mtDNA diversity in Chukchi and Siberian Eskimos: implications for the genetic history of Ancient Beringia and the peopling of the New World.
The mtDNAs of 145 individuals representing the aboriginal populations of Chukotka-the Chukchi and Siberian Eskimos-were subjected to RFLP analysis and control-region sequencing. This analysis showed that the core of the genetic makeup of the Chukchi and Siberian Eskimos consisted of three (A, C, and...
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ftpubmed:oai:pubmedcentral.nih.gov:1377559 2023-05-15T15:54:28+02:00 mtDNA diversity in Chukchi and Siberian Eskimos: implications for the genetic history of Ancient Beringia and the peopling of the New World. Starikovskaya, Y B Sukernik, R I Schurr, T G Kogelnik, A M Wallace, D C 1998-11 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1377559 http://www.ncbi.nlm.nih.gov/pubmed/9792876 en eng http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1377559 http://www.ncbi.nlm.nih.gov/pubmed/9792876 Research Article Text 1998 ftpubmed 2013-08-30T21:33:01Z The mtDNAs of 145 individuals representing the aboriginal populations of Chukotka-the Chukchi and Siberian Eskimos-were subjected to RFLP analysis and control-region sequencing. This analysis showed that the core of the genetic makeup of the Chukchi and Siberian Eskimos consisted of three (A, C, and D) of the four primary mtDNA haplotype groups (haplogroups) (A-D) observed in Native Americans, with haplogroup A being the most prevalent in both Chukotkan populations. Two unique haplotypes belonging to haplogroup G (formerly called "other" mtDNAs) were also observed in a few Chukchi, and these have apparently been acquired through gene flow from adjacent Kamchatka, where haplogroup G is prevalent in the Koryak and Itel'men. In addition, a 16111C-->T transition appears to delineate an "American" enclave of haplogroup A mtDNAs in northeastern Siberia, whereas the 16192C-->T transition demarcates a "northern Pacific Rim" cluster within this haplogroup. Furthermore, the sequence-divergence estimates for haplogroups A, C, and D of Siberian and Native American populations indicate that the earliest inhabitants of Beringia possessed a limited number of founding mtDNA haplotypes and that the first humans expanded into the New World approximately 34,000 years before present (YBP). Subsequent migration 16,000-13,000 YBP apparently brought a restricted number of haplogroup B haplotypes to the Americas. For millennia, Beringia may have been the repository of the respective founding sequences that selectively penetrated into northern North America from western Alaska. Text Chukchi Chukotka eskimo* Kamchatka Koryak Alaska Beringia Siberia PubMed Central (PMC) Pacific |
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Research Article Starikovskaya, Y B Sukernik, R I Schurr, T G Kogelnik, A M Wallace, D C mtDNA diversity in Chukchi and Siberian Eskimos: implications for the genetic history of Ancient Beringia and the peopling of the New World. |
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Research Article |
description |
The mtDNAs of 145 individuals representing the aboriginal populations of Chukotka-the Chukchi and Siberian Eskimos-were subjected to RFLP analysis and control-region sequencing. This analysis showed that the core of the genetic makeup of the Chukchi and Siberian Eskimos consisted of three (A, C, and D) of the four primary mtDNA haplotype groups (haplogroups) (A-D) observed in Native Americans, with haplogroup A being the most prevalent in both Chukotkan populations. Two unique haplotypes belonging to haplogroup G (formerly called "other" mtDNAs) were also observed in a few Chukchi, and these have apparently been acquired through gene flow from adjacent Kamchatka, where haplogroup G is prevalent in the Koryak and Itel'men. In addition, a 16111C-->T transition appears to delineate an "American" enclave of haplogroup A mtDNAs in northeastern Siberia, whereas the 16192C-->T transition demarcates a "northern Pacific Rim" cluster within this haplogroup. Furthermore, the sequence-divergence estimates for haplogroups A, C, and D of Siberian and Native American populations indicate that the earliest inhabitants of Beringia possessed a limited number of founding mtDNA haplotypes and that the first humans expanded into the New World approximately 34,000 years before present (YBP). Subsequent migration 16,000-13,000 YBP apparently brought a restricted number of haplogroup B haplotypes to the Americas. For millennia, Beringia may have been the repository of the respective founding sequences that selectively penetrated into northern North America from western Alaska. |
format |
Text |
author |
Starikovskaya, Y B Sukernik, R I Schurr, T G Kogelnik, A M Wallace, D C |
author_facet |
Starikovskaya, Y B Sukernik, R I Schurr, T G Kogelnik, A M Wallace, D C |
author_sort |
Starikovskaya, Y B |
title |
mtDNA diversity in Chukchi and Siberian Eskimos: implications for the genetic history of Ancient Beringia and the peopling of the New World. |
title_short |
mtDNA diversity in Chukchi and Siberian Eskimos: implications for the genetic history of Ancient Beringia and the peopling of the New World. |
title_full |
mtDNA diversity in Chukchi and Siberian Eskimos: implications for the genetic history of Ancient Beringia and the peopling of the New World. |
title_fullStr |
mtDNA diversity in Chukchi and Siberian Eskimos: implications for the genetic history of Ancient Beringia and the peopling of the New World. |
title_full_unstemmed |
mtDNA diversity in Chukchi and Siberian Eskimos: implications for the genetic history of Ancient Beringia and the peopling of the New World. |
title_sort |
mtdna diversity in chukchi and siberian eskimos: implications for the genetic history of ancient beringia and the peopling of the new world. |
publishDate |
1998 |
url |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1377559 http://www.ncbi.nlm.nih.gov/pubmed/9792876 |
geographic |
Pacific |
geographic_facet |
Pacific |
genre |
Chukchi Chukotka eskimo* Kamchatka Koryak Alaska Beringia Siberia |
genre_facet |
Chukchi Chukotka eskimo* Kamchatka Koryak Alaska Beringia Siberia |
op_relation |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1377559 http://www.ncbi.nlm.nih.gov/pubmed/9792876 |
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