Effects of Age and Sex on Estimated Diabetes Prevalence Using Different Diagnostic Criteria: The Tromsø OGTT Study
HbA1c 6.5% has recently been recommended as an alternative diagnostic criterion for diabetes. The aims of the study were to evaluate the effects of age, sex, and other factors on prevalence of diabetes and to compare risk profiles of subjects with diabetes when defined by HbA1c and glucose criteria....
Published in: | International Journal of Endocrinology |
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Online Access: | http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3556443 http://www.ncbi.nlm.nih.gov/pubmed/23365572 https://doi.org/10.1155/2013/613475 |
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ftpubmed:oai:pubmedcentral.nih.gov:3556443 2023-05-15T18:34:23+02:00 Effects of Age and Sex on Estimated Diabetes Prevalence Using Different Diagnostic Criteria: The Tromsø OGTT Study Hutchinson, Moira Strand Joakimsen, Ragnar Martin Njølstad, Inger Schirmer, Henrik Figenschau, Yngve Svartberg, Johan Jorde, Rolf 2013 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3556443 http://www.ncbi.nlm.nih.gov/pubmed/23365572 https://doi.org/10.1155/2013/613475 en eng Hindawi Publishing Corporation http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3556443 http://www.ncbi.nlm.nih.gov/pubmed/23365572 http://dx.doi.org/10.1155/2013/613475 Copyright © 2013 Moira Strand Hutchinson et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. CC-BY Research Article Text 2013 ftpubmed https://doi.org/10.1155/2013/613475 2013-09-04T19:00:32Z HbA1c 6.5% has recently been recommended as an alternative diagnostic criterion for diabetes. The aims of the study were to evaluate the effects of age, sex, and other factors on prevalence of diabetes and to compare risk profiles of subjects with diabetes when defined by HbA1c and glucose criteria. Subjects were recruited among participants in the longitudinal population-based Tromsø Study. HbA1c, fasting plasma glucose, and 2-hour plasma glucose were measured in 3,476 subjects. In total, 294 subjects met one or more of the diagnostic criteria for diabetes; 95 met the HbA1c criterion only, 130 met the glucose criteria only, and 69 met both. Among subjects with diabetes detected by glucose criteria (regardless of HbA1c), isolated raised 2-hour plasma glucose was more common in subjects aged ≥ 60 years as compared to younger subjects and in elderly women as compared to elderly men. Subjects with diabetes detected by glucose criteria only had worse cardiometabolic risk profiles than those detected by HbA1c only. In conclusion, the current HbA1c and glucose criteria defined different subjects with diabetes with only modest overlap. Among a substantial proportion of elderly subjects, and especially elderly women, the 2-hour plasma glucose was the only abnormal value. Text Tromsø PubMed Central (PMC) Tromsø International Journal of Endocrinology 2013 1 9 |
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Research Article Hutchinson, Moira Strand Joakimsen, Ragnar Martin Njølstad, Inger Schirmer, Henrik Figenschau, Yngve Svartberg, Johan Jorde, Rolf Effects of Age and Sex on Estimated Diabetes Prevalence Using Different Diagnostic Criteria: The Tromsø OGTT Study |
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Research Article |
description |
HbA1c 6.5% has recently been recommended as an alternative diagnostic criterion for diabetes. The aims of the study were to evaluate the effects of age, sex, and other factors on prevalence of diabetes and to compare risk profiles of subjects with diabetes when defined by HbA1c and glucose criteria. Subjects were recruited among participants in the longitudinal population-based Tromsø Study. HbA1c, fasting plasma glucose, and 2-hour plasma glucose were measured in 3,476 subjects. In total, 294 subjects met one or more of the diagnostic criteria for diabetes; 95 met the HbA1c criterion only, 130 met the glucose criteria only, and 69 met both. Among subjects with diabetes detected by glucose criteria (regardless of HbA1c), isolated raised 2-hour plasma glucose was more common in subjects aged ≥ 60 years as compared to younger subjects and in elderly women as compared to elderly men. Subjects with diabetes detected by glucose criteria only had worse cardiometabolic risk profiles than those detected by HbA1c only. In conclusion, the current HbA1c and glucose criteria defined different subjects with diabetes with only modest overlap. Among a substantial proportion of elderly subjects, and especially elderly women, the 2-hour plasma glucose was the only abnormal value. |
format |
Text |
author |
Hutchinson, Moira Strand Joakimsen, Ragnar Martin Njølstad, Inger Schirmer, Henrik Figenschau, Yngve Svartberg, Johan Jorde, Rolf |
author_facet |
Hutchinson, Moira Strand Joakimsen, Ragnar Martin Njølstad, Inger Schirmer, Henrik Figenschau, Yngve Svartberg, Johan Jorde, Rolf |
author_sort |
Hutchinson, Moira Strand |
title |
Effects of Age and Sex on Estimated Diabetes Prevalence Using Different Diagnostic Criteria: The Tromsø OGTT Study |
title_short |
Effects of Age and Sex on Estimated Diabetes Prevalence Using Different Diagnostic Criteria: The Tromsø OGTT Study |
title_full |
Effects of Age and Sex on Estimated Diabetes Prevalence Using Different Diagnostic Criteria: The Tromsø OGTT Study |
title_fullStr |
Effects of Age and Sex on Estimated Diabetes Prevalence Using Different Diagnostic Criteria: The Tromsø OGTT Study |
title_full_unstemmed |
Effects of Age and Sex on Estimated Diabetes Prevalence Using Different Diagnostic Criteria: The Tromsø OGTT Study |
title_sort |
effects of age and sex on estimated diabetes prevalence using different diagnostic criteria: the tromsø ogtt study |
publisher |
Hindawi Publishing Corporation |
publishDate |
2013 |
url |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3556443 http://www.ncbi.nlm.nih.gov/pubmed/23365572 https://doi.org/10.1155/2013/613475 |
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Tromsø |
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Tromsø |
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Tromsø |
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Tromsø |
op_relation |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3556443 http://www.ncbi.nlm.nih.gov/pubmed/23365572 http://dx.doi.org/10.1155/2013/613475 |
op_rights |
Copyright © 2013 Moira Strand Hutchinson et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
op_rightsnorm |
CC-BY |
op_doi |
https://doi.org/10.1155/2013/613475 |
container_title |
International Journal of Endocrinology |
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2013 |
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1 |
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9 |
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1766219110297894912 |