-associated zoonosis caused by Yersinia pestis. We sought to identify risk factors for plague by comparing villages with and without a history of human plague cases within a model-defined plague focus in the West Nile Region of Uganda. Although rat (Rattus rattus) abundance was similar inside huts within case and control villages, contact rates between rats and humans (as measured by reported rat bites) and host-seeking flea loads were higher in case villages. In addition, compared with persons in control villages, persons in case villages more often reported sleeping on reed or straw mats, storing food in huts where persons sleep, owning dogs and allowing them into huts where persons sleep, storing garbage inside or near huts, and cooking in huts where persons sleep. Compared with persons in case villages, persons in control villages more commonly reported replacing thatch roofing, and growing coffee, tomatoes, onions, and melons in agricultural plots adjacent to their homesteads. Rodent and flea control practices, knowledge of plague, distance to clinics, and most care-seeking practices were similar between persons in case villages and persons in control villages. Our findings reinforce existing plague prevention recommendations and point to potentially advantageous local interventions. |
format |
Text |
author |
Eisen, Rebecca J. MacMillan, Katherine Atiku, Linda A. Mpanga, Joseph T. Zielinski-Gutierrez, Emily Graham, Christine B. Boegler, Karen A. Enscore, Russell E. Gage, Kenneth L. |
author_facet |
Eisen, Rebecca J. MacMillan, Katherine Atiku, Linda A. Mpanga, Joseph T. Zielinski-Gutierrez, Emily Graham, Christine B. Boegler, Karen A. Enscore, Russell E. Gage, Kenneth L. |
author_sort |
Eisen, Rebecca J. |
title |
Identification of Risk Factors for Plague in the West Nile Region of Uganda |
title_short |
Identification of Risk Factors for Plague in the West Nile Region of Uganda |
title_full |
Identification of Risk Factors for Plague in the West Nile Region of Uganda |
title_fullStr |
Identification of Risk Factors for Plague in the West Nile Region of Uganda |
title_full_unstemmed |
Identification of Risk Factors for Plague in the West Nile Region of Uganda |
title_sort |
identification of risk factors for plague in the west nile region of uganda |
publisher |
The American Society of Tropical Medicine and Hygiene |
publishDate |
2014 |
url |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4047728/ http://www.ncbi.nlm.nih.gov/pubmed/24686743 https://doi.org/10.4269/ajtmh.14-0035 |
genre |
Rattus rattus |
genre_facet |
Rattus rattus |
op_relation |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4047728/ http://www.ncbi.nlm.nih.gov/pubmed/24686743 http://dx.doi.org/10.4269/ajtmh.14-0035 |
op_rights |
©The American Society of Tropical Medicine and Hygiene |
op_doi |
https://doi.org/10.4269/ajtmh.14-0035 |
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The American Journal of Tropical Medicine and Hygiene |
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90 |
container_issue |
6 |
container_start_page |
1047 |
op_container_end_page |
1058 |
_version_ |
1766176834653782016 |