Serum Concentrations of Polyfluoroalkyl Compounds in Faroese Whale Meat Consumers
To learn the extent of human exposure to polyfluoroalkyl compounds (PFCs) in a remote fishing population, we measured, in Faroese children and pregnant women, the serum concentrations of nine PFCs, including perfluorooctane sulfonate (PFOS), perfluorooctanoate (PFOA), and perfluorononanoate (PFNA),...
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ftpubmed:oai:pubmedcentral.nih.gov:2543091 2023-05-15T16:10:51+02:00 Serum Concentrations of Polyfluoroalkyl Compounds in Faroese Whale Meat Consumers Weihe, Pal Kato, Kayoko Calafat, Antonia M. Nielsen, Flemming Wanigatunga, Amal A. Needham, Larry L. Grandjean, Philippe 2008-08-15 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2543091 http://www.ncbi.nlm.nih.gov/pubmed/18767701 en eng http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2543091 http://www.ncbi.nlm.nih.gov/pubmed/18767701 Article Text 2008 ftpubmed 2013-09-02T05:43:54Z To learn the extent of human exposure to polyfluoroalkyl compounds (PFCs) in a remote fishing population, we measured, in Faroese children and pregnant women, the serum concentrations of nine PFCs, including perfluorooctane sulfonate (PFOS), perfluorooctanoate (PFOA), and perfluorononanoate (PFNA), by using on-line solid-phase extraction coupled to isotope dilution high-performance liquid chromatography-tandem mass spectrometry. The serum samples analyzed had been collected between 1993 and 2005 from 103 children 7 years of age, 79 of these children at 14 years of age, and from 12 pregnant women and their children 5 years later. PFOS was detected in all samples analyzed, and both PFOA and PFNA in all but one of the samples. The concentrations found are comparable to those reported elsewhere. Correlations between paired concentrations were poor. However, PFOS and PFNA concentrations correlated well with the frequency of pilot whale dinners and with concentrations of mercury and polychlorinated biphenyls. One whale meal every two weeks increased the PFOS concentration in 14-year olds by about 25% and PFNA by 50%. The high frequency of detection of most PFCs suggests widespread exposure in the Faroe Islands already by the early 1990s, with whale meat being an important source. Text Faroe Islands PubMed Central (PMC) Faroe Islands |
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Article Weihe, Pal Kato, Kayoko Calafat, Antonia M. Nielsen, Flemming Wanigatunga, Amal A. Needham, Larry L. Grandjean, Philippe Serum Concentrations of Polyfluoroalkyl Compounds in Faroese Whale Meat Consumers |
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To learn the extent of human exposure to polyfluoroalkyl compounds (PFCs) in a remote fishing population, we measured, in Faroese children and pregnant women, the serum concentrations of nine PFCs, including perfluorooctane sulfonate (PFOS), perfluorooctanoate (PFOA), and perfluorononanoate (PFNA), by using on-line solid-phase extraction coupled to isotope dilution high-performance liquid chromatography-tandem mass spectrometry. The serum samples analyzed had been collected between 1993 and 2005 from 103 children 7 years of age, 79 of these children at 14 years of age, and from 12 pregnant women and their children 5 years later. PFOS was detected in all samples analyzed, and both PFOA and PFNA in all but one of the samples. The concentrations found are comparable to those reported elsewhere. Correlations between paired concentrations were poor. However, PFOS and PFNA concentrations correlated well with the frequency of pilot whale dinners and with concentrations of mercury and polychlorinated biphenyls. One whale meal every two weeks increased the PFOS concentration in 14-year olds by about 25% and PFNA by 50%. The high frequency of detection of most PFCs suggests widespread exposure in the Faroe Islands already by the early 1990s, with whale meat being an important source. |
format |
Text |
author |
Weihe, Pal Kato, Kayoko Calafat, Antonia M. Nielsen, Flemming Wanigatunga, Amal A. Needham, Larry L. Grandjean, Philippe |
author_facet |
Weihe, Pal Kato, Kayoko Calafat, Antonia M. Nielsen, Flemming Wanigatunga, Amal A. Needham, Larry L. Grandjean, Philippe |
author_sort |
Weihe, Pal |
title |
Serum Concentrations of Polyfluoroalkyl Compounds in Faroese Whale Meat Consumers |
title_short |
Serum Concentrations of Polyfluoroalkyl Compounds in Faroese Whale Meat Consumers |
title_full |
Serum Concentrations of Polyfluoroalkyl Compounds in Faroese Whale Meat Consumers |
title_fullStr |
Serum Concentrations of Polyfluoroalkyl Compounds in Faroese Whale Meat Consumers |
title_full_unstemmed |
Serum Concentrations of Polyfluoroalkyl Compounds in Faroese Whale Meat Consumers |
title_sort |
serum concentrations of polyfluoroalkyl compounds in faroese whale meat consumers |
publishDate |
2008 |
url |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2543091 http://www.ncbi.nlm.nih.gov/pubmed/18767701 |
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Faroe Islands |
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Faroe Islands |
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Faroe Islands |
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Faroe Islands |
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2543091 http://www.ncbi.nlm.nih.gov/pubmed/18767701 |
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