Functional characterization and localization of a gill-specific claudin isoform in Atlantic salmon

• Published in: American Journal of Physiology-Regulatory, Integrative and Comparative Physiology
• Main Authors: Engelund, M. B., Yu, A. S. L., Li, J., Madsen, S. S., Færgeman, N. J., Tipsmark, C. K.
• Format: Text
• Language: English
• Published: American Physiological Society 2012
• Subjects: Fluid and Electrolyte Homeostasis; Darby; Atlantic salmon; Salmo salar
• Online Access: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3349389; http://www.ncbi.nlm.nih.gov/pubmed/21975646; https://doi.org/10.1152/ajpregu.00286.2011

Claudins are the major determinants of paracellular epithelial permeability in multicellular organisms. In Atlantic salmon (Salmo salar L.), we previously found that mRNA expression of the abundant gill-specific claudin 30 decreases during seawater (SW) acclimation, suggesting that this claudin is a...