Phylogenetic Distinctiveness of Middle Eastern and Southeast Asian Village Dog Y Chromosomes Illuminates Dog Origins
Modern genetic samples are commonly used to trace dog origins, which entails untested assumptions that village dogs reflect indigenous ancestry or that breed origins can be reliably traced to particular regions. We used high-resolution Y chromosome markers (SNP and STR) and mitochondrial DNA to anal...
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ftpubmed:oai:pubmedcentral.nih.gov:3237445 2023-05-15T15:51:03+02:00 Phylogenetic Distinctiveness of Middle Eastern and Southeast Asian Village Dog Y Chromosomes Illuminates Dog Origins Brown, Sarah K. Pedersen, Niels C. Jafarishorijeh, Sardar Bannasch, Danika L. Ahrens, Kristen D. Wu, Jui-Te Okon, Michaella Sacks, Benjamin N. 2011-12-14 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3237445 http://www.ncbi.nlm.nih.gov/pubmed/22194840 https://doi.org/10.1371/journal.pone.0028496 en eng Public Library of Science http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3237445 http://www.ncbi.nlm.nih.gov/pubmed/22194840 http://dx.doi.org/10.1371/journal.pone.0028496 Brown et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. CC-BY Research Article Text 2011 ftpubmed https://doi.org/10.1371/journal.pone.0028496 2013-09-03T23:55:40Z Modern genetic samples are commonly used to trace dog origins, which entails untested assumptions that village dogs reflect indigenous ancestry or that breed origins can be reliably traced to particular regions. We used high-resolution Y chromosome markers (SNP and STR) and mitochondrial DNA to analyze 495 village dogs/dingoes from the Middle East and Southeast Asia, along with 138 dogs from >35 modern breeds to 1) assess genetic divergence between Middle Eastern and Southeast Asian village dogs and their phylogenetic affinities to Australian dingoes and gray wolves (Canis lupus) and 2) compare the genetic affinities of modern breeds to regional indigenous village dog populations. The Y chromosome markers indicated that village dogs in the two regions corresponded to reciprocally monophyletic clades, reflecting several to many thousand years divergence, predating the Neolithic ages, and indicating long-indigenous roots to those regions. As expected, breeds of the Middle East and East Asia clustered within the respective regional village dog clade. Australian dingoes also clustered in the Southeast Asian clade. However, the European and American breeds clustered almost entirely within the Southeast Asian clade, even sharing many haplotypes, suggesting a substantial and recent influence of East Asian dogs in the creation of European breeds. Comparison to 818 published breed dog Y STR haplotypes confirmed this conclusion and indicated that some African breeds reflect another distinct patrilineal origin. The lower-resolution mtDNA marker consistently supported Y-chromosome results. Both marker types confirmed previous findings of higher genetic diversity in dogs from Southeast Asia than the Middle East. Our findings demonstrate the importance of village dogs as windows into the past and provide a reference against which ancient DNA can be used to further elucidate origins and spread of the domestic dog. Text Canis lupus PubMed Central (PMC) The ''Y'' ENVELOPE(-112.453,-112.453,57.591,57.591) PLoS ONE 6 12 e28496 |
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Research Article Brown, Sarah K. Pedersen, Niels C. Jafarishorijeh, Sardar Bannasch, Danika L. Ahrens, Kristen D. Wu, Jui-Te Okon, Michaella Sacks, Benjamin N. Phylogenetic Distinctiveness of Middle Eastern and Southeast Asian Village Dog Y Chromosomes Illuminates Dog Origins |
topic_facet |
Research Article |
description |
Modern genetic samples are commonly used to trace dog origins, which entails untested assumptions that village dogs reflect indigenous ancestry or that breed origins can be reliably traced to particular regions. We used high-resolution Y chromosome markers (SNP and STR) and mitochondrial DNA to analyze 495 village dogs/dingoes from the Middle East and Southeast Asia, along with 138 dogs from >35 modern breeds to 1) assess genetic divergence between Middle Eastern and Southeast Asian village dogs and their phylogenetic affinities to Australian dingoes and gray wolves (Canis lupus) and 2) compare the genetic affinities of modern breeds to regional indigenous village dog populations. The Y chromosome markers indicated that village dogs in the two regions corresponded to reciprocally monophyletic clades, reflecting several to many thousand years divergence, predating the Neolithic ages, and indicating long-indigenous roots to those regions. As expected, breeds of the Middle East and East Asia clustered within the respective regional village dog clade. Australian dingoes also clustered in the Southeast Asian clade. However, the European and American breeds clustered almost entirely within the Southeast Asian clade, even sharing many haplotypes, suggesting a substantial and recent influence of East Asian dogs in the creation of European breeds. Comparison to 818 published breed dog Y STR haplotypes confirmed this conclusion and indicated that some African breeds reflect another distinct patrilineal origin. The lower-resolution mtDNA marker consistently supported Y-chromosome results. Both marker types confirmed previous findings of higher genetic diversity in dogs from Southeast Asia than the Middle East. Our findings demonstrate the importance of village dogs as windows into the past and provide a reference against which ancient DNA can be used to further elucidate origins and spread of the domestic dog. |
format |
Text |
author |
Brown, Sarah K. Pedersen, Niels C. Jafarishorijeh, Sardar Bannasch, Danika L. Ahrens, Kristen D. Wu, Jui-Te Okon, Michaella Sacks, Benjamin N. |
author_facet |
Brown, Sarah K. Pedersen, Niels C. Jafarishorijeh, Sardar Bannasch, Danika L. Ahrens, Kristen D. Wu, Jui-Te Okon, Michaella Sacks, Benjamin N. |
author_sort |
Brown, Sarah K. |
title |
Phylogenetic Distinctiveness of Middle Eastern and Southeast Asian Village Dog Y Chromosomes Illuminates Dog Origins |
title_short |
Phylogenetic Distinctiveness of Middle Eastern and Southeast Asian Village Dog Y Chromosomes Illuminates Dog Origins |
title_full |
Phylogenetic Distinctiveness of Middle Eastern and Southeast Asian Village Dog Y Chromosomes Illuminates Dog Origins |
title_fullStr |
Phylogenetic Distinctiveness of Middle Eastern and Southeast Asian Village Dog Y Chromosomes Illuminates Dog Origins |
title_full_unstemmed |
Phylogenetic Distinctiveness of Middle Eastern and Southeast Asian Village Dog Y Chromosomes Illuminates Dog Origins |
title_sort |
phylogenetic distinctiveness of middle eastern and southeast asian village dog y chromosomes illuminates dog origins |
publisher |
Public Library of Science |
publishDate |
2011 |
url |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3237445 http://www.ncbi.nlm.nih.gov/pubmed/22194840 https://doi.org/10.1371/journal.pone.0028496 |
long_lat |
ENVELOPE(-112.453,-112.453,57.591,57.591) |
geographic |
The ''Y'' |
geographic_facet |
The ''Y'' |
genre |
Canis lupus |
genre_facet |
Canis lupus |
op_relation |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3237445 http://www.ncbi.nlm.nih.gov/pubmed/22194840 http://dx.doi.org/10.1371/journal.pone.0028496 |
op_rights |
Brown et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
op_rightsnorm |
CC-BY |
op_doi |
https://doi.org/10.1371/journal.pone.0028496 |
container_title |
PLoS ONE |
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6 |
container_issue |
12 |
container_start_page |
e28496 |
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1766386107778334720 |