Alloalbuminemia in North India.
Electrophoretic screening of sera from 550 individuals from Punjab, North India, revealed four cases of alloalbuminemia. Two albumin variants migrated slower and two migrated faster than the common albumin A. These variants were further analyzed by electrophoresis of their cyanogen bromide fragments...
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ftpubmed:oai:pubmedcentral.nih.gov:1685712 2023-05-15T17:14:15+02:00 Alloalbuminemia in North India. Kaur, H Franklin, S G Shrivastava, P K Blumberg, B S 1982-11 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1685712 http://www.ncbi.nlm.nih.gov/pubmed/7180851 en eng http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1685712 http://www.ncbi.nlm.nih.gov/pubmed/7180851 Research Article Text 1982 ftpubmed 2013-08-31T12:18:51Z Electrophoretic screening of sera from 550 individuals from Punjab, North India, revealed four cases of alloalbuminemia. Two albumin variants migrated slower and two migrated faster than the common albumin A. These variants were further analyzed by electrophoresis of their cyanogen bromide fragments to localize their molecular differences. One of the slow variants appears similar to, if not identical with, albumin B, with an altered cyanogen bromide fragment CNBr VII. The other slow variant appears to be a new variant (proposed name albumin Punjab) differing from albumin A in an altered fragment CNBr VI (which also occurs in albumins Kashmir and Adana) and in an altered fragment CNBr I. Among the fast variants, one has the same altered fragment CNBr V as albumin Naskapi, while the other appears to be a new variant (proposed name albumin Patiala) having an altered fragment CNBr VI. The presence of albumin Naskapi in Punjabis, North American Indians, and Eti Turks (previously reported) is consistent with the existence of a common ancestral population in which the mutation to Naskapi occurred before the migrations eastward and westward. Text naskapi PubMed Central (PMC) |
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Research Article Kaur, H Franklin, S G Shrivastava, P K Blumberg, B S Alloalbuminemia in North India. |
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Research Article |
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Electrophoretic screening of sera from 550 individuals from Punjab, North India, revealed four cases of alloalbuminemia. Two albumin variants migrated slower and two migrated faster than the common albumin A. These variants were further analyzed by electrophoresis of their cyanogen bromide fragments to localize their molecular differences. One of the slow variants appears similar to, if not identical with, albumin B, with an altered cyanogen bromide fragment CNBr VII. The other slow variant appears to be a new variant (proposed name albumin Punjab) differing from albumin A in an altered fragment CNBr VI (which also occurs in albumins Kashmir and Adana) and in an altered fragment CNBr I. Among the fast variants, one has the same altered fragment CNBr V as albumin Naskapi, while the other appears to be a new variant (proposed name albumin Patiala) having an altered fragment CNBr VI. The presence of albumin Naskapi in Punjabis, North American Indians, and Eti Turks (previously reported) is consistent with the existence of a common ancestral population in which the mutation to Naskapi occurred before the migrations eastward and westward. |
format |
Text |
author |
Kaur, H Franklin, S G Shrivastava, P K Blumberg, B S |
author_facet |
Kaur, H Franklin, S G Shrivastava, P K Blumberg, B S |
author_sort |
Kaur, H |
title |
Alloalbuminemia in North India. |
title_short |
Alloalbuminemia in North India. |
title_full |
Alloalbuminemia in North India. |
title_fullStr |
Alloalbuminemia in North India. |
title_full_unstemmed |
Alloalbuminemia in North India. |
title_sort |
alloalbuminemia in north india. |
publishDate |
1982 |
url |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1685712 http://www.ncbi.nlm.nih.gov/pubmed/7180851 |
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naskapi |
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naskapi |
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1685712 http://www.ncbi.nlm.nih.gov/pubmed/7180851 |
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1766071537568317440 |