European genome-wide association study identifies SLC14A1 as a new urinary bladder cancer susceptibility gene

• Published in: Human Molecular Genetics
• Main Authors: Rafnar, Thorunn, Vermeulen, Sita H., Sulem, Patrick, Thorleifsson, Gudmar, Aben, Katja K., Witjes, J. Alfred, Grotenhuis, Anne J., Verhaegh, Gerald W., Hulsbergen-van de Kaa, Christina A., Besenbacher, Soren, Gudbjartsson, Daniel, Stacey, Simon N., Gudmundsson, Julius, Johannsdottir, Hrefna, Bjarnason, Hjordis, Zanon, Carlo, Helgadottir, Hafdis, Jonasson, Jon Gunnlaugur, Tryggvadottir, Laufey, Jonsson, Eirikur, Geirsson, Gudmundur, Nikulasson, Sigfus, Petursdottir, Vigdis, Bishop, D. Timothy, Chung-Sak, Sei, Choudhury, Ananya, Elliott, Faye, Barrett, Jennifer H., Knowles, Margaret A., de Verdier, Petra J., Ryk, Charlotta, Lindblom, Annika, Rudnai, Peter, Gurzau, Eugene, Koppova, Kvetoslava, Vineis, Paolo, Polidoro, Silvia, Guarrera, Simonetta, Sacerdote, Carlotta, Panadero, Angeles, Sanz-Velez, José I., Sanchez, Manuel, Valdivia, Gabriel, Garcia-Prats, Maria D., Hengstler, Jan G., Selinski, Silvia, Gerullis, Holger, Ovsiannikov, Daniel, Khezri, Abdolaziz, Aminsharifi, Alireza
• Format: Text
• Language: English
• Published: Oxford University Press 2011
• Subjects: Association Studies Articles; Kidd; Iceland
• Online Access: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3188988; http://www.ncbi.nlm.nih.gov/pubmed/21750109; https://doi.org/10.1093/hmg/ddr303

Three genome-wide association studies in Europe and the USA have reported eight urinary bladder cancer (UBC) susceptibility loci. Using extended case and control series and 1000 Genomes imputations of 5 340 737 single-nucleotide polymorphisms (SNPs), we searched for additional loci in the European G...