Vitamin D deficiency among northern Native Peoples: a real or apparent problem?
Vitamin D deficiency seems to be common among northern Native peoples, notably Inuit and Amerindians. It has usually been attributed to: (1) higher latitudes that prevent vitamin D synthesis most of the year; (2) darker skin that blocks solar UVB; and (3) fewer dietary sources of vitamin D. Although...
Published in: | International Journal of Circumpolar Health |
---|---|
Main Author: | |
Format: | Text |
Language: | English |
Published: |
Co-Action Publishing
2012
|
Subjects: | |
Online Access: | http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3417586 http://www.ncbi.nlm.nih.gov/pubmed/22456053 https://doi.org/10.3402/IJCH.v71i0.18001 |
id |
ftpubmed:oai:pubmedcentral.nih.gov:3417586 |
---|---|
record_format |
openpolar |
spelling |
ftpubmed:oai:pubmedcentral.nih.gov:3417586 2023-05-15T16:54:59+02:00 Vitamin D deficiency among northern Native Peoples: a real or apparent problem? Frost, Peter 2012-03-19 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3417586 http://www.ncbi.nlm.nih.gov/pubmed/22456053 https://doi.org/10.3402/IJCH.v71i0.18001 en eng Co-Action Publishing http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3417586 http://www.ncbi.nlm.nih.gov/pubmed/22456053 http://dx.doi.org/10.3402/IJCH.v71i0.18001 © 2012 Peter Frost http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-Noncommercial 3.0 Unported License, permitting all non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. CC-BY-NC Circumpolar Voices Text 2012 ftpubmed https://doi.org/10.3402/IJCH.v71i0.18001 2013-09-04T11:24:23Z Vitamin D deficiency seems to be common among northern Native peoples, notably Inuit and Amerindians. It has usually been attributed to: (1) higher latitudes that prevent vitamin D synthesis most of the year; (2) darker skin that blocks solar UVB; and (3) fewer dietary sources of vitamin D. Although vitamin D levels are clearly lower among northern Natives, it is less clear that these lower levels indicate a deficiency. The above factors predate European contact, yet pre-Columbian skeletons show few signs of rickets—the most visible sign of vitamin D deficiency. Furthermore, because northern Natives have long inhabited high latitudes, natural selection should have progressively reduced their vitamin D requirements. There is in fact evidence that the Inuit have compensated for decreased production of vitamin D through increased conversion to its most active form and through receptors that bind more effectively. Thus, when diagnosing vitamin D deficiency in these populations, we should not use norms that were originally developed for European-descended populations who produce this vitamin more easily and have adapted accordingly.1 Text inuit PubMed Central (PMC) International Journal of Circumpolar Health 71 1 18001 |
institution |
Open Polar |
collection |
PubMed Central (PMC) |
op_collection_id |
ftpubmed |
language |
English |
topic |
Circumpolar Voices |
spellingShingle |
Circumpolar Voices Frost, Peter Vitamin D deficiency among northern Native Peoples: a real or apparent problem? |
topic_facet |
Circumpolar Voices |
description |
Vitamin D deficiency seems to be common among northern Native peoples, notably Inuit and Amerindians. It has usually been attributed to: (1) higher latitudes that prevent vitamin D synthesis most of the year; (2) darker skin that blocks solar UVB; and (3) fewer dietary sources of vitamin D. Although vitamin D levels are clearly lower among northern Natives, it is less clear that these lower levels indicate a deficiency. The above factors predate European contact, yet pre-Columbian skeletons show few signs of rickets—the most visible sign of vitamin D deficiency. Furthermore, because northern Natives have long inhabited high latitudes, natural selection should have progressively reduced their vitamin D requirements. There is in fact evidence that the Inuit have compensated for decreased production of vitamin D through increased conversion to its most active form and through receptors that bind more effectively. Thus, when diagnosing vitamin D deficiency in these populations, we should not use norms that were originally developed for European-descended populations who produce this vitamin more easily and have adapted accordingly.1 |
format |
Text |
author |
Frost, Peter |
author_facet |
Frost, Peter |
author_sort |
Frost, Peter |
title |
Vitamin D deficiency among northern Native Peoples: a real or apparent problem? |
title_short |
Vitamin D deficiency among northern Native Peoples: a real or apparent problem? |
title_full |
Vitamin D deficiency among northern Native Peoples: a real or apparent problem? |
title_fullStr |
Vitamin D deficiency among northern Native Peoples: a real or apparent problem? |
title_full_unstemmed |
Vitamin D deficiency among northern Native Peoples: a real or apparent problem? |
title_sort |
vitamin d deficiency among northern native peoples: a real or apparent problem? |
publisher |
Co-Action Publishing |
publishDate |
2012 |
url |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3417586 http://www.ncbi.nlm.nih.gov/pubmed/22456053 https://doi.org/10.3402/IJCH.v71i0.18001 |
genre |
inuit |
genre_facet |
inuit |
op_relation |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3417586 http://www.ncbi.nlm.nih.gov/pubmed/22456053 http://dx.doi.org/10.3402/IJCH.v71i0.18001 |
op_rights |
© 2012 Peter Frost http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-Noncommercial 3.0 Unported License, permitting all non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
op_rightsnorm |
CC-BY-NC |
op_doi |
https://doi.org/10.3402/IJCH.v71i0.18001 |
container_title |
International Journal of Circumpolar Health |
container_volume |
71 |
container_issue |
1 |
container_start_page |
18001 |
_version_ |
1766045940163018752 |