Genetic Analysis of Avian Influenza Viruses: Cocirculation of Avian Influenza Viruses with Allele A and B Nonstructural Gene in Northern Pintail (Anas acuta) Ducks Wintering in Japan
The pandemic influenza virus strains of 1918 (H1N1), 1957 (H2N2), 1968 (H3N2), and 2009 (H1N1) have genes related to avian influenza viruses (AIVs). The nonstructural (NS) gene of AIVs plays a significant role in host-viral interaction. However, little is known about the degree of diversity of this...
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ftpubmed:oai:pubmedcentral.nih.gov:3540751 2023-05-15T13:24:47+02:00 Genetic Analysis of Avian Influenza Viruses: Cocirculation of Avian Influenza Viruses with Allele A and B Nonstructural Gene in Northern Pintail (Anas acuta) Ducks Wintering in Japan Jahangir, Alam Ruenphet, Sakchai Sultana, Nadia Shoham, Dany Takehara, Kazuaki 2012 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3540751 http://www.ncbi.nlm.nih.gov/pubmed/23320157 https://doi.org/10.1155/2012/847505 en eng Hindawi Publishing Corporation http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3540751 http://www.ncbi.nlm.nih.gov/pubmed/23320157 http://dx.doi.org/10.1155/2012/847505 Copyright © 2012 Alam Jahangir et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. CC-BY Research Article Text 2012 ftpubmed https://doi.org/10.1155/2012/847505 2013-09-04T18:10:27Z The pandemic influenza virus strains of 1918 (H1N1), 1957 (H2N2), 1968 (H3N2), and 2009 (H1N1) have genes related to avian influenza viruses (AIVs). The nonstructural (NS) gene of AIVs plays a significant role in host-viral interaction. However, little is known about the degree of diversity of this gene in Northern pintail (Anas acuta) ducks wintering in Japan. This study describes characteristics of pintail-originated H1N1, H1N2, H1N3, H5N2, H5N3, H5N9, and H7N7 viruses. Most of the viruses were revealed to be avian strains and not related to pandemic and seasonal flu strains. Nevertheless, the NP genes of 62.5% (5/8) viruses were found closely related to a A/swine/Korea/C12/08, indicating exchange of genetic material and ongoing mammalian-linked evolution of AIVs. Besides, all the viruses, except Aomori/422/07 H1N1, contain PSIQSR∗GLF motif usually found in avian, porcine, and human H1 strains. The Aomori/422/07 H1N1 has a PSVQSR∗GLF motif identical to a North American strain. This findings linked to an important intercontinental, Asian-American biogeographical interface. Phylogenetically all the viruses were clustered in Eurasian lineage. Cocirculation of allele A and B (NS gene) viruses was evident in the study implying the existence of a wide reservoir of influenza A viruses in pintail wintering in Japan. Text Anas acuta PubMed Central (PMC) Influenza Research and Treatment 2012 1 10 |
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Research Article Jahangir, Alam Ruenphet, Sakchai Sultana, Nadia Shoham, Dany Takehara, Kazuaki Genetic Analysis of Avian Influenza Viruses: Cocirculation of Avian Influenza Viruses with Allele A and B Nonstructural Gene in Northern Pintail (Anas acuta) Ducks Wintering in Japan |
topic_facet |
Research Article |
description |
The pandemic influenza virus strains of 1918 (H1N1), 1957 (H2N2), 1968 (H3N2), and 2009 (H1N1) have genes related to avian influenza viruses (AIVs). The nonstructural (NS) gene of AIVs plays a significant role in host-viral interaction. However, little is known about the degree of diversity of this gene in Northern pintail (Anas acuta) ducks wintering in Japan. This study describes characteristics of pintail-originated H1N1, H1N2, H1N3, H5N2, H5N3, H5N9, and H7N7 viruses. Most of the viruses were revealed to be avian strains and not related to pandemic and seasonal flu strains. Nevertheless, the NP genes of 62.5% (5/8) viruses were found closely related to a A/swine/Korea/C12/08, indicating exchange of genetic material and ongoing mammalian-linked evolution of AIVs. Besides, all the viruses, except Aomori/422/07 H1N1, contain PSIQSR∗GLF motif usually found in avian, porcine, and human H1 strains. The Aomori/422/07 H1N1 has a PSVQSR∗GLF motif identical to a North American strain. This findings linked to an important intercontinental, Asian-American biogeographical interface. Phylogenetically all the viruses were clustered in Eurasian lineage. Cocirculation of allele A and B (NS gene) viruses was evident in the study implying the existence of a wide reservoir of influenza A viruses in pintail wintering in Japan. |
format |
Text |
author |
Jahangir, Alam Ruenphet, Sakchai Sultana, Nadia Shoham, Dany Takehara, Kazuaki |
author_facet |
Jahangir, Alam Ruenphet, Sakchai Sultana, Nadia Shoham, Dany Takehara, Kazuaki |
author_sort |
Jahangir, Alam |
title |
Genetic Analysis of Avian Influenza Viruses: Cocirculation of Avian Influenza Viruses with Allele A and B Nonstructural Gene in Northern Pintail (Anas acuta) Ducks Wintering in Japan |
title_short |
Genetic Analysis of Avian Influenza Viruses: Cocirculation of Avian Influenza Viruses with Allele A and B Nonstructural Gene in Northern Pintail (Anas acuta) Ducks Wintering in Japan |
title_full |
Genetic Analysis of Avian Influenza Viruses: Cocirculation of Avian Influenza Viruses with Allele A and B Nonstructural Gene in Northern Pintail (Anas acuta) Ducks Wintering in Japan |
title_fullStr |
Genetic Analysis of Avian Influenza Viruses: Cocirculation of Avian Influenza Viruses with Allele A and B Nonstructural Gene in Northern Pintail (Anas acuta) Ducks Wintering in Japan |
title_full_unstemmed |
Genetic Analysis of Avian Influenza Viruses: Cocirculation of Avian Influenza Viruses with Allele A and B Nonstructural Gene in Northern Pintail (Anas acuta) Ducks Wintering in Japan |
title_sort |
genetic analysis of avian influenza viruses: cocirculation of avian influenza viruses with allele a and b nonstructural gene in northern pintail (anas acuta) ducks wintering in japan |
publisher |
Hindawi Publishing Corporation |
publishDate |
2012 |
url |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3540751 http://www.ncbi.nlm.nih.gov/pubmed/23320157 https://doi.org/10.1155/2012/847505 |
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Anas acuta |
genre_facet |
Anas acuta |
op_relation |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3540751 http://www.ncbi.nlm.nih.gov/pubmed/23320157 http://dx.doi.org/10.1155/2012/847505 |
op_rights |
Copyright © 2012 Alam Jahangir et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
op_rightsnorm |
CC-BY |
op_doi |
https://doi.org/10.1155/2012/847505 |
container_title |
Influenza Research and Treatment |
container_volume |
2012 |
container_start_page |
1 |
op_container_end_page |
10 |
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1766381616452599808 |