Pathogenic Potential of Novel Chlamydiae and Diagnostic Approaches to Infections Due to These Obligate Intracellular Bacteria

Novel chlamydiae are newly recognized members of the phylum Chlamydiales that are only distantly related to the classic Chlamydiaceae, i.e., Chlamydia and Chlamydophila species. They also exibit an obligate biphasic intracellular life cycle within eukaryote host cells. Some of these new chlamydiae a...

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Published in:Clinical Microbiology Reviews
Main Authors: Corsaro, Daniele, Greub, Gilbert
Format: Text
Language:English
Published: American Society for Microbiology 2006
Subjects:
Online Access:http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1471994
http://www.ncbi.nlm.nih.gov/pubmed/16614250
https://doi.org/10.1128/CMR.19.2.283-297.2006
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spelling ftpubmed:oai:pubmedcentral.nih.gov:1471994 2023-05-15T15:32:19+02:00 Pathogenic Potential of Novel Chlamydiae and Diagnostic Approaches to Infections Due to These Obligate Intracellular Bacteria Corsaro, Daniele Greub, Gilbert 2006-04 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1471994 http://www.ncbi.nlm.nih.gov/pubmed/16614250 https://doi.org/10.1128/CMR.19.2.283-297.2006 en eng American Society for Microbiology http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1471994 http://www.ncbi.nlm.nih.gov/pubmed/16614250 http://dx.doi.org/10.1128/CMR.19.2.283-297.2006 Copyright © 2006, American Society for Microbiology Reviews Text 2006 ftpubmed https://doi.org/10.1128/CMR.19.2.283-297.2006 2013-08-31T01:59:36Z Novel chlamydiae are newly recognized members of the phylum Chlamydiales that are only distantly related to the classic Chlamydiaceae, i.e., Chlamydia and Chlamydophila species. They also exibit an obligate biphasic intracellular life cycle within eukaryote host cells. Some of these new chlamydiae are currently considered potential emerging human and/or animal pathogens. Parachlamydia acanthamoebae and Simkania negevensis are both emerging respiratory human pathogens, Waddlia chondrophila could be a novel abortigenic bovine agent, and Piscichlamydia salmonis has recently been identified as an agent of the gill epitheliocystis in the Atlantic salmon. Fritschea spp. and Rhabdochlamydia spp. seem to be confined to arthropods, but some evidence for human exposure exists. In this review, we first summarize the data supporting a pathogenic potential of the novel chlamydiae for humans and other vertebrates and the interactions that most of these chlamydiae have with free-living amoebae. We then review the diagnostic approaches to infections potentially due to the novel chlamydiae, especially focusing on the currently available PCR-based protocols, mammalian cell culture, the amoebal coculture system, and serology. Text Atlantic salmon PubMed Central (PMC) Clinical Microbiology Reviews 19 2 283 297
institution Open Polar
collection PubMed Central (PMC)
op_collection_id ftpubmed
language English
topic Reviews
spellingShingle Reviews
Corsaro, Daniele
Greub, Gilbert
Pathogenic Potential of Novel Chlamydiae and Diagnostic Approaches to Infections Due to These Obligate Intracellular Bacteria
topic_facet Reviews
description Novel chlamydiae are newly recognized members of the phylum Chlamydiales that are only distantly related to the classic Chlamydiaceae, i.e., Chlamydia and Chlamydophila species. They also exibit an obligate biphasic intracellular life cycle within eukaryote host cells. Some of these new chlamydiae are currently considered potential emerging human and/or animal pathogens. Parachlamydia acanthamoebae and Simkania negevensis are both emerging respiratory human pathogens, Waddlia chondrophila could be a novel abortigenic bovine agent, and Piscichlamydia salmonis has recently been identified as an agent of the gill epitheliocystis in the Atlantic salmon. Fritschea spp. and Rhabdochlamydia spp. seem to be confined to arthropods, but some evidence for human exposure exists. In this review, we first summarize the data supporting a pathogenic potential of the novel chlamydiae for humans and other vertebrates and the interactions that most of these chlamydiae have with free-living amoebae. We then review the diagnostic approaches to infections potentially due to the novel chlamydiae, especially focusing on the currently available PCR-based protocols, mammalian cell culture, the amoebal coculture system, and serology.
format Text
author Corsaro, Daniele
Greub, Gilbert
author_facet Corsaro, Daniele
Greub, Gilbert
author_sort Corsaro, Daniele
title Pathogenic Potential of Novel Chlamydiae and Diagnostic Approaches to Infections Due to These Obligate Intracellular Bacteria
title_short Pathogenic Potential of Novel Chlamydiae and Diagnostic Approaches to Infections Due to These Obligate Intracellular Bacteria
title_full Pathogenic Potential of Novel Chlamydiae and Diagnostic Approaches to Infections Due to These Obligate Intracellular Bacteria
title_fullStr Pathogenic Potential of Novel Chlamydiae and Diagnostic Approaches to Infections Due to These Obligate Intracellular Bacteria
title_full_unstemmed Pathogenic Potential of Novel Chlamydiae and Diagnostic Approaches to Infections Due to These Obligate Intracellular Bacteria
title_sort pathogenic potential of novel chlamydiae and diagnostic approaches to infections due to these obligate intracellular bacteria
publisher American Society for Microbiology
publishDate 2006
url http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1471994
http://www.ncbi.nlm.nih.gov/pubmed/16614250
https://doi.org/10.1128/CMR.19.2.283-297.2006
genre Atlantic salmon
genre_facet Atlantic salmon
op_relation http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1471994
http://www.ncbi.nlm.nih.gov/pubmed/16614250
http://dx.doi.org/10.1128/CMR.19.2.283-297.2006
op_rights Copyright © 2006, American Society for Microbiology
op_doi https://doi.org/10.1128/CMR.19.2.283-297.2006
container_title Clinical Microbiology Reviews
container_volume 19
container_issue 2
container_start_page 283
op_container_end_page 297
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