Genetic studies of low abundance human plasma proteins. II. Population genetics of coagulation factor XIIIB.
Plasma samples from a large number of different ethnic groups, consisting of U.S. whites, U.S. blacks, Eskimos from Kodiak and St. Lawrence Island, Aleuts of the Pribilof Islands, and three Amerindian groups from Canada and Mexico have been analyzed by isoelectric focusing followed by immunoblotting...
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ftpubmed:oai:pubmedcentral.nih.gov:1684128 2023-05-15T16:07:13+02:00 Genetic studies of low abundance human plasma proteins. II. Population genetics of coagulation factor XIIIB. Kamboh, M I Ferrell, R E 1986-12 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1684128 http://www.ncbi.nlm.nih.gov/pubmed/3467588 en eng http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1684128 http://www.ncbi.nlm.nih.gov/pubmed/3467588 Research Article Text 1986 ftpubmed 2013-08-31T12:14:38Z Plasma samples from a large number of different ethnic groups, consisting of U.S. whites, U.S. blacks, Eskimos from Kodiak and St. Lawrence Island, Aleuts of the Pribilof Islands, and three Amerindian groups from Canada and Mexico have been analyzed by isoelectric focusing followed by immunoblotting to determine the magnitude of genetic variation at the F XIIIB structural locus. The synthesis of published data and our new data demonstrate remarkable variation in the distribution of the three common alleles at this locus and establishes F XIIIB as an extremely informative marker for population differentiation and evolutionary studies. Genetic distance analysis based on this variation separates Caucasian, black, and Mongoloid populations into three distinct clusters. Text eskimo* St Lawrence Island PubMed Central (PMC) Canada Lawrence Island ENVELOPE(-103.718,-103.718,56.967,56.967) |
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English |
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Research Article |
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Research Article Kamboh, M I Ferrell, R E Genetic studies of low abundance human plasma proteins. II. Population genetics of coagulation factor XIIIB. |
topic_facet |
Research Article |
description |
Plasma samples from a large number of different ethnic groups, consisting of U.S. whites, U.S. blacks, Eskimos from Kodiak and St. Lawrence Island, Aleuts of the Pribilof Islands, and three Amerindian groups from Canada and Mexico have been analyzed by isoelectric focusing followed by immunoblotting to determine the magnitude of genetic variation at the F XIIIB structural locus. The synthesis of published data and our new data demonstrate remarkable variation in the distribution of the three common alleles at this locus and establishes F XIIIB as an extremely informative marker for population differentiation and evolutionary studies. Genetic distance analysis based on this variation separates Caucasian, black, and Mongoloid populations into three distinct clusters. |
format |
Text |
author |
Kamboh, M I Ferrell, R E |
author_facet |
Kamboh, M I Ferrell, R E |
author_sort |
Kamboh, M I |
title |
Genetic studies of low abundance human plasma proteins. II. Population genetics of coagulation factor XIIIB. |
title_short |
Genetic studies of low abundance human plasma proteins. II. Population genetics of coagulation factor XIIIB. |
title_full |
Genetic studies of low abundance human plasma proteins. II. Population genetics of coagulation factor XIIIB. |
title_fullStr |
Genetic studies of low abundance human plasma proteins. II. Population genetics of coagulation factor XIIIB. |
title_full_unstemmed |
Genetic studies of low abundance human plasma proteins. II. Population genetics of coagulation factor XIIIB. |
title_sort |
genetic studies of low abundance human plasma proteins. ii. population genetics of coagulation factor xiiib. |
publishDate |
1986 |
url |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1684128 http://www.ncbi.nlm.nih.gov/pubmed/3467588 |
long_lat |
ENVELOPE(-103.718,-103.718,56.967,56.967) |
geographic |
Canada Lawrence Island |
geographic_facet |
Canada Lawrence Island |
genre |
eskimo* St Lawrence Island |
genre_facet |
eskimo* St Lawrence Island |
op_relation |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1684128 http://www.ncbi.nlm.nih.gov/pubmed/3467588 |
_version_ |
1766403280011788288 |