Orthopoxvirus DNA in Eurasian Lynx, Sweden
Cowpox virus, which has been used to protect humans against smallpox but may cause severe disease in immunocompromised persons, has reemerged in humans, domestic cats, and other animal species in Europe. Orthopoxvirus (OPV) DNA was detected in tissues (lung, kidney, spleen) in 24 (9%) of 263 free-ra...
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ftpubmed:oai:pubmedcentral.nih.gov:3377389 2023-05-15T18:50:23+02:00 Orthopoxvirus DNA in Eurasian Lynx, Sweden Tryland, Morten Okeke, Malachy Ifeanyi af Segerstad, Carl Hård Mörner, Torsten Traavik, Terje Ryser-Degiorgis, Marie-Pierre 2011-04 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3377389 http://www.ncbi.nlm.nih.gov/pubmed/21470451 https://doi.org/10.3201/eid1704.091899 en eng Centers for Disease Control and Prevention http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3377389 http://www.ncbi.nlm.nih.gov/pubmed/21470451 http://dx.doi.org/10.3201/eid1704.091899 Research Text 2011 ftpubmed https://doi.org/10.3201/eid1704.091899 2013-09-04T08:51:38Z Cowpox virus, which has been used to protect humans against smallpox but may cause severe disease in immunocompromised persons, has reemerged in humans, domestic cats, and other animal species in Europe. Orthopoxvirus (OPV) DNA was detected in tissues (lung, kidney, spleen) in 24 (9%) of 263 free-ranging Eurasian lynx (Lynx lynx) from Sweden. Thymidine kinase gene amplicon sequences (339 bp) from 21 lynx were all identical to those from cowpox virus isolated from a person in Norway and phylogenetically closer to monkeypox virus than to vaccinia virus and isolates from 2 persons with cowpox virus in Sweden. Prevalence was higher among animals from regions with dense, rather than rural, human populations. Lynx are probably exposed to OPV through predation on small mammal reservoir species. We conclude that OPV is widely distributed in Sweden and may represent a threat to humans. Further studies are needed to verify whether this lynx OPV is cowpox virus. Text Lynx Lynx lynx lynx PubMed Central (PMC) Norway Emerging Infectious Diseases 17 4 626 632 |
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Research Tryland, Morten Okeke, Malachy Ifeanyi af Segerstad, Carl Hård Mörner, Torsten Traavik, Terje Ryser-Degiorgis, Marie-Pierre Orthopoxvirus DNA in Eurasian Lynx, Sweden |
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Research |
description |
Cowpox virus, which has been used to protect humans against smallpox but may cause severe disease in immunocompromised persons, has reemerged in humans, domestic cats, and other animal species in Europe. Orthopoxvirus (OPV) DNA was detected in tissues (lung, kidney, spleen) in 24 (9%) of 263 free-ranging Eurasian lynx (Lynx lynx) from Sweden. Thymidine kinase gene amplicon sequences (339 bp) from 21 lynx were all identical to those from cowpox virus isolated from a person in Norway and phylogenetically closer to monkeypox virus than to vaccinia virus and isolates from 2 persons with cowpox virus in Sweden. Prevalence was higher among animals from regions with dense, rather than rural, human populations. Lynx are probably exposed to OPV through predation on small mammal reservoir species. We conclude that OPV is widely distributed in Sweden and may represent a threat to humans. Further studies are needed to verify whether this lynx OPV is cowpox virus. |
format |
Text |
author |
Tryland, Morten Okeke, Malachy Ifeanyi af Segerstad, Carl Hård Mörner, Torsten Traavik, Terje Ryser-Degiorgis, Marie-Pierre |
author_facet |
Tryland, Morten Okeke, Malachy Ifeanyi af Segerstad, Carl Hård Mörner, Torsten Traavik, Terje Ryser-Degiorgis, Marie-Pierre |
author_sort |
Tryland, Morten |
title |
Orthopoxvirus DNA in Eurasian Lynx, Sweden |
title_short |
Orthopoxvirus DNA in Eurasian Lynx, Sweden |
title_full |
Orthopoxvirus DNA in Eurasian Lynx, Sweden |
title_fullStr |
Orthopoxvirus DNA in Eurasian Lynx, Sweden |
title_full_unstemmed |
Orthopoxvirus DNA in Eurasian Lynx, Sweden |
title_sort |
orthopoxvirus dna in eurasian lynx, sweden |
publisher |
Centers for Disease Control and Prevention |
publishDate |
2011 |
url |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3377389 http://www.ncbi.nlm.nih.gov/pubmed/21470451 https://doi.org/10.3201/eid1704.091899 |
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Norway |
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Norway |
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Lynx Lynx lynx lynx |
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Lynx Lynx lynx lynx |
op_relation |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3377389 http://www.ncbi.nlm.nih.gov/pubmed/21470451 http://dx.doi.org/10.3201/eid1704.091899 |
op_doi |
https://doi.org/10.3201/eid1704.091899 |
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Emerging Infectious Diseases |
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17 |
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4 |
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632 |
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1766244104214151168 |