Canine Distemper Virus Strains Circulating among North American Dogs▿
Canine distemper virus (CDV) is a highly contagious virus that causes multisystemic disease in dogs. We received seven samples from dogs with CD from the United States during 2007. CDV isolates from these samples formed large, multinucleated syncytia in a Vero cell line expressing canine signaling l...
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ftpubmed:oai:pubmedcentral.nih.gov:2292659 2023-05-15T15:02:38+02:00 Canine Distemper Virus Strains Circulating among North American Dogs▿ Kapil, Sanjay Allison, Robin W. Johnston, Larry Murray, Brandy L. Holland, Steven Meinkoth, Jim Johnson, Bill 2008-04 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2292659 http://www.ncbi.nlm.nih.gov/pubmed/18256210 https://doi.org/10.1128/CVI.00005-08 en eng American Society for Microbiology (ASM) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2292659 http://www.ncbi.nlm.nih.gov/pubmed/18256210 http://dx.doi.org/10.1128/CVI.00005-08 Copyright © 2008, American Society for Microbiology Veterinary Immunology Text 2008 ftpubmed https://doi.org/10.1128/CVI.00005-08 2013-09-01T17:47:52Z Canine distemper virus (CDV) is a highly contagious virus that causes multisystemic disease in dogs. We received seven samples from dogs with CD from the United States during 2007. CDV isolates from these samples formed large, multinucleated syncytia in a Vero cell line expressing canine signaling lymphocyte activation molecule (SLAM). Based on the hemagglutinin gene sequences, the CDV isolates from three states (California, Missouri, and Oklahoma) formed two CDV genetic groups: group I (major; six of seven isolates) consisted of CDV isolates closely related to the European wildlife lineage of CDV, and group II (minor; one of seven isolates) was genetically related to the Arctic-like lineage of CDV. However, both CDV groups were genetically different from the current vaccine strains that belong to the American-1 lineage of the old (1930 to 1950) CDV isolates. Text Arctic PubMed Central (PMC) Arctic Clinical and Vaccine Immunology 15 4 707 712 |
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English |
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Veterinary Immunology |
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Veterinary Immunology Kapil, Sanjay Allison, Robin W. Johnston, Larry Murray, Brandy L. Holland, Steven Meinkoth, Jim Johnson, Bill Canine Distemper Virus Strains Circulating among North American Dogs▿ |
topic_facet |
Veterinary Immunology |
description |
Canine distemper virus (CDV) is a highly contagious virus that causes multisystemic disease in dogs. We received seven samples from dogs with CD from the United States during 2007. CDV isolates from these samples formed large, multinucleated syncytia in a Vero cell line expressing canine signaling lymphocyte activation molecule (SLAM). Based on the hemagglutinin gene sequences, the CDV isolates from three states (California, Missouri, and Oklahoma) formed two CDV genetic groups: group I (major; six of seven isolates) consisted of CDV isolates closely related to the European wildlife lineage of CDV, and group II (minor; one of seven isolates) was genetically related to the Arctic-like lineage of CDV. However, both CDV groups were genetically different from the current vaccine strains that belong to the American-1 lineage of the old (1930 to 1950) CDV isolates. |
format |
Text |
author |
Kapil, Sanjay Allison, Robin W. Johnston, Larry Murray, Brandy L. Holland, Steven Meinkoth, Jim Johnson, Bill |
author_facet |
Kapil, Sanjay Allison, Robin W. Johnston, Larry Murray, Brandy L. Holland, Steven Meinkoth, Jim Johnson, Bill |
author_sort |
Kapil, Sanjay |
title |
Canine Distemper Virus Strains Circulating among North American Dogs▿ |
title_short |
Canine Distemper Virus Strains Circulating among North American Dogs▿ |
title_full |
Canine Distemper Virus Strains Circulating among North American Dogs▿ |
title_fullStr |
Canine Distemper Virus Strains Circulating among North American Dogs▿ |
title_full_unstemmed |
Canine Distemper Virus Strains Circulating among North American Dogs▿ |
title_sort |
canine distemper virus strains circulating among north american dogs▿ |
publisher |
American Society for Microbiology (ASM) |
publishDate |
2008 |
url |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2292659 http://www.ncbi.nlm.nih.gov/pubmed/18256210 https://doi.org/10.1128/CVI.00005-08 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_relation |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2292659 http://www.ncbi.nlm.nih.gov/pubmed/18256210 http://dx.doi.org/10.1128/CVI.00005-08 |
op_rights |
Copyright © 2008, American Society for Microbiology |
op_doi |
https://doi.org/10.1128/CVI.00005-08 |
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Clinical and Vaccine Immunology |
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15 |
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4 |
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707 |
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712 |
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1766334559295635456 |