Why is Southern African canine babesiosis so virulent? An evolutionary perspective
Canine babesiosis is a common, highly virulent disease in Southern Africa with even pups and juveniles being severely affected. This contrasts with bovine babesiosis, for example, where host, parasite and vector co-evolved and young animals develop immunity after infection without showing clinical s...
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ftpubmed:oai:pubmedcentral.nih.gov:3094394 2023-05-15T15:50:24+02:00 Why is Southern African canine babesiosis so virulent? An evolutionary perspective Penzhorn, Barend L 2011-04-13 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3094394 http://www.ncbi.nlm.nih.gov/pubmed/21489239 https://doi.org/10.1186/1756-3305-4-51 en eng BioMed Central http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3094394 http://www.ncbi.nlm.nih.gov/pubmed/21489239 http://dx.doi.org/10.1186/1756-3305-4-51 Copyright ©2011 Penzhorn; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. CC-BY Review Text 2011 ftpubmed https://doi.org/10.1186/1756-3305-4-51 2013-09-03T14:39:14Z Canine babesiosis is a common, highly virulent disease in Southern Africa with even pups and juveniles being severely affected. This contrasts with bovine babesiosis, for example, where host, parasite and vector co-evolved and young animals develop immunity after infection without showing clinical signs. Babesia rossi, the main causative organism of canine babesiosis in sub-Saharan Africa, was first described from a side-striped jackal (Canis adustus) in Kenya. Although data are meagre, there is evidence that indigenous African canids, such as jackals and wild dogs (Lycaon pictus), can harbour the parasite without showing untoward effects. Dogs are not indigenous to Africa. The vast majority of dogs presented at veterinary facilities in South Africa represent recently introduced European, Asian or American breeds. The contention is that B. rossi is a new challenge to which these dogs have not adapted. With intensive treatment of clinical cases, natural selection is effectively negated and the status quo will probably be maintained indefinitely. It is postulated that Babesia vogeli, which frequently results in unapparent infections or mild manifestations in dogs, represents or is closely related to the ancestral form of the canine parasite, possibly originating from wolves (Canis lupus). Text Canis lupus PubMed Central (PMC) Parasites & Vectors 4 1 |
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Review Penzhorn, Barend L Why is Southern African canine babesiosis so virulent? An evolutionary perspective |
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Canine babesiosis is a common, highly virulent disease in Southern Africa with even pups and juveniles being severely affected. This contrasts with bovine babesiosis, for example, where host, parasite and vector co-evolved and young animals develop immunity after infection without showing clinical signs. Babesia rossi, the main causative organism of canine babesiosis in sub-Saharan Africa, was first described from a side-striped jackal (Canis adustus) in Kenya. Although data are meagre, there is evidence that indigenous African canids, such as jackals and wild dogs (Lycaon pictus), can harbour the parasite without showing untoward effects. Dogs are not indigenous to Africa. The vast majority of dogs presented at veterinary facilities in South Africa represent recently introduced European, Asian or American breeds. The contention is that B. rossi is a new challenge to which these dogs have not adapted. With intensive treatment of clinical cases, natural selection is effectively negated and the status quo will probably be maintained indefinitely. It is postulated that Babesia vogeli, which frequently results in unapparent infections or mild manifestations in dogs, represents or is closely related to the ancestral form of the canine parasite, possibly originating from wolves (Canis lupus). |
format |
Text |
author |
Penzhorn, Barend L |
author_facet |
Penzhorn, Barend L |
author_sort |
Penzhorn, Barend L |
title |
Why is Southern African canine babesiosis so virulent? An evolutionary perspective |
title_short |
Why is Southern African canine babesiosis so virulent? An evolutionary perspective |
title_full |
Why is Southern African canine babesiosis so virulent? An evolutionary perspective |
title_fullStr |
Why is Southern African canine babesiosis so virulent? An evolutionary perspective |
title_full_unstemmed |
Why is Southern African canine babesiosis so virulent? An evolutionary perspective |
title_sort |
why is southern african canine babesiosis so virulent? an evolutionary perspective |
publisher |
BioMed Central |
publishDate |
2011 |
url |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3094394 http://www.ncbi.nlm.nih.gov/pubmed/21489239 https://doi.org/10.1186/1756-3305-4-51 |
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Canis lupus |
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Canis lupus |
op_relation |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3094394 http://www.ncbi.nlm.nih.gov/pubmed/21489239 http://dx.doi.org/10.1186/1756-3305-4-51 |
op_rights |
Copyright ©2011 Penzhorn; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
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CC-BY |
op_doi |
https://doi.org/10.1186/1756-3305-4-51 |
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Parasites & Vectors |
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