Antiparasite treatments reduce humoral immunity and impact oxidative status in raptor nestlings
Parasites are natural stressors that may have multiple negative effects on their host as they usurp energy and nutrients and may lead to costly immune responses that may cause oxidative stress. At early stages, animals may be more sensitive to infectious organisms because of their rapid growth and p...
Published in: | Ecology and Evolution |
---|---|
Main Authors: | , , , , , , , , , , , , , , , |
Format: | Text |
Language: | English |
Published: |
Blackwell Publishing Ltd
2013
|
Subjects: | |
Online Access: | http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3892325 http://www.ncbi.nlm.nih.gov/pubmed/24455145 https://doi.org/10.1002/ece3.891 |
id |
ftpubmed:oai:pubmedcentral.nih.gov:3892325 |
---|---|
record_format |
openpolar |
spelling |
ftpubmed:oai:pubmedcentral.nih.gov:3892325 2023-05-15T13:00:43+02:00 Antiparasite treatments reduce humoral immunity and impact oxidative status in raptor nestlings Hanssen, Sveinn Are Bustnes, Jan Ove Schnug, Lisbeth Bourgeon, Sophie Johnsen, Trond Vidar Ballesteros, Manuel Sonne, Christian Herzke, Dorte Eulaers, Igor Jaspers, Veerle L B Covaci, Adrian Eens, Marcel Halley, Duncan J Moum, Truls Ims, Rolf Anker Erikstad, Kjell Einar 2013-12 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3892325 http://www.ncbi.nlm.nih.gov/pubmed/24455145 https://doi.org/10.1002/ece3.891 en eng Blackwell Publishing Ltd http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3892325 http://www.ncbi.nlm.nih.gov/pubmed/24455145 http://dx.doi.org/10.1002/ece3.891 © 2013 Published by John Wiley & Sons Ltd. http://creativecommons.org/licenses/by/2.5/ Re-use of this article is permitted in accordance with the Creative Commons Deed, Attribution 2.5, which does not permit commercial exploitation. CC-BY Original Research Text 2013 ftpubmed https://doi.org/10.1002/ece3.891 2014-01-26T01:36:36Z Parasites are natural stressors that may have multiple negative effects on their host as they usurp energy and nutrients and may lead to costly immune responses that may cause oxidative stress. At early stages, animals may be more sensitive to infectious organisms because of their rapid growth and partly immature immune system. The objective of this study was to explore effects of parasites by treating chicks of two raptor species (northern goshawk Accipiter gentilis and white-tailed sea eagle Haliaeetus albicilla) against both endoparasites (internal parasites) and ectoparasites (external parasites). Nests were either treated against ectoparasites by spraying with pyrethrin or left unsprayed as control nests. Within each nest, chicks were randomly orally treated with either an antihelminthic medication (fenbendazole) or sterile water as control treatment. We investigated treatment effects on plasma (1) total antioxidant capacity TAC (an index of nonenzymatic circulating antioxidant defenses), (2) total oxidant status TOS (a measure of plasmatic oxidants), and (3) immunoglobulin levels (a measure of humoral immune function). Treatment against ectoparasites led to a reduction in circulating immunoglobulin plasma levels in male chicks. TOS was higher when not receiving any parasite reduction treatment and when receiving both endo- and ectoparasitic reduction treatment compared with receiving only one treatment. TAC was higher in all treatment groups, when compared to controls. Despite the relatively low sample size, this experimental study suggests complex but similar relationships between treatment groups and oxidative status and immunoglobulin levels in two raptor species. Text Accipiter gentilis Haliaeetus albicilla Northern Goshawk PubMed Central (PMC) Tac ENVELOPE(-59.517,-59.517,-62.500,-62.500) Ecology and Evolution 3 16 5157 5166 |
institution |
Open Polar |
collection |
PubMed Central (PMC) |
op_collection_id |
ftpubmed |
language |
English |
topic |
Original Research |
spellingShingle |
Original Research Hanssen, Sveinn Are Bustnes, Jan Ove Schnug, Lisbeth Bourgeon, Sophie Johnsen, Trond Vidar Ballesteros, Manuel Sonne, Christian Herzke, Dorte Eulaers, Igor Jaspers, Veerle L B Covaci, Adrian Eens, Marcel Halley, Duncan J Moum, Truls Ims, Rolf Anker Erikstad, Kjell Einar Antiparasite treatments reduce humoral immunity and impact oxidative status in raptor nestlings |
topic_facet |
Original Research |
description |
Parasites are natural stressors that may have multiple negative effects on their host as they usurp energy and nutrients and may lead to costly immune responses that may cause oxidative stress. At early stages, animals may be more sensitive to infectious organisms because of their rapid growth and partly immature immune system. The objective of this study was to explore effects of parasites by treating chicks of two raptor species (northern goshawk Accipiter gentilis and white-tailed sea eagle Haliaeetus albicilla) against both endoparasites (internal parasites) and ectoparasites (external parasites). Nests were either treated against ectoparasites by spraying with pyrethrin or left unsprayed as control nests. Within each nest, chicks were randomly orally treated with either an antihelminthic medication (fenbendazole) or sterile water as control treatment. We investigated treatment effects on plasma (1) total antioxidant capacity TAC (an index of nonenzymatic circulating antioxidant defenses), (2) total oxidant status TOS (a measure of plasmatic oxidants), and (3) immunoglobulin levels (a measure of humoral immune function). Treatment against ectoparasites led to a reduction in circulating immunoglobulin plasma levels in male chicks. TOS was higher when not receiving any parasite reduction treatment and when receiving both endo- and ectoparasitic reduction treatment compared with receiving only one treatment. TAC was higher in all treatment groups, when compared to controls. Despite the relatively low sample size, this experimental study suggests complex but similar relationships between treatment groups and oxidative status and immunoglobulin levels in two raptor species. |
format |
Text |
author |
Hanssen, Sveinn Are Bustnes, Jan Ove Schnug, Lisbeth Bourgeon, Sophie Johnsen, Trond Vidar Ballesteros, Manuel Sonne, Christian Herzke, Dorte Eulaers, Igor Jaspers, Veerle L B Covaci, Adrian Eens, Marcel Halley, Duncan J Moum, Truls Ims, Rolf Anker Erikstad, Kjell Einar |
author_facet |
Hanssen, Sveinn Are Bustnes, Jan Ove Schnug, Lisbeth Bourgeon, Sophie Johnsen, Trond Vidar Ballesteros, Manuel Sonne, Christian Herzke, Dorte Eulaers, Igor Jaspers, Veerle L B Covaci, Adrian Eens, Marcel Halley, Duncan J Moum, Truls Ims, Rolf Anker Erikstad, Kjell Einar |
author_sort |
Hanssen, Sveinn Are |
title |
Antiparasite treatments reduce humoral immunity and impact oxidative status in raptor nestlings |
title_short |
Antiparasite treatments reduce humoral immunity and impact oxidative status in raptor nestlings |
title_full |
Antiparasite treatments reduce humoral immunity and impact oxidative status in raptor nestlings |
title_fullStr |
Antiparasite treatments reduce humoral immunity and impact oxidative status in raptor nestlings |
title_full_unstemmed |
Antiparasite treatments reduce humoral immunity and impact oxidative status in raptor nestlings |
title_sort |
antiparasite treatments reduce humoral immunity and impact oxidative status in raptor nestlings |
publisher |
Blackwell Publishing Ltd |
publishDate |
2013 |
url |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3892325 http://www.ncbi.nlm.nih.gov/pubmed/24455145 https://doi.org/10.1002/ece3.891 |
long_lat |
ENVELOPE(-59.517,-59.517,-62.500,-62.500) |
geographic |
Tac |
geographic_facet |
Tac |
genre |
Accipiter gentilis Haliaeetus albicilla Northern Goshawk |
genre_facet |
Accipiter gentilis Haliaeetus albicilla Northern Goshawk |
op_relation |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3892325 http://www.ncbi.nlm.nih.gov/pubmed/24455145 http://dx.doi.org/10.1002/ece3.891 |
op_rights |
© 2013 Published by John Wiley & Sons Ltd. http://creativecommons.org/licenses/by/2.5/ Re-use of this article is permitted in accordance with the Creative Commons Deed, Attribution 2.5, which does not permit commercial exploitation. |
op_rightsnorm |
CC-BY |
op_doi |
https://doi.org/10.1002/ece3.891 |
container_title |
Ecology and Evolution |
container_volume |
3 |
container_issue |
16 |
container_start_page |
5157 |
op_container_end_page |
5166 |
_version_ |
1766258596139499520 |