Novel Hantavirus in the Flat-Skulled Shrew (Sorex roboratus)

Genetically distinct hantaviruses have been identified recently in multiple species of shrews (Order Soricomorpha, Family Soricidae) in Eurasia and North America. To corroborate decades-old reports of hantaviral antigens in shrews from Russia, archival liver and lung tissues from 4 Siberian large-to...

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Bibliographic Details
Published in:Vector-Borne and Zoonotic Diseases
Main Authors: Kang, Hae Ji, Arai, Satoru, Hope, Andrew G., Cook, Joseph A., Yanagihara, Richard
Format: Text
Language:English
Published: Mary Ann Liebert, Inc. 2010
Subjects:
Original Articles
Sakha
Sakha Republic
Tundra
Siberia
Online Access:http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2979330
http://www.ncbi.nlm.nih.gov/pubmed/20426682
https://doi.org/10.1089/vbz.2009.0159
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Summary:Genetically distinct hantaviruses have been identified recently in multiple species of shrews (Order Soricomorpha, Family Soricidae) in Eurasia and North America. To corroborate decades-old reports of hantaviral antigens in shrews from Russia, archival liver and lung tissues from 4 Siberian large-toothed shrews (Sorex daphaenodon), 5 Eurasian least shrews (Sorex minutissimus), 12 flat-skulled shrews (Sorex roboratus), and 18 tundra shrews (Sorex tundrensis), captured in the Sakha Republic in northeastern Siberia during July and August 2006, were analyzed for hantavirus RNA by reverse transcription–polymerase chain reaction. A novel hantavirus, named Kenkeme virus, was detected in a flat-skulled shrew. Sequence analysis of the full-length S and partial M and L segments indicated that Kenkeme virus was genetically and phylogenetically distinct from Seewis virus harbored by the Eurasian common shrew (Sorex araneus), as well as all other rodent-, soricid-, and talpid-borne hantaviruses.

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