Pathogenicity of Highly Pathogenic Avian Influenza Virus (H5N1) in Adult Mute Swans

Adult, healthy mute swans were experimentally infected with highly pathogenic avian influenza virus A/Cygnus cygnus/Germany/R65/2006 subtype H5N1. Immunologically naive birds died, whereas animals with preexisting, naturally acquired avian influenza virus–specific antibodies became infected asymptom...

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Bibliographic Details
Published in:Emerging Infectious Diseases
Main Authors: Kalthoff, Donata, Breithaupt, Angele, Teifke, Jens P., Globig, Anja, Harder, Timm, Mettenleiter, Thomas C., Beer, Martin
Format: Text
Language:English
Published: Centers for Disease Control and Prevention 2008
Subjects:
Dispatch
Cygnus cygnus
Online Access:http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2600380
http://www.ncbi.nlm.nih.gov/pubmed/18680652
https://doi.org/10.3201/eid1408.080078
Description
Summary:Adult, healthy mute swans were experimentally infected with highly pathogenic avian influenza virus A/Cygnus cygnus/Germany/R65/2006 subtype H5N1. Immunologically naive birds died, whereas animals with preexisting, naturally acquired avian influenza virus–specific antibodies became infected asymptomatically and shed virus. Adult mute swans are highly susceptible, excrete virus, and can be clinically protected by preexposure immunity.

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