Multiple Kisspeptin Receptors in Early Osteichthyans Provide New Insights into the Evolution of This Receptor Family

• Published in: PLoS ONE
• Main Authors: Pasquier, Jérémy, Lafont, Anne-Gaëlle, Jeng, Shan-Ru, Morini, Marina, Dirks, Ron, van den Thillart, Guido, Tomkiewicz, Jonna, Tostivint, Hervé, Chang, Ching-Fong, Rousseau, Karine, Dufour, Sylvie
• Format: Text
• Language: English
• Published: Public Library of Science 2012
• Subjects: Research Article; Gar’; European eel
• Online Access: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3502363; http://www.ncbi.nlm.nih.gov/pubmed/23185286; https://doi.org/10.1371/journal.pone.0048931

Deorphanization of GPR54 receptor a decade ago led to the characterization of the kisspeptin receptor (Kissr) in mammals and the discovery of its major role in the brain control of reproduction. While a single gene encodes for Kissr in eutherian mammals including human, other vertebrates present a v...