Antarctic Harsh Environment as Natural Stress Model: Impact on Salivary Immunoglobulins, Transforming Growth Factor-β and Cortisol Level

• Published in: Indian Journal of Clinical Biochemistry
• Main Authors: Mishra, K. P., Yadav, A. P., Ganju, Lilly
• Format: Text
• Language: English
• Published: Springer-Verlag 2012
• Subjects: Original Article; Antarctic; Indian; Maitri; Southern Ocean; The Antarctic; Antarc*; Antarctica
• Online Access: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3477453; http://www.ncbi.nlm.nih.gov/pubmed/24082460; https://doi.org/10.1007/s12291-012-0213-z

The Antarctic continent on the planet Earth is full of environmental extremes. It is considered as natural stress model. Therefore, the present study examined the effect of harsh environment on the certain salivary markers of 28th Indian Antarctic expeditioners. Thirty healthy men and women (median age 36 year; range 22–61 year) participated in this study. Parameters measured were salivary IgA (SIgA), IgM (SIgM), TGF-β and cortisol level at three different time points: (I) before leaving India on 26th October 2008 for base line level; (II) after 1 month on-board journey on 31st January 2009 in Southern Ocean and (III) after 1 month staying at Maitri, Antarctica on 3rd March 2009. Our observation indicated that Ship borne journey and Antarctic environment increased the SIgA levels while that of SIgM level was not altered on-board but decreased by staying for 1 month at Antarctica. No significant alteration was found in the TGF-β and cortisol level at any point of time. The present study concluded that ship borne journey and Antarctic environment may induce the SIgA level while SIgM level decreased in environmental extremes of Antarctica.