Immunochemistry of sperm-whale myoglobins prepared with various modified porphyrins and metalloporphyrins
1. The preparation and characterization of manganese, iron, cobalt, nickel, copper and zinc metalloporphyrins is described. Ferrihaem was also esterified with pyrid-4-ylpropanol and the derivative characterized as the diester. 2. Complexes of these various porphyrins, as well as protoporphyrin IX, w...
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ftpubmed:oai:pubmedcentral.nih.gov:1270364 2023-05-15T18:26:42+02:00 Immunochemistry of sperm-whale myoglobins prepared with various modified porphyrins and metalloporphyrins Atassi, M. Z. 1967-04 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1270364 http://www.ncbi.nlm.nih.gov/pubmed/6068005 en eng http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1270364 http://www.ncbi.nlm.nih.gov/pubmed/6068005 Articles Text 1967 ftpubmed 2013-08-30T16:30:56Z 1. The preparation and characterization of manganese, iron, cobalt, nickel, copper and zinc metalloporphyrins is described. Ferrihaem was also esterified with pyrid-4-ylpropanol and the derivative characterized as the diester. 2. Complexes of these various porphyrins, as well as protoporphyrin IX, with apomyoglobin were formed and the resulting artificial myoglobins characterized. 3. Very little complex-formation was obtained with nickel, cobalt and manganese metalloporphyrins and apomyoglobin. 4. Myoglobin prepared with copper metalloporphyrin was immunochemically identical with native ferrimyoglobin. All the other artificial myoglobins were less reactive to varying degrees. 5. The changes in antigenic reactivities were attributed to conformational reorganization caused by the different co-ordination tendencies of the various metals or by the modification of the side chains of the haem. Text Sperm whale PubMed Central (PMC) |
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Articles Atassi, M. Z. Immunochemistry of sperm-whale myoglobins prepared with various modified porphyrins and metalloporphyrins |
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Articles |
description |
1. The preparation and characterization of manganese, iron, cobalt, nickel, copper and zinc metalloporphyrins is described. Ferrihaem was also esterified with pyrid-4-ylpropanol and the derivative characterized as the diester. 2. Complexes of these various porphyrins, as well as protoporphyrin IX, with apomyoglobin were formed and the resulting artificial myoglobins characterized. 3. Very little complex-formation was obtained with nickel, cobalt and manganese metalloporphyrins and apomyoglobin. 4. Myoglobin prepared with copper metalloporphyrin was immunochemically identical with native ferrimyoglobin. All the other artificial myoglobins were less reactive to varying degrees. 5. The changes in antigenic reactivities were attributed to conformational reorganization caused by the different co-ordination tendencies of the various metals or by the modification of the side chains of the haem. |
format |
Text |
author |
Atassi, M. Z. |
author_facet |
Atassi, M. Z. |
author_sort |
Atassi, M. Z. |
title |
Immunochemistry of sperm-whale myoglobins prepared with various modified porphyrins and metalloporphyrins |
title_short |
Immunochemistry of sperm-whale myoglobins prepared with various modified porphyrins and metalloporphyrins |
title_full |
Immunochemistry of sperm-whale myoglobins prepared with various modified porphyrins and metalloporphyrins |
title_fullStr |
Immunochemistry of sperm-whale myoglobins prepared with various modified porphyrins and metalloporphyrins |
title_full_unstemmed |
Immunochemistry of sperm-whale myoglobins prepared with various modified porphyrins and metalloporphyrins |
title_sort |
immunochemistry of sperm-whale myoglobins prepared with various modified porphyrins and metalloporphyrins |
publishDate |
1967 |
url |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1270364 http://www.ncbi.nlm.nih.gov/pubmed/6068005 |
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Sperm whale |
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Sperm whale |
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1270364 http://www.ncbi.nlm.nih.gov/pubmed/6068005 |
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1766208678781779968 |